Functions of <i>GmNN1/FT2a</i> in nitrogen nutrition and nodulation. by Xinxin Li (281237)

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Fully Transparent and Rollable Electronics by Mallory Mativenga (1681909)

“…For handling purposes, carrier glass is used during fabrication, together with a very thin (∼1 nm) solution-processed carbon nanotube (CNT)/graphene oxide (GO) backbone that is first spin-coated on the glass to decrease adhesion of the CPI to the glass; peel strength of the CPI from glass decreases from 0.43 to 0.10 N/cm, which eases the process of detachment performed after device fabrication. …”

Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease by Christine M. LaPash Daniels (796881)

“…Here we tested whether lithium treatment would decrease levels of GFAP in a mouse model of Alexander disease. …”

<i>SIRT6</i> Minor Allele Genotype Is Associated with >5-Year Decrease in Lifespan in an Aged Cohort by Mindi J. TenNapel (679433)

DataSheet_1_Circulating exosomes decrease in size and increase in number between birth and age 7: relations to fetal growth and liver fat.pdf by Marta Díaz (337207)

“…Circulating exosomes of SGAs (as compared to those of AGAs) had a larger size at birth [146.8 vs 137.8 nm, respectively; p=0.02], and were in lower number at ages 2 [4.3x10¹¹vs 5.6x10¹¹ particles/mL, respectively; p=0.01] and 7 [6.3x10¹¹vs 6.8x10¹¹ particles/mL, respectively; p=0.006]. …”

Arginine supplementation decreases the inhibitory effect exerted by 5-flucytosine in <i>C</i>. <i>glabrata</i>. by Catarina Costa (322963)

Four-fold decrease in [H⁺]_e shifted GLT-1a E_rev by −18 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

“…Arrows show GLT-1a E_rev shifts. <b>(C)</b> Average GLT-1 E_rev shifts at 37.5 μM and 600 μM are approximately equal when [H⁺]_e was decreased from 40 to 10 nM.…”

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…By compiling a global data set of 1,782 paired observations from 185 publications, we show that land use conversion from natural to managed ecosystems significantly reduced NNM by 7.5% (−11.5, −2.8%) and increased NN by 150% (86, 194%), indicating decreasing N availability while increasing potential N loss through denitrification and nitrate leaching. …”

Incubation of <i>T</i>. <i>brucei</i> with Pol I transcription inhibitors results in a dramatic decrease in VEX1 foci. by Louise E. Kerry (3815164)

Scatter measures the quality of retinotopy and values decrease in development. by Spencer L. Smith (366143)

Image_5_Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue.jpeg by Vinit Upasani (4169677)

<b>Adipose TGR5 deletion promotes hepatic steatosis through decreasing adiponectin secretion in mice</b> by Jiahui Li (646449)

Stx2 and SubAB decrease HGEC viability. by María M. Amaral (439445)

The decrease or inhibition of Hsp90 induced REST degradation. by Raúl Orozco-Díaz (7067624)

“…(D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. …”

Nesfatin-1 decreased excitability of GI-neurons in DVC. by Jing Dong (102657)

Acetylation of histone H3 decreases nucleosome stability. by Alexander Gansen (404272)

Calyculin A-induced decrease of tyrosine-monophosphorylated ERK2 at high cell density. by Noriyuki Kawabata (3391739)

Image5_Immunization of Broiler Chickens With a Killed Chitosan Nanoparticle Salmonella Vaccine Decreases Salmonella Enterica Serovar Enteritidis Load.pdf by Keila Acevedo-Villanueva (10531191)

“…Chitosan nanoparticle (CNP) vaccines can be used to deliver Salmonella antigens orally. We investigated the efficacy of a killed Salmonella CNP vaccine on broilers. …”