Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Increased reactive oxygen species (ROS) production and decreased mitochondrial membrane potential in <i>Tet-mev-1</i> hepatocytes. by Tadashi Moro (844328)

Shoot-to-root translocation of GmNN1/FT2a regulates soybean nodulation. by Xinxin Li (281237)

Functional Plasmonic Microscope: Characterizing the Metabolic Activity of Single Cells via Sub-nm Membrane Fluctuations by Suraj D. Khochare (18288990)

“…A low-concentration dose showed a reduced fluctuation frequency with consistent fluctuation amplitudes, while the high-concentration dose showcased a decreasing trend in both cases. …”

Functional Plasmonic Microscope: Characterizing the Metabolic Activity of Single Cells via Sub-nm Membrane Fluctuations by Suraj D. Khochare (18288990)

“…A low-concentration dose showed a reduced fluctuation frequency with consistent fluctuation amplitudes, while the high-concentration dose showcased a decreasing trend in both cases. …”

Functional Plasmonic Microscope: Characterizing the Metabolic Activity of Single Cells via Sub-nm Membrane Fluctuations by Suraj D. Khochare (18288990)

“…A low-concentration dose showed a reduced fluctuation frequency with consistent fluctuation amplitudes, while the high-concentration dose showcased a decreasing trend in both cases. …”

TLR4 receptor inhibition decreased ranibizumab and aflibercept mediated CCL2, CCL5, and CX3CL1 mRNA and protein levels in HCAECs. by Clare Arnott (2557705)

Effect of perfusion with VEGF121 on outflow facility. by Tomokazu Fujimoto (709192)

Four-fold decrease in [H⁺]_e shifted GLT-1a E_rev by −18 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

“…Arrows show GLT-1a E_rev shifts. <b>(C)</b> Average GLT-1 E_rev shifts at 37.5 μM and 600 μM are approximately equal when [H⁺]_e was decreased from 40 to 10 nM.…”

Effect of MA-5 on sIBM myoblasts. by Yoshitsugu Oikawa (9721356)

Bumblebees were subjected to 5 day exposure to Imidacloprid and/or/none twice daily 670 nm. by Michael Barry Powner (11337243)

“…Exposures were for 5 days. Imidacloprid reduced haemocyte numbers (A), which was corrected with twice daily exposure to 670nm light (A). …”

eIF5a is up-regulated in unruptured AAAs and decreased in ruptured AAAs. by Dong Ma (584680)

Subjects:

Scatter measures the quality of retinotopy and values decrease in development. by Spencer L. Smith (366143)

Longer exposure to MPA increases the CD4/CD8 ratio, decreases CD8+ T-cell frequency, and increases the density of the CCR5 coreceptor on CD4+ and CD8+ T-cells. by Michelle F. Maritz (5146730)

The decrease or inhibition of Hsp90 induced REST degradation. by Raúl Orozco-Díaz (7067624)

“…<p>(A) Effect of Hsp90α ASO on cell viability. Differentiated SH-SY5Y cells were transfected with different concentrations of Hsp90α ASO. …”

Stx2 and SubAB decrease HGEC viability. by María M. Amaral (439445)

Nesfatin-1 decreased excitability of GI-neurons in DVC. by Jing Dong (102657)

Acetylation of histone H3 decreases nucleosome stability. by Alexander Gansen (404272)

Calyculin A-induced decrease of tyrosine-monophosphorylated ERK2 at high cell density. by Noriyuki Kawabata (3391739)

CCN3 protein decreases β-cell proliferation. by Renée Paradis (326111)