Showing 81 - 100 results of 66,613 for search '(( 5 ((nn decrease) OR (a decrease)) ) OR ((( a step decrease ) OR ( e fold decrease ))))', query time: 0.92s Refine Results
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    Effective contact rate over time for the different modelling scenarios considered: fixed, continuously increasing, continuously decreasing and with a step-decrease. by Joshua Looker (21390948)

    Published 2025
    “…<p>Effective contact rate over time for the different modelling scenarios considered: fixed, continuously increasing, continuously decreasing and with a step-decrease.</p>…”
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    Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa by Andrej Emanuel Cotman (5203904)

    Published 2023
    “…Starting from DNA gyrase inhibitor <b>1</b>, we identified compound <b>27</b>, featuring a 10-fold improved aqueous solubility, a 10-fold improved inhibition of topoisomerase IV from A. baumannii and P. aeruginosa, a 10-fold decreased inhibition of human topoisomerase IIα, and no cross-resistance to novobiocin. …”
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    Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

    Published 2024
    “…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”
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    Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

    Published 2024
    “…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”
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    Analysis of Drugs in Whole Blood by Paper Spray Mass Spectrometry with Integrated Solid-Phase Extraction by Greta Ren (9974860)

    Published 2025
    “…The dry SPE holder is “snapped” in the paper spray cartridge. A variety of parameters were optimized to improve manufacturing and the performance of the device, including waste pad substrates, SPE sorbents, and binders; the size of the SPE compartment; the amount of SPE; a water wash step; and blood volume. …”