DataSheet1_Interaction of Serum Alkaline Phosphatase and Folic Acid Treatment on Chronic Kidney Disease Progression in Treated Hypertensive Adults.docx by Yuanyuan Zhang (101797)

“…The primary outcome was CKD progression, defined as a decrease in estimated glomerular filtration rate (eGFR) of ≥30% and to a level of <60 ml/min/1.73 m² if baseline eGFR was ≥60 ml/min/1.73 m²; or a decrease in eGFR of ≥50% if baseline eGFR was <60 ml/min/1.73 m²; or end-stage renal disease. …”

Preclinical mouse model to monitor live Muc5b-producing conjunctival goblet cell density under pharmacological treatments by Céline Portal (3876436)

“…Ten days of BAK in one eye followed by 4 days without any treatment induced a −18.3% decrease in conjunctival goblet cell density. …”

Difference in GHG emissions (<em>x</em>-axis) and food availability (<em>y</em>-axis) in 2050 for the different scenarios with respect to 'TREND' by H Valin (557174)

“…</strong> Difference in GHG emissions (<em>x</em>-axis) and food availability (<em>y</em>-axis) in 2050 for the different scenarios with respect to 'TREND'. Panels (A)–(C) and (D) delineate domains where food provision increases ((A), (B)) or decreases ((C), (D)) and GHG emission savings increase ((B), (D)) or decrease ((A), (C)). …”

Data_Sheet_1_Effect of Lockdown Amid COVID-19 on Ambient Air Quality in 16 Indian Cities.docx by Amit Kumar Mishra (5644676)

“…SO₂ and O₃ showed an increase over a few cities as well as a decrease over the other cities. …”

Cardiac chambers undergo regionalised reduction in cell size. by Juliana Sánchez-Posada (20636677)

“…<p>(A–D) Quantification of internuclear cardiomyocyte distance as a proxy for cell size reveals an early increase in atrial cardiomyocyte size and a later reduction in ventricular cardiomyocyte size. …”

Neurochemical identity of dFB^23E10Ո^84C10 neurons. by Joseph D. Jones (13883524)

“…<b>(K)</b> Box plots of total sleep change in % ((total sleep on activation day-total sleep on baseline day/total sleep on baseline day) × 100) for control (<i>Empty-Split>CsChrimson</i>), <i>VGlut-AD; 84C10-DBD>CsChrimson</i> and <i>84C10-AD; ChAT-DBD>CsChrimson</i> female flies under a 50 Hz optogenetic activation protocol. Two-way ANOVA followed by Sidak’s multiple comparisons revealed that activating 84C10-AD; ChAT-DBD neurons significantly increases sleep. n.s. = not significant, ****<i>P</i> < 0.0001. …”

Renal phenotype of male Akita mice by genetic background. by Jae-Hyung Chang (327325)

“…<p>NR: not reported, ND: Not detected,</p>*<p>Compared to strain matched non-diabetic controls,</p>†<p>Animal models of diabetic complications consortium (ADMCC) criteria: >10-fold increase in albuminuria, >50% decrease in GFR over the lifetime of the animal, Advanced mesangial expansion, Arteriolar hylanosis, >50% increase in GBM thickness, Tubulointerstitial fibrosis,</p>**<p>variable (see text for discussion),</p>‡<p>Increased BUN at 30–40 weeks of age, References: <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Breyer1" target="_blank">[3]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Gurley1" target="_blank">[4]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Gurley2" target="_blank">[5]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Susztak1" target="_blank">[13]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Brosius1" target="_blank">[30]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Hong1" target="_blank">[35]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033942#pone.0033942-Haseyama1" target="_blank">[48]</a>.…”

Syntaxin1A Is Assembled in Toxin-Resistant Complexes That Are Disassembled by NSF/α-SNAP or by Sperm Activation by Gerardo A. De Blas (262394)

“…The toxin treatment in resting sperm (BoNT/C) or B-AM-loaded sperm (B-AM→BoNT/C) had no effect on the syntaxin labeling compared to untreated sperm (control). However, when 310 nM NSF and 500 nM α-SNAP were added to the system to promote the disassembly of SNARE complexes, the toxin significantly decreased the syntaxin labeling (B-AM→NSF/αS→BoNT/C). …”

Ex vivo fitness, CTL escape phenotype and sequence evolution of <i>gag</i> p24 CTL escape mutants. by Ryan M. Troyer (265934)

