Showing 281 - 300 results of 29,240 for search '(( 5 ((nm decrease) OR (nn decrease)) ) OR ( 50 ((teer decrease) OR (a decrease)) ))', query time: 0.82s Refine Results
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    Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease by Huashen Xu (13987046)

    Published 2025
    “…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC<sub>50</sub> = 0.1 nM, msEH IC<sub>50</sub> = 0.1 nM). …”
  12. 292

    Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease by Huashen Xu (13987046)

    Published 2025
    “…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC<sub>50</sub> = 0.1 nM, msEH IC<sub>50</sub> = 0.1 nM). …”
  13. 293

    Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease by Huashen Xu (13987046)

    Published 2025
    “…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC<sub>50</sub> = 0.1 nM, msEH IC<sub>50</sub> = 0.1 nM). …”
  14. 294

    Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease by Huashen Xu (13987046)

    Published 2025
    “…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC<sub>50</sub> = 0.1 nM, msEH IC<sub>50</sub> = 0.1 nM). …”
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    Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

    Published 2021
    “…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC<sub>50</sub> value of 6 nM). …”
  19. 299

    Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

    Published 2021
    “…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC<sub>50</sub> value of 6 nM). …”
  20. 300

    Effects of intracellular treatment with 5- or 40-nm AuNPs on AP properties in hippocampal CA1 neurons. by Seungmoon Jung (534987)

    Published 2014
    “…<p>(A) AuNPs of both sizes significantly decreased the latency to the first AP. The 40-nm AuNPs significantly reduced the AP threshold (B) and AP duration (C). …”