Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor حسب Anat Levit Kaplan (12126567)

"…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"

Stable overexpression of PFKFB3-5 in HEK-293 and U87 cells leads to decreased cell viability and proliferation while leaving transcriptional profile of PFKFB3-1 and -11 unaltered. حسب Ulli Heydasch (11091062)

Su(H) and RBPJ AOS variants decrease DNA binding. حسب Ellen K. Gagliani (11478756)

Cellular uptake of [¹⁴C]docosahexaenoic acid (DHA) by RBECs transfected with MFSD2A siRNA. حسب Takuro Iwao (14636741)

الموضوعات:

Shoot-to-root translocation of GmNN1/FT2a regulates soybean nodulation. حسب Xinxin Li (281237)

Bumblebees were subjected to 5 day exposure to Imidacloprid and/or/none twice daily 670 nm. حسب Michael Barry Powner (11337243)

"…Exposures were for 5 days. Imidacloprid reduced haemocyte numbers (A), which was corrected with twice daily exposure to 670nm light (A). …"

Fig 5 - حسب Samer Sawalha (5890535)

5-HT supplementation induces mitochondrial damage. حسب Li Gao (131516)

Effects of SNPs on the Protein Stability, Increasing or Decreasing. حسب Mirza Jawad Ul Hasnain (8351388)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 12 covariates chosen using subjective feature selection. حسب Dennis Ochola (11626912)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 17 covariates selected after recursive feature selection. حسب Dennis Ochola (11626912)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades حسب Ihab Shawish (13015516)

الموضوعات:

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades حسب Ihab Shawish (13015516)

الموضوعات:

VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. حسب Marek J. Kobylarz (9292599)

PMC exhibits less sensitivity to decreasing signal-to-noise ratio (SNR) حسب Owen Puls (22340344)

Effect of MA-5 on sIBM myoblasts. حسب Yoshitsugu Oikawa (9721356)

App1 decreases the recovery time after amphotericin B treatment. حسب Muhammad Ghaffar (8082002)

Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation - Fig 5 حسب Femke van Diggelen (6499112)

Time series of macrofaunal crustacean abundance at stations in DBO regions 2–5 over the 2010–2019 period. حسب Sue E. Moore (2932644)

Macrofaunal crustacean abundance at time series stations over the 2010–2019 period in DBO regions 2–5 regions. حسب Sue E. Moore (2932644)