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HERVK HML-2 <i>env</i> knockdown decreases IFN-I expression and alters the secretory profile of THP1 monocytes and primary MDMs.
Published 2021“…Green dots represent significant (above blue line) or non-significant decrease in expression of indicated genes in shRNA-Env vs. control shRNA expressing cells (<i>p</i><0.05, fold change >2.0). …”
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Fold change in EC<sub>50</sub> in all polyene resistant lines of <i>Leishmania spp</i>.
Published 2022“…<i>mexicana</i> in DM and E) AmBR-<i>L</i>. <i>infantum</i> in HOMEM. Values higher and lower than 1, indicate a decrease and rise in susceptibility relative to the parental line, respectively. …”
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Characterization of CFDP1-H2A.Z interaction.
Published 2024“…(E) CFDP1 depletion led to a remarkable reduction in chromatin incorporation of exogenously supplied FLAG-H2A.Z compared to control siRNA (con si)-treated cells (<2.5-fold). …”
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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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