Activation of Wnt/β-catenin signaling decreases mRNA expressions of <i>Scx</i>, <i>Mkx</i> and <i>Tnmd</i> in rat TDCs. by Yasuzumi Kishimoto (4282138)

“…<p>Relative expressions of <i>Axin2</i>, <i>Scx</i>, <i>Mkx</i>, and <i>Tnmd</i> in TDCs treated with 50 ng/ml Wnt3a with or without 5 μM IWR (an inhibitor of β-catenin) <b>(A)</b>, 0 to 4 μM BIO (an activator of β-catenin) <b>(B)</b>, or 0 to 20 μM IWR <b>(C)</b> for 72 hrs. …”

MiR-24 is required for blood development from mouse embryonic stem cells. by Lynn Roy (687524)

“…Error bars represent the standard error of the mean (SEM).</p>…”

Glucose decreases the ability of HNF4α to activate the transcription of the <i>NR2F2</i> proximal promoter and to bind its chromatin target. by Marie Boutant (164748)

Discovery of Novel Acridane-Based Tubulin Polymerization Inhibitors with Anticancer and Potential Immunomodulatory Effects by Xiaopeng Peng (9136955)

“…The most potent compound <b>NT-6</b> exhibited high tubulin polymerization inhibitory activity (IC₅₀ = 1.5 μM) and remarkable antiproliferative potency against four cancer cell lines with an average IC₅₀ of 30 nM, better than colchicine and the hit compound <b>1f</b> (IC₅₀ of 65 and 126 nM, respectively). …”

Discovery of Novel Acridane-Based Tubulin Polymerization Inhibitors with Anticancer and Potential Immunomodulatory Effects by Xiaopeng Peng (9136955)

“…The most potent compound <b>NT-6</b> exhibited high tubulin polymerization inhibitory activity (IC₅₀ = 1.5 μM) and remarkable antiproliferative potency against four cancer cell lines with an average IC₅₀ of 30 nM, better than colchicine and the hit compound <b>1f</b> (IC₅₀ of 65 and 126 nM, respectively). …”

The effect of novel synthetic communities on plant shoot Pi content can be predicted by an NN. by Sur Herrera Paredes (674875)

“…The validation prediction error on NN is significantly smaller than LM (<i>p</i>-value = 5.25 × 10⁻¹⁰) and INT (<i>p</i>-value = 4.65 × 10⁻⁷). …”

Overexpression of SOCS1 decreases the antiviral effect of IFN-γ and tyrosine phosphorylation of STAT1 during MHV-68 infection in NIH3T3 fibroblasts. by Yong Shen (284972)

The synchronous activity of SGN fiber populations is disrupted and their response to sound is decreased with increasing levels of <i>L</i>_<i>u</i> heterogeneity. by Maral Budak (6680351)

Calcium release from <i>S</i>. <i>mutans</i> at decreasing pHs. by Tarcísio Jorge Leitão (4811379)

Comparison between mean-field solutions and simulations on networks. by Valeria d’Andrea (12095838)

Decreased proliferation in <i>Csf1r^−/−</i> and <i>Csf1^op/op</i> mouse colonic epithelium. by Duy Huynh (381445)

“…Bar = 50 µm. Means are depicted by horizontal bars, n = 3 per group, *<b>*</b>P<0.01, *P<0.05, using unpaired two-tailed t-test. …”

IQG-607 decreases the infection of macrophages by <i>L</i>. <i>braziliensis</i> amastigotes. by Camila F. Amorim (676792)

BrdU-positive mossy cell precursors are decreased in the hilus of developing Rac1^N/Rac3^KO mice. by Roberta Pennucci (83950)

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…The rates of hydrolysis at acidic pH* decreased when the primary amine N-donors (NN = en, <i>t</i>_1/2 = 0.6 h at 318 K) are replaced with π-accepting pyridine groups (e.g., NN = phen, <i>t</i>_1/2 = 9.5 h at 318 K). …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…The rates of hydrolysis at acidic pH* decreased when the primary amine N-donors (NN = en, <i>t</i>_1/2 = 0.6 h at 318 K) are replaced with π-accepting pyridine groups (e.g., NN = phen, <i>t</i>_1/2 = 9.5 h at 318 K). …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…The rates of hydrolysis at acidic pH* decreased when the primary amine N-donors (NN = en, <i>t</i>_1/2 = 0.6 h at 318 K) are replaced with π-accepting pyridine groups (e.g., NN = phen, <i>t</i>_1/2 = 9.5 h at 318 K). …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…The rates of hydrolysis at acidic pH* decreased when the primary amine N-donors (NN = en, <i>t</i>_1/2 = 0.6 h at 318 K) are replaced with π-accepting pyridine groups (e.g., NN = phen, <i>t</i>_1/2 = 9.5 h at 318 K). …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…The rates of hydrolysis at acidic pH* decreased when the primary amine N-donors (NN = en, <i>t</i>_1/2 = 0.6 h at 318 K) are replaced with π-accepting pyridine groups (e.g., NN = phen, <i>t</i>_1/2 = 9.5 h at 318 K). …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…The rates of hydrolysis at acidic pH* decreased when the primary amine N-donors (NN = en, <i>t</i>_1/2 = 0.6 h at 318 K) are replaced with π-accepting pyridine groups (e.g., NN = phen, <i>t</i>_1/2 = 9.5 h at 318 K). …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…The rates of hydrolysis at acidic pH* decreased when the primary amine N-donors (NN = en, <i>t</i>_1/2 = 0.6 h at 318 K) are replaced with π-accepting pyridine groups (e.g., NN = phen, <i>t</i>_1/2 = 9.5 h at 318 K). …”