Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1<i>H</i>‑Indol-3-yl)‑1<i>H</i>‑imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting... by Qinghui Wang (2042065)

“…In vitro, biological studies showed that new ABI-231 analogues disrupt tubulin polymerization, promote microtubule fragmentation, and inhibit cancer cell migration. In vivo, analogue <b>10bb</b> not only significantly inhibits primary tumor growth and decreases tumor metastasis in melanoma xenograft models but also shows a significant ability to overcome paclitaxel resistance in a taxane-resistant PC-3/TxR model. …”

Antibodies used for flow cytometry experiments. by Joseph Rabin (7399436)

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Subject flow diagram. by Joseph Rabin (7399436)

Subjects:

Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy by Viviana A. Cavieres (500139)

“…To investigate the contribution of autophagy, we tested the effect of IDN5706 in Atg5-depleted cells. …”

Image_1_Decreased Serum Brain-Derived Neurotrophic Factor in Poststroke Depression: A Systematic Review and Meta-Analysis.pdf by Chunhui Zhang (337556)

Image_2_Decreased Serum Brain-Derived Neurotrophic Factor in Poststroke Depression: A Systematic Review and Meta-Analysis.pdf by Chunhui Zhang (337556)

Table_1_Decreased Serum Brain-Derived Neurotrophic Factor in Poststroke Depression: A Systematic Review and Meta-Analysis.DOCX by Chunhui Zhang (337556)

GXMGal effect on Treg cell intracellular cytokines production. by Eva Pericolini (290617)

GXMGal effect on Treg cell suppressive activity. by Eva Pericolini (290617)

GXMGal effect on Treg cell response. by Eva Pericolini (290617)

Image2_A Novel Plant Leaf Patch Absorbed With IL-33 Antibody Decreases Venous Neointimal hyperplasia.TIFF by Boao Xie (11621803)

“…IL-33 plays a role in the neointimal formation after vascular injury. We hypothesized that plant leaves can absorb therapeutic drug solution and can be used as a patch with drug delivery capability, and plant leaves absorbed with IL-33 antibody can decrease venous neointimal hyperplasia in the rat IVC venoplasty model.…”

Image1_A Novel Plant Leaf Patch Absorbed With IL-33 Antibody Decreases Venous Neointimal hyperplasia.TIFF by Boao Xie (11621803)

“…IL-33 plays a role in the neointimal formation after vascular injury. We hypothesized that plant leaves can absorb therapeutic drug solution and can be used as a patch with drug delivery capability, and plant leaves absorbed with IL-33 antibody can decrease venous neointimal hyperplasia in the rat IVC venoplasty model.…”

GXMGal effect on Th17 response. by Eva Pericolini (290617)

METTL10 tri-methylates K318 in EF1A1. by Tadahiro Shimazu (619411)

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Video1_Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex.avi by Wesam S. Ahmed (10170053)

Video3_Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex.avi by Wesam S. Ahmed (10170053)

Video4_Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex.avi by Wesam S. Ahmed (10170053)

Video2_Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex.avi by Wesam S. Ahmed (10170053)

Video2_Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex.avi by Wesam S. Ahmed (10170053)

Video6_Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex.MOV by Wesam S. Ahmed (10170053)