Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

Delayed boosting with ALVAC-HIV/AIDSVAX B/E or AIDSVAX B/E increases V1V2-specific IgG concentration and breadth. by LaTonya D. Williams (3140490)

Three Ca_V3.3 variants left-shift the window current, while the A398V completely abolishes the window current. by Yousra El Ghaleb (22075892)

Subjects:

Fold change of TIL subsets in paired TNBCs (N = 12 pts including 10 prim-met, and 2 met-met specimens) using log2 ratio of metastatic versus primary TNBC (n = 10, ●) or second recu... by Ting-Fang He (5210948)

RDV and EIDD2801 EC₅₀ and fold-change in VeroE6-ACE2-TMPRSS2. by Agnieszka M. Szemiel (10196243)

Bacterial load in lung and spleen of binge-drinking mice intranasally infected with decreasing doses of <i>B</i>. <i>thailandensis</i>. by Victor M. Jimenez Jr. (8107853)

Illustrations of the SeqFold2D network and the Stralign dataset. by Xiangyun Qiu (316117)

Genetic correlations in viral load between single and coinfections of CrPV and DCV. by Ryan M. Imrie (15810854)

Interspecific correlations in viral load between single and coinfections of CrPV and DCV. by Ryan M. Imrie (15810854)

Viral loads of CrPV and DCV across host species during single and coinfection. by Ryan M. Imrie (15810854)

Viral loads of CrPV and DCV across DGRP lines during single and coinfection. by Ryan M. Imrie (15810854)

Hedgehog and steroidogenic pathway genes are decreased in <i>Gli3</i>^<i>XtJ</i> testes. by Anbarasi Kothandapani (8934590)

Antibody response elicited by SARS-CoV-2 vaccines. by Chris Davis (647632)

Decreased hypotaurine levels within cells lacking the ADO gene in U251 cells. by Hong Tian (169626)

shRNA mediated silencing of CDK9 decreased proliferation of MM cells. by Su-Lin Lim (8997650)

Decreased Aβ42 halo overlaps with the decreased incidence of DNs in FO treated mice. by Milena Jović (6707702)

“…(E-H) In the FO-treated 5xFAD animals the decreased surface of the Aβ halo overlaps with the decreased incidence of swollen, dystrophic neurites.…”

The I827K substitution destabilizes the 3D fold of E6AP^C-lobe (residues 761–875). by Steven A. Beasley (9099461)

“…<p>(A) The assigned ¹H-¹⁵N-HSQC spectrum of 3.5 mM human E6AP catalytic C-lobe (residues 761–875) using the one-letter amino acid code and residue number according to the human E6AP sequence. …”

Deletion of <i>ERG251-A</i> but not <i>ERG251-B</i> leads to decreased filamentation. by Xin Zhou (54275)

Supplementary data for "Submandibular gland removal decreases avoidance of bitter taste in mice" by Masataka Narukawa (20599511)