Hyperlipidemia-Associated Renal Damage Decreases Klotho Expression in Kidneys from ApoE Knockout Mice by Cristina