Novel Polyfermentor Intestinal Model (PolyFermS) for Controlled Ecological Studies: Validation and Effect of pH by Annina Zihler Berner (478117)

“…Furthermore, the metabolic response to a decrease of pH from 5.7 to 5.5, applied to balance the high fermentative activity in inoculum reactors, was studied. …”

Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy by Maria Xilouri (264240)

“…In both PC12 and SH-SY5Y cycling cells, induction of A53T ASYN evoked a significant decrease in lysosomal degradation, largely due to CMA impairment. …”

Distinct context-specific interactions regulate <i>pntP2</i> transcription across the eye field. by Chudong Wu (9708019)

“…In <i>pnt</i>^<i>p2</i> discs (D) relative to wild type (C), an increased and broader peak of <i>pntP2</i> transcripts was detected in and immediately posterior to the MF while a decrease was seen in the posterior half of the disc. …”

Low concentrations of metformin inhibited Erk and mTOR phosphorylation and increased Akt phosphorylation of CD133⁺ pancreatic cancer cells. by Shanmiao Gou (411281)

“…Expression of AMPKα, Akt, Erk1/2, and mTOR and phosphorylation of CD133⁺ cells were evaluated by western blotting and the results were quantified using ImageJ V.1.46r (National Institutes of Health). Significant decreases of phospho-ERK1/2 and phospho-mTOR expression and a significant increase of phospho-Akt expression were observed in the metformin treated cells. …”

Intracerebral ventricular infusion of IL-1β receptor antagonist prevents blood-brain-barrier disruption induced by Nef expression in the rat hippocampus. by Jocelyn Rivera (2276668)

“…<p><b>(A)</b> Immunofluorescence of claudin-5: the green represents the tight junction claudin-5, while the blue represents the nucleus of the cells. …”

Image1_An ex-vivo model for the biomechanical assessment of cement discoplasty.PDF by Salim Ghandour (13582540)

“…A decrease of 51.5% in segment stiffness was found after injury, as expected. …”

Reduced insulin/IGF-1-like signaling protects against age-dependent protein insolubility and aggregation. by Della C. David (244107)

“…<p>(A) Sypro Ruby staining revealed a decrease in overall age-dependent protein insolubility in <i>gon-2(−)</i>/gonad-less animals treated with <i>daf-2</i> RNAi compared to control RNAi (1.6-fold compared to a 3.6-fold increase with age, quantified in the red outlined areas). …”

Genes differentially expressed in response to heat-shock-induced overexpression of , grouped according to functional classes by Ronny Leemans (54731)

“…Positive values indicate that the relative expression level of a gene is increased (upregulated) following overexpression and negative values indicate a decrease (downregulated). …”

Predicted upstream regulators. by Opas Traitanon (756970)

“…Please see Table H in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0216300#pone.0216300.s005" target="_blank">S5 File</a> for complete information.…”

AZ2.0 Scripts & Code by Binay Panda (768771)

“…The updated genome assembly (v2.0) yielded 3- and 3.5-fold increase in N50 and N75, respectively; 2.6-fold decrease in the total number of scaffolds; 1.25-fold increase in the number of valid transcriptome alignments; 13.4-fold less mis-assembly and 1.85-fold increase in the percentage repeat, over the earlier assembly (v1.0). …”

The expression of PPARγ protein is dependent on MST2 and SAV1. by Byoung Hee Park (334128)

“…(E) The degradation of PPARγ protein was proteasome-dependent. The decrease of PPARγ protein induced by knock-down of SAV1 expression was inhibited by 5 µM lactacystin, a proteasome inhibitor.…”

Performance evaluation of an alternative composite for urban systems and low-cost housing by Paulo Gedeão Barroso Gomes Júnior (12835065)

“…In general, there was an increase in mechanical strength with curing and a decrease with the insertion of sludge. The material showed low degradation in the wear tests. …”

Internalization. by Aliaa H. Abdelhakim (628663)

“…<p><b>A</b>. Image of three particles that uncoat after addition of fluorescently labeled m159 antibody to the medium. …”

Temporal dynamics of aquatic insects and oligochaetes in tropical springs by Luiza Pedrosa Guimarães (18157480)

“…Seasonality and predictability were high for both climate variables: accumulated rainfall and average air temperature. We found a greater abundance of macroinvertebrates in the dry period, mostly due to the increase in aquatic insects following a decrease in the abundance of oligochaetes. …”

Transcriptional Mediators Kto and Skd Are Involved in the Regulation of the IMD Pathway and Anti-<em>Plasmodium</em> Defense in <em>Anopheles gambiae</em> by Yang Chen (9737)

“…RNAi-mediated depletion of Kto and Skd in the <em>Anopheles gambiae</em> cell line L5-3 resulted in a decrease in the transcript abundance of <em>Cec1,</em> which is controlled by the IMD pathway. …”

The role of energy diversification in the average income and pollution intensity of OECD economies by Francisco Triguero-Ruiz (22673619)

“…Results indicate that greater diversification of the energy mix is associated with reductions in pollution intensity (≈2.6% short run and ≈9.6% long run per unit decrease in the index), while also supporting higher per-capita income (≈1.3% and ≈5.7%). …”

Impact of KCNE1 expression on WT Kv7.1 and mutant R228C. by Liora Shamgar (44235)

“…Currents were evoked by a train of step depolarization to +30 mV. Similar results have been obtained in 5 other cells.…”

Sevoflurane alters the relative proportions of diffuse-type versus cluster-type filopodia in DIV9 developing mouse hippocampal neurons. by Jeffrey H. Zimering (3148962)

“…<p>(A) 3% sevoflurane for four hours on DIV7 caused an increase in diffuse-type and a decrease in cluster-type filopodia two days later compared to control unexposed hippocampal neurons. …”

FIGURE 1 from Immunologic Signatures of Peripheral Blood T Cells Reveal the Outcome of p53MVA Vaccine and Pembrolizumab Treatment in Patients with Advanced Ovarian Cancer by Ferdynand J. Kos (17683564)

“…Relative changes in tumor sizes derived from radiological evaluations (<b>A</b>) show that 3/28 PR patients had a decrease of 76.4%, 93.3%, and 59.5% in tumor burden (irRECIST). …”

Altered collagen in CypB–knockout mice. by Jae Won Choi (256367)

“…Secreted collagen from the supernatant was electropheresed on 5% SDS-PAGE and detected by Western Blotting. Type I collagen from mutant animals demonstrated a subtle but reproducible decrease in migration compared to wild type. …”