Fig 5 - by Lingling Shen (1552231)

Decreased biofilm formation in the Δ<i>tad123</i> mutant cells. by Tra-My Duong-Nu (7300970)

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Digital Microfluidic Platform Based on Printed Circuit Board for Affinity Evaluation of Mertansine Aptamers by Dongliu Xiang (10688647)

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Titanate Nanosheets/Cellulose Composite Showing Improved Crystallinity and Decreased Water Wettability by Gamma-Irradiation by Yaowaluk Tariwong (22630109)

Fig 11 - by Sana Khalid (132742)

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Fig 12 - by Sana Khalid (132742)

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GTDE decreased the expression of the NLRP3 inflammasome and AGEs in the cerebral cortex. by Hui-Chuan Kuo (12368492)

Image_5_Where Are We on the Animal Welfare Map? Using GIS to Assess Stakeholder Diversity and Inclusion.TIFF by Kevin C. Roberts (11828714)

In house finch Harderian glands, we identified ˜90% fewer differentially expressed genes when comparing non-infected controls to MG-infected birds from populations that are more to... by Amberleigh E. Henschen (3257235)

Empirical Bayes estimates of parameter <i>μ</i>. by Guillaume Lingas (9955528)

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Model building procedure. by Guillaume Lingas (9955528)

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Ratio of titers to viral load at the time of peak viral load in cynomolgus macaques infected with Lassa (top) or Ebola (bottom) virus. by Guillaume Lingas (9955528)

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Evolution of target cells TC, productive infected cells I2, refractory cells R and immune effector F. by Guillaume Lingas (9955528)

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BIC of models tested throughout model building. by Guillaume Lingas (9955528)

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Mutagenesis model simulations. by Guillaume Lingas (9955528)

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Pharmacokinetic models and concentrations predictions of treatments considered. by Guillaume Lingas (9955528)

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Parameters distribution using model averaging (Median, 95% CI). by Guillaume Lingas (9955528)

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Individual fits of viral load (plain lines) and viral titers (dashed line) for best model considered (<i>κ</i> = 5). by Guillaume Lingas (9955528)

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