Table_1_The transcriptome response of astronaut leukocytes to long missions aboard the International Space Station reveals immune modulation.docx by Daniel Stratis (16415880)

“…</p>Methods<p>Fourteen male and female astronauts with ~6-month- long missions aboard the International Space Station (ISS) had 10 blood samples collected throughout the three phases of the study: one pre-flight (PF), four in-flight (IF) while onboard the ISS, and five upon return to Earth (R). We measured gene expression through RNA sequencing of leukocytes and applied generalized linear modeling to assess differential expression across all 10 time points followed by the analysis of selected time points and functional enrichment of changing genes to identify shifts in biological processes.…”

New Steric Hindrance Approach Employing the Hybrid Ligand 2-Aminomethylpiperidine for Diminishing Dynamic Motion Problems of Platinum Anticancer Drug Adducts Containing Guanine Der... by Hing C. Wong (572439)

“…However, at pH 9.5, where the 5‘-GMP N1H was largely deprotonated, the NMR spectrum and the ∼280 nm CD peak both revealed that the ΛHT form had decreased. …”

Expanding HAART Treatment to All Currently Eligible Individuals under the 2008 IAS-USA Guidelines in British Columbia, Canada by Viviane D. Lima (118005)

“…In the 50% scenario, in 5 years, DALY decreased by 53% corresponding to 4155 averted DALYs, and in 25 years it decreased by 66% corresponding to 5837 averted DALYs. …”

Evolutionary assembly drives the diversity of assembly outcomes. by Gui Araujo (22170819)

“…The connectance of invading species was drawn from a uniform distribution between 0.05 and 0.5. In speciation, offspring species had up to 5 interactions differing from the parent species, chosen randomly (, see Methods). …”

Linking surveillance and clinical data for evaluating trends in bloodstream infection rates in neonatal units in England by Caroline Fraser (5920379)

“…Equivalent proportions for babies born before 32 weeks of gestation were 5.0%, 4.8%, 2.9% and 5.9%. The proportion of babies who linked to a BSI decreased by 7.5% each year (95% confidence interval [CI]: -14.3%, -0.1%) using deterministic and probabilistic linkage but was stable using clinical records of BSI or deterministic linkage alone.…”

Figure 8 by Andy M. Reynolds (358209)

“…Mean times do not change significantly when the length scale <i>L</i> is increased or decreased by a factor of 2. …”

Table_1_Incidence trends and disparities in Helicobacter pylori related malignancy among US adults, 2000–2019.DOCX by Yafang Lai (14184500)

“…For gastric NHL, the decreasing incidence were significantly slower for those aged 20–64 years (AAPC, −1.5% [95% CI, −1.9–1.1%]) and Black individuals (AAPC, −1.3% [95% CI, −1.9–1.1%]). …”

Endometriosis Is Associated with Rare Copy Number Variants by Rakesh Chettier (73475)

“…Three CNV's passed a genome-wide P-value threshold of 9.3×10⁻⁴; a deletion at <i>SGCZ</i> on 8p22 (P = 7.3×10⁻⁴, OR = 8.5, Cl = 2.3–31.7), a deletion in <i>MALRD1</i> on 10p12.31 (P = 5.6×10⁻⁴, OR = 14.1, Cl = 2.7–90.9), and a deletion at 11q14.1 (P = 5.7×10⁻⁴, OR = 33.8, Cl = 3.3–1651). …”

Inhibition of inflammation in the brain of P. berghei-infected mice with ECM after treatment. by Nana O. Wilson (399957)

“…<p>(A) The number of intravascular leukocytes per mm2 of brain area was markedly decreased after treatment. …”

Age-Related Differences in Test-Retest Reliability in Resting-State Brain Functional Connectivity by Jie Song (60883)

“…By comparing the test-retest reliability of RSFC with and without GSR across scans, we found significantly higher proportion of reliable connections in both groups without GSR, but decreased stability. …”

Data_Sheet_1_Impacts of Heart Failure and Physical Performance on Long-Term Mortality in Old Patients With Chronic Kidney Disease.pdf by Shuo-Chun Weng (546159)

“…Rockwood frailty and HF were both significantly associated with CKD stages. After a mean follow-up period of 3.1 ± 2.1 years, 44 patients died, and a crude analysis showed that stage 4, stage 5 CKD, low HGS, and Rockwood frailty index were associated with mortality. …”

Efficacy of disinfection using two different protocols. by Tina Rocktäschel (9909867)

“…<p>The figure illustrates the reduction of bacterial numbers in %. (A) Decrease in bacterial numbers on the right hand determined in phase 1 and phase 2 of the study. …”

Crystallization, thermal and mechanical behavior of oligosebacate plasticized poly(lactic acid) films by Erika Martins Inácio (6044024)

“…DSC revealed the decrease in the Tg of PLA films with addition of the oligomer and a partial immiscibility. …”

Crystallization, thermal and mechanical behavior of oligosebacate plasticized poly(lactic acid) films by Erika Martins Inácio (6044024)

“…DSC revealed the decrease in the Tg of PLA films with addition of the oligomer and a partial immiscibility. …”

Downregulation of detoxification genes in villi lacking functional pRb and/or E2F1-2-3 proteins. by Maria Teresa Sáenz Robles (201330)

“…Samples were normalized against an endogenous control (Adh and/or Rpl5). c) Cyp3A protein levels decrease in samples lacking pRb. …”

Data_Sheet_1_Tape-Strip Proteomic Profiling of Atopic Dermatitis on Dupilumab Identifies Minimally Invasive Biomarkers.XLSX by Helen He (345966)

“…Using criteria of fold-change>1.5 and FDR < 0.05, 136 proteins significantly decreased after dupilumab treatment, corresponding to an overall mean improvement of 66.2% in the lesional vs. non-lesional AD proteome. …”

Upregulation of Innate Antiviral Restricting Factor Expression in the Cord Blood and Decidual Tissue of HIV-Infected Mothers by Nátalli Zanete Pereira (427812)

“…The mRNA and protein expression levels of antiviral factors were then evaluated. We observed a significant increase in the mRNA expression levels of antiviral factors in MNCs from HIV-infected mothers and CB, including the apolipoprotein B mRNA-editing enzyme 3G (A3G), A3F, tripartite motif family-5α (TRIM-5α), TRIM-22, myxovirus resistance protein A (MxA), stimulator of interferon (IFN) genes (STING) and IFN-β, compared with the levels detected in uninfected (UN) mother-CB pairs. …”

Data_Sheet_1_Spatiotemporal patterns of gross ecosystem product across China's cropland ecosystems over the past two decades.pdf by Jiaying Zhang (585596)

“…The majority of provinces had an increasing trend in GEP, yet some developed provinces, e.g., Beijing and Shanghai, showed a decreasing trend. Furthermore, we evaluated the impacts of social-economic and natural factors on changes in GEP. …”

Effects of miR21 deletion on ECM expression in aorta of the miR21 endothelial-specific KO mice. by Xing-Yi Zhang (391076)

“…<i>n</i> = 5 for each group, *<i>p</i><0.05. (<b>B</b>) Collagen I mRNA is significantly decreased in the KO group. …”

Heterogeneous mass balance of selected Glaciers in the Hindu Kush, Karakoram, and Himalaya between 2000 and 2018 by Huma Hayat (14614260)