بدائل البحث:
nn decrease » _ decrease (توسيع البحث), mean decrease (توسيع البحث), gy decreased (توسيع البحث)
mg decrease » _ decrease (توسيع البحث), we decrease (توسيع البحث), mean decrease (توسيع البحث)
nm decrease » _ decrease (توسيع البحث), we decrease (توسيع البحث), gy decreased (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
5 nm » 5 mm (توسيع البحث), 5 cm (توسيع البحث)
nn decrease » _ decrease (توسيع البحث), mean decrease (توسيع البحث), gy decreased (توسيع البحث)
mg decrease » _ decrease (توسيع البحث), we decrease (توسيع البحث), mean decrease (توسيع البحث)
nm decrease » _ decrease (توسيع البحث), we decrease (توسيع البحث), gy decreased (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
5 nm » 5 mm (توسيع البحث), 5 cm (توسيع البحث)
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81
Mean red and green fluorescence intensity data from three experiments of cyanobacteria.
منشور في 2023الموضوعات: -
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Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance...
منشور في 2021"…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo[1,5-<i>a</i>]pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"
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86
Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance...
منشور في 2021"…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo[1,5-<i>a</i>]pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"
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Oxytocin decreases postsynaptic CeA spontaneous GABAergic transmission and blocks presynaptic alcohol effects.
منشور في 2019"…<p>(A, Top) Representative GABA<sub>A</sub>-mediated sIPSCs of CeA neurons from nondependent and dependent rats prior to (baseline) and during application of oxytocin (500 nM). …"
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89
The decrease or inhibition of Hsp90 induced REST degradation.
منشور في 2019"…<p>(A) Effect of Hsp90α ASO on cell viability. Differentiated SH-SY5Y cells were transfected with different concentrations of Hsp90α ASO. …"
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Functional Plasmonic Microscope: Characterizing the Metabolic Activity of Single Cells via Sub-nm Membrane Fluctuations
منشور في 2024"…A low-concentration dose showed a reduced fluctuation frequency with consistent fluctuation amplitudes, while the high-concentration dose showcased a decreasing trend in both cases. …"
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96
Functional Plasmonic Microscope: Characterizing the Metabolic Activity of Single Cells via Sub-nm Membrane Fluctuations
منشور في 2024"…A low-concentration dose showed a reduced fluctuation frequency with consistent fluctuation amplitudes, while the high-concentration dose showcased a decreasing trend in both cases. …"
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97
Functional Plasmonic Microscope: Characterizing the Metabolic Activity of Single Cells via Sub-nm Membrane Fluctuations
منشور في 2024"…A low-concentration dose showed a reduced fluctuation frequency with consistent fluctuation amplitudes, while the high-concentration dose showcased a decreasing trend in both cases. …"
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98
Discovery of Novel Acridane-Based Tubulin Polymerization Inhibitors with Anticancer and Potential Immunomodulatory Effects
منشور في 2022"…The most potent compound <b>NT-6</b> exhibited high tubulin polymerization inhibitory activity (IC<sub>50</sub> = 1.5 μM) and remarkable antiproliferative potency against four cancer cell lines with an average IC<sub>50</sub> of 30 nM, better than colchicine and the hit compound <b>1f</b> (IC<sub>50</sub> of 65 and 126 nM, respectively). …"
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99
Discovery of Novel Acridane-Based Tubulin Polymerization Inhibitors with Anticancer and Potential Immunomodulatory Effects
منشور في 2022"…The most potent compound <b>NT-6</b> exhibited high tubulin polymerization inhibitory activity (IC<sub>50</sub> = 1.5 μM) and remarkable antiproliferative potency against four cancer cell lines with an average IC<sub>50</sub> of 30 nM, better than colchicine and the hit compound <b>1f</b> (IC<sub>50</sub> of 65 and 126 nM, respectively). …"
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100