“…The fold escape conferred by each mutation is displayed here as the ratio of effective peptide concentration (EC₅₀) required to elicit 50% of maximal ELISpot signal relative to the pre-escape peptide <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000365#ppat.1000365-Cao2" target="_blank">[54]</a>. …”

Gemcitabine and ATR inhibitor synergism and effects on the cell cycle and DNA damage in U-CHCF365 and UM-Chor1 (Batch 1) by Chordoma Foundation (4391989)

“…The concentrations of gemcitabine and elimusertib used for U-CHCF365 were 5nM and 100nM, respectively, with those doses combined in the combination. …”

<i>apol1</i> morphant zebrafish embryos display generalized edema and glomerular filtration defects indicative of nephropathy. by Blair R. Anderson (765261)

“…<p>Representative live images of (A) sham-injected control larvae, and (B) <i>apol1</i> morpholino (MO) injected larvae at 5 dpf. <i>apol1</i> morphants display pericardial and yolk sac edema. …”

OSTEOTOMY AT THE BASE OF FEMORAL NECK AND OSTEOPLASTY FOR THE TREAMENT OF SCFE by LARISSA MARTINS GARCIA (14108288)

“…No differences were observed between the SCFE and control cohort for the functional scores (HHS, 94 ± 7 vs 100 ± 1, p = 0.135); except for ROM, with increased internal rotation (37.3º ± 9.4º vs 28.7º ± 8.2º, p < 0.001), and strength, with decreased abduction torque (75.5 ± 36.9 Nm/Kg vs 88.5 ± 27.6 Nm/Kg, p = 0.045) in the SCFE cohort. …”

Osmosensitivity of Transient Receptor Potential Vanilloid 1 Is Synergistically Enhanced by Distinct Activating Stimuli Such as Temperature and Protons by Eri Nishihara (213957)

Birds in Anthropogenic Landscapes: The Responses of Ecological Groups to Forest Loss in the Brazilian Atlantic Forest by José Carlos Morante-Filho (756360)

“…However, a decrease in forest cover had a negative effect on diversity of forest-specialist, frugivorous and insectivorous birds, and a positive effect on generalist birds. …”

Overexpression of miR-105 mimic inhibits anchorage-independent growth of prostate tumour cells. by D. Rice Honeywell (442714)

“…<p>(A–D) PC3 (A) and DU145 (B) cells were transfected with either 50 nM miR-105 or control mimic and 24 hours post-transfection were seeded in soft-agarose. …”

Odor-evoked activity in the MOE and VNO is required for female sexual receptivity. by Eleanor J. Fraser (529109)

“…(B) Males showed comparable frequency of anogenital chemoinvestigation (sniffing) to females of all genotypes. (C) A majority of females of all genotypes were mounted by WT males in ≥50% of assays. …”

Inference of Sparse Networks with Unobserved Variables. Application to Gene Regulatory Networks by Nikolai Slavov (576109)

“…<p>Networks are a unifying framework for modeling complex systems and network inference problems are frequently encountered in many fields. …”

RIG-I expression in neurons following JEV-infection. by Arshed Nazmi (215284)

“…Magnification ×20; scale bar corresponds to 50 µ (A). Immunoblotting from whole brain lysates and their densitometric analysis showed increased (approximately 5-fold) expression of RIG-I in JEV-infected and JEV+S-MO groups. 3′MO treatment caused a significant decrease in RIG-I levels. …”

Figure S1 - Contingent Kernel Density Estimation by Scott Fortmann-Roe (24544)

“…Iterations were then carried out using different values of <i>a</i>. Values of 0.10, 0.50, and 0.75 are shown. …”

Percentile plot showing the slope for BMI vs. years of education (Y-axis) at each percentile of the BMI distribution (X-axis). by Paul T. Williams (251599)

“…<p>For example, each addition year of education in Study 1 females was associated with a BMI decrease of (slope±SE) −0.117±0.018 kg/m² at the 10^th percentile of their BMI distribution (A), −0.117±0.016 kg/m² at their 25^th percentile (B), −0.165±0.020 kg/m² at their 50^th percentile (C, the median), −0.245±0.029 kg/m² at their 75^th percentile (D), and −0.300±0.046 kg/m² at their 90^th percentile (E, compare with <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0027657#pone-0027657-g001" target="_blank">Figure 1</a>). …”