Obesity and leptin resistance in <i>Bbs4^−/−</i> mice are rescued by <i>LAP-BBS4</i>. by Xitiz Chamling (390467)

“…<p>A) 10 mice per group <b>(</b>5 male and 5 female) mice were weighed every month to 6 months of age. …”

AR activation causes cell cycle arrest and senescence in PC3 cells. by Yelena Mirochnik (179447)

“…(<b>E</b>) Senescent cells were counted on the digital images of 5 random fields using Image Tool 3.00 software (UTHSCSA); means of three independent experiments with S.D.M. are shown. …”

Evaluation of retinal and choroidal microvascular changes in patients who received hydroxychloroquine by optical coherence tomography angiography by Esat Cinar (10366844)

“…The macular flow area (superficial, deep, and choriocapillaris), superficial and deep vessel density, foveal avascular zone area, central foveal thickness, and subfoveal choroidal thickness parameters were measured by optical coherence tomography angiography. Results: The mean age of the 28 patients who received hydroxychloroquine and the 28 age-matched controls was 45.5 ± 11.1 years (range: 29-70 years) and 44.5 ± 13.9 years (range: 28-70 years), respectively. …”

High diversity of functional <i>KIR</i> haplotypes in Ghana. by Paul J. Norman (234033)

“…<p>A. Cumulative frequency plot of the high-resolution <i>KIR</i> haplotypes, which have been added in order of decreasing frequency. …”

GAS DNase Sda1 promotes resistance to macrophage killing. by Satoshi Uchiyama (18224)

“…Data shown in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002736#ppat-1002736-g005" target="_blank">Fig. 5C</a> is one out of three representative experiments each done in triplicate and presented as mean ± SEM (A and B) ± SD (C). * <i>P</i><0.05 ** <i>P</i><0.01.…”

Early ¹⁸F-FDG PET/CT Evaluation Shows Heterogeneous Metabolic Responses to Anti-EGFR Therapy in Patients with Metastatic Colorectal Cancer by Erik J. van Helden (2794642)

“…Dichotomised metabolic data of the sum of all or ≤ 5 lesions had a concordance with clinical benefit of 89% using SUL_max or SUL_peak, and 100% using TLG. …”

Image_1_Residual effects of combined vibratory and plantar stimulation while seated influences plantar pressure and spatiotemporal gait measures in individuals with Parkinson’s dis... by Warongporn Phuenpathom (13231437)

“…</p>Results<p>The FOG shoes group showed significantly decreased %FOG (81.5 ± 28.9% vs. 6.8 ± 22.1%, p < 0.001), plantar pressure in the heel-strike (47.8 ± 43.7% vs. 4.3 ± 9.8%, p < 0.001), plantar pressure in the push-off (57.7 ± 59.6% vs. 6.2 ± 11.6%, p < 0.001), force time integral (FTI) (40.9 ± 32.5% vs. 6.6 ± 17.3%, p < 0.001), and decreased heel contact time (19.3 ± 12.3% vs. 22.7 ± 32.5%, p < 0.001) when compared to the sham group. …”

Data_Sheet_1_Residual effects of combined vibratory and plantar stimulation while seated influences plantar pressure and spatiotemporal gait measures in individuals with Parkinson’... by Warongporn Phuenpathom (13231437)

“…</p>Results<p>The FOG shoes group showed significantly decreased %FOG (81.5 ± 28.9% vs. 6.8 ± 22.1%, p < 0.001), plantar pressure in the heel-strike (47.8 ± 43.7% vs. 4.3 ± 9.8%, p < 0.001), plantar pressure in the push-off (57.7 ± 59.6% vs. 6.2 ± 11.6%, p < 0.001), force time integral (FTI) (40.9 ± 32.5% vs. 6.6 ± 17.3%, p < 0.001), and decreased heel contact time (19.3 ± 12.3% vs. 22.7 ± 32.5%, p < 0.001) when compared to the sham group. …”

X-ChIP based affinity purification provides the most inclusive analysis of nucleoid associated proteins. by Nina Rajala (693865)

“…Samples were analysed (in duplicate for TwinkleFLAG + XL, otherwise in triplicate) by shotgun mass spectrometry using a Q Exactive Orbitrap. To again identify potentially interesting proteins we compared all 4 generated lists simultaneously using Venny, similar as in Figs. …”

