Hyperlipidemia-Associated Renal Damage Decreases Klotho Expression in Kidneys from ApoE Knockout Mice by Cristina Sastre (503532)

“…Hyperlipidemia accelerates the progression of renal damage, but the mechanisms of the deleterious effects of hyperlipidemia remain unclear.</p><p>Methods</p><p>We evaluated whether hyperlipidemia modulates Klotho expression in kidneys from C57BL/6 and hyperlipidemic apolipoprotein E knockout (ApoE KO) mice fed with a normal chow diet (ND) or a Western-type high cholesterol-fat diet (HC) for 5 to 10 weeks, respectively.…”

Gramine Derivatives Targeting Ca²⁺ Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases by Rocío Lajarín-Cuesta (1530580)

“…Hence, we propose this multitarget approach as a new and promising strategy for the treatment of neurodegenerative diseases.…”

FEF inactivation decreased ipsilesional and contralesional microsaccade peak velocities, both before and after cue onset. by Tyler R. Peel (2935848)

“…<p>(<b>A</b>) Unilateral (left) FEF inactivation reduced peak velocity for contralesional microsaccades independently of amplitude in our example monkey DZ and also decreased peak velocities for ipsilesional microsaccades. …”

S3 Data - by Dwight D. Harris (14484648)

“…Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). …”

S2 Data - by Dwight D. Harris (14484648)

“…Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). …”

S1 Data - by Dwight D. Harris (14484648)

“…Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). …”

S4 Data - by Dwight D. Harris (14484648)

“…Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). …”

<i>PGRP-LC</i> knockdown in gut mitigates the decrease in lifespan caused by heat-killed <i>A</i>. <i>persici</i>. by Taro Onuma (15195377)

Filamentation induced by DTPA is associated with a decrease in Nrg1 protein level, and requires the cAMP-PKA pathway and the kinase Sok1. by Elizabeth J. Polvi (3163500)

DataSheet1_Calmodulin mutations affecting Gly114 impair binding to the NaV1.5 IQ-domain.docx by Malene Brohus (840080)

“…We therefore hypothesized that the G114R variant specifically would interfere with Na_V1.5 binding. …”

Table_1_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.docx by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”

Image_3_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.tif by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”

Image_1_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.tif by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”

Image_2_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.tif by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”

A647D mutation decreases I_Na of WT and P1332L when co-expressed. by Jie Liu (15128)

Supplementary Material for: Clinical Implications of Decreased Computed Tomography Value after Ramucirumab in Advanced Gastric Cancer by Izawa N. (6834062)

“…<b><i>Objectives:</i></b> This study aimed to evaluate whether a decrease of computed tomography (CT) value for tumors serves as a predictive marker in patients with advanced gastric cancer (aGC) who have undergone chemotherapy with vascular epithelial growth factor receptor 2 inhibitor (ramucirumab). …”

Supplementary Material for: Enhanced Recovery after Surgery for Radical Cystectomy Decreases Postoperative Complications at Different Times by Lannes F. (11465377)

“…<b><i>Methods:</i></b> We performed a retrospective monocentric study using prospectively maintained databases including all patients treated by radical cystectomy between January 2015 and July 2019. …”

Data_Sheet_1_Risk of psychological distress by decrease in economic activity, gender, and age due to COVID-19: A multinational study.PDF by Minji Kim (1722313)

“…Moreover, countries with lower HDI showed a higher prevalence of decrease in economic activity, especially at lower education levels.…”

Average split and overall race times (HH:MM:SS). by Beat Knechtle (5504402)

“…</p><p>Aim</p><p>The aim of the study was to examine potential sex differences in the three split disciplines by age groups in 5-year intervals in a very large data set of IRONMAN^® age group triathletes.…”

PRMT5 stabilizes vCyclin protein expression in a manner dependent on its methyltransferase activity. by Danping Niu (10912688)

“…<p>(A-B) Effect of PRMT5 on vCyclin expression. First, HEK293T cells were cotransfected with fixed amounts of vCyclin expression plasmid and increasing amounts of PRMT5 expression plasmids. …”