Supplementary file 1_Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.docx by Ningning Chen (509273)

“…Moreover, microRNAs (miRNAs) are an important class of gene expression regulators. We found that the upregulated hsa-miR-33a-5p repressed IGFBP5 translation by forming a silencing complex with Argonaute protein 2 (AGO2) in a real-ambient PM exposure system, which further led to the suppression of the ERK1/2-SOD2 signaling pathway and increased levels of ROS.…”

Supplementary Material for: Longitudinal Decrease in Left Ventricular Size with Age: Impact on Mortality and Cardiovascular Hospitalization by figshare admin karger (2628495)

“…This study investigated clinical characteristics and outcomes associated with longitudinal decreases in LV size in this population. Methods: We analyzed echocardiographic data from 6,232 adults with normal baseline left ventricular end-diastolic diameter (LVEDD), with a mean interval of 4.8 years between baseline and follow-up echocardiograms. …”

FA decrease in 5STS impaired participants. by Charlotte Bernard (433013)

ATM/ATR substrates with synergistic increase and decrease in phosphorylation by FGF21/insulin co-treatment. by Darwin V. Lee (653885)

ATRA decreases mRNA expression of HO-1, GCLM and x-CT and lowers GSH level in BTZ-treated cells. by A. L. Furfaro (2587792)

The specific TH activity of the cell lysates after transfection with wild-type TH, mutant TH^A304V, and TH^R453H. by Zhan-fang Sun (624794)

“…<p>Compared with the wild-type, the specific TH activity with the mutant TH^A304V and TH^R453H were both significantly decreased (<i>P</i><0.05). …”

Effects of vidarabine, V2E, V3E and V5E on cardiac fibrosis. by Kenji Suita (750993)

“…<p>We examined the effects of chronic ISO infusion (60 mg/kg/day for 1 week) via osmotic mini-pumps in WT mice with/without vidarabine (Vida), V2E, V3E or V5E on cardiac fibrosis by means of Masson-trichrome staining. …”

Decreased levels of PRMT1 alters BRCA1 promoter binding <i>in vivo.</i> by Irene Guendel (173419)

Data_Sheet_1_The Risky Decrease of Fishing Reference Points Under Climate Change.docx by Morgane Travers-Trolet (548023)

“…The model was first parameterized and run to fit the historical situation (2000–2009) and then used to assess the ecosystem state for the 2050–2059 period, using two contrasting climate change scenarios (RCP 4.5 and RCP 8.5). For each condition, a monospecific MSY estimation routine was performed by varying species fishing mortality independently and allowed estimation of reference points for each species. …”

Treatment with rSFRP4 results in decreased migration and increased adhesion of ovarian cancer cells. by Caroline E. Ford (289563)

Blocking C5L2 decreased C5a-primed neutrophils expression of membrane-bound PR3 (mPR3). by Jian Hao (160736)

The effect of bicarbonate on secretagogue stimulated zymogen activation decreased by PKA inhibition using myristolated PKI. by Thomas R. Kolodecik (297507)

The effect of bicarbonate on secretagogue stimulated zymogen activation is decreased by PKA inhibition using H89. by Thomas R. Kolodecik (297507)

ATRA decreases the binding of Nrf2 to ARE sequences in the promoter regions of HO-1, GCLM and x-CT in BTZ-treated cells. by A. L. Furfaro (2587792)

Knockdown of PABPC1 with siRNA decreases PSA luciferase activity and PSA protein levels. by Kurtis Eisermann (95302)

Combined decitabine and Taxol decreases MCF-7/Taxol cells proliferation and can improve their chemosensitivity. by Weihua Gong (471435)

Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

Subjects:

Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

Subjects:

Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

Subjects:

Hydrogen-Bonding Trends in a Bithiophene with 3- and/or 4‑Pyridyl Substituents by Alison M. Costello (16456762)

“…We found that with the 5-(3-pyridyl)-5′-(4-pyridyl)-isomer, the 4-pyridyl ring interacted with electrophiles and protons more strongly. …”