<i>GSK-3β</i> −/− palatal phenotype. by Emily R. Nelson (247130)

“…The area of the palatine bones displayed a 48 percent decrease in the <i>GSK-3β</i> null embryos at both e17.0 and e18.5. …”

<i>Blastocystis</i> effects on zymosan (ZG) stimulation of THP1-Blue monocytes. by Joshua D. W. Teo (523218)

“…<p>Detection of SEAP activity from cell culture supernatants of THP1-Blue monocytes incubated with various conditions. A, B. Both <i>Blastocystis</i> ST7-B and ST4-WR1 significantly inhibits ZG-induced activation of THP1-Blue monocytes, as observed in the decrease in SEAP activity. …”

Hfq melts the stem structure of but does not promote annealing by Véronique Arluison (25027)

“…Addition of Hfq results in gradual FRET decrease (average lifetime ∼15 min). () Average melting times were measured as a function of Hfq concentration (as plotted) and it decreases to ∼4 min in saturating concentrations of Hfq. () Hfq does not promote annealing of I and II. () Emission spectra of the mixture of 25 nM Cy3-I and 62.5 nM Cy5.5-II in T50 buffer without (black lines), after incubating the sample for 5 min without Hfq, and then with 28 nM of Hfq (blue lines).…”

Image_1_Urocortin-2 Prevents Dysregulation of Ca2+ Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion.tif by Alejandro Domínguez-Rodríguez (279819)

“…Moreover, Ucn-2 recovered the amplitude of [Ca²⁺]_i transient and modulated the expression of several proteins related to [Ca²⁺]_i homeostasis, such as TRPC5 and Orai1 channels. Using Neonatal Rat Ventricular Myocytes (NRVM) we demonstrated that Ucn-2 blunted I/R-induced Store Operated Ca²⁺ Entry (SOCE), decreased the expression of TRPC5 and Orai1 as well as their interaction in reperfusion.…”

Image_2_Urocortin-2 Prevents Dysregulation of Ca2+ Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion.tif by Alejandro Domínguez-Rodríguez (279819)

“…Moreover, Ucn-2 recovered the amplitude of [Ca²⁺]_i transient and modulated the expression of several proteins related to [Ca²⁺]_i homeostasis, such as TRPC5 and Orai1 channels. Using Neonatal Rat Ventricular Myocytes (NRVM) we demonstrated that Ucn-2 blunted I/R-induced Store Operated Ca²⁺ Entry (SOCE), decreased the expression of TRPC5 and Orai1 as well as their interaction in reperfusion.…”

Endothelial Cell and Platelet Bioenergetics: Effect of Glucose and Nutrient Composition by Brian D. Fink (157191)

“…Acute or overnight exposure of confluent BAE cells to glucose concentrations from 5.5 to 25 mM did not enhance or change the rate of oxygen consumption (OCR) under basal conditions, during ATP synthesis, or under uncoupled conditions. …”

Direct maintenance of acinar cell activity in lacrimal glands (LGs) by orally administrated royal jelly. by Sachiko Inoue (3621764)

“…<p>A: Effects of RJ on decreased tear secretion after postganglionic denervation (PGD; six mice). …”

Comparison of PCs simple spike rate changes and spike regularity in response to light activation of PCs, MLIs and GCs. by Wolfgang Kruse (619565)

“…Twelve out of 25 cells showed a decrease in PC simple spike rate after GC light activation. …”

Injury index values for Chinook salmon. by Brandon M. Casper (318466)

“…<p>The injury index values for Exposure 1 and 2 to which Chinook salmon were exposed. There was a significant decrease in RWI scores from day 2 to day 5 in Exposure 1 fish (solid blue diamonds), suggesting that this is when healing is beginning to occur. …”

Variations in Rg with time. by Alka Srivastava (561974)

“…In contrast, in systems with charged termini (panels A, B, E, F, I and J), Rg is not constant and three possible types of change (decrease, increase, and large variations) are observed.…”

Genes whose expression was regulated by riluzole in the WM793 cell line using the Human TGFβ/BMP Signaling Pathway RT² Profiler™ PCR Array. by Walid Abushahba (303111)