5‑Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer’s Disease Phenotypes by Hsueh-Yun Lee (141907)

“…<i>N</i>-Hydroxy-4-((5-(4-methoxybenzoyl)-1<i>H</i>-indol-1-yl)­methyl)­benzamide (<b>6</b>) has potent inhibitory selectivity against histone deacetylase 6 (HDAC6) with an IC₅₀ value of 3.92 nM. …”

The effect of α-MSH treatment on the permeability of cytokine treated Caco-2 monolayers. by Judit Váradi (507449)

Secretion of IL-6 and IL-8 in Caco-2 cells treated with cytokines and α-MSH. by Judit Váradi (507449)

Immunohistochemical staining and analysis of NF-κB activation in cytokine- and α-MSH-treated Caco-2 cells. by Judit Váradi (507449)

The effect of α-MSH treatment on the immunostaining of tight juntion proteins claudin-4 and ZO-1 in cytokine treated Caco-2 cells. by Judit Váradi (507449)

The effect of different concentrations of α-MSH on the electrical resistance of cytokine treated Caco-2 monolayers. by Judit Váradi (507449)

Differential gene expression assay EC₅₀ values in Huh-7 cells and PHH. by Xuan G. Luong (9761423)

Treatment with mitochondrial shuttle inhibitors, GKA50, Ranolazine and glucose results in significant decreases in superoxide concentration as detected by coelenterazine chemilumin... by Laura L. Bronsart (844933)

<i>In vivo</i> epigenetic therapy sensitize CRC cell line xenografts to decrease tumor burden. by Anup Sharma (253963)

Correlation between hub genes and 50 hallmark signaling pathways. by Jiyong Zhang (2498740)

Regions (α-helices, β-sheets, and loops) showing an average increase or decrease of RMSF in the MTs compared to the WT; RMSF of a particular structure is taken to be increased or decreased if there is an average change in RMSF of >0.03 nm in at least ≥50% of its residues. by Kumaraswamy Naidu Chitrala (612025)

“…<p>Regions (α-helices, β-sheets, and loops) showing an average increase or decrease of RMSF in the MTs compared to the WT; RMSF of a particular structure is taken to be increased or decreased if there is an average change in RMSF of >0.03 nm in at least ≥50% of its residues.…”

Cell viability as measured by MTT absorbance (abs) at 570nm, LDH release and intracellular NAD levels of microglial cells after 48 hour incubation in pooled, non heat inactivated a... by Tharusha Jayasena (704509)

DMB treatment improved neurological deficit and decreased infarct volume 24 h after MCAO. by Huinan Zhang (849524)

The material parameters of the 50 MPa concrete for the simulations [26]. by Xiaochao Jin (3993236)

3D snapshots of the tumor system with single-agent BHQ880 treatment at (a) time step 40, (b) time step 50 and (c) time step 120. by Minna Qiao (836556)

Effect of the Hill coefficient on estimates of <i>ε</i>_max (left column) and IC₅₀ (right column) for the logistic model with drug applied to the growth rate <... by Hope Murphy (8843516)

Partial correlation of <i>ε</i>_max (left column) and IC₅₀ (right column) estimates at 10 days and 20 days (first and second bar of each color, respectively) o... by Hope Murphy (8843516)

E₅₀ values. by Junxia Zhou (14381598)

The effect of caspase-1 inhibitor on HIV-induced changes in IL-18 and IL-18BP in IEC. by Ossama Allam (5043434)

IL-18-induced cell death is partially inhibited by inhibitors of caspase-1 and caspase-3. by Ossama Allam (5043434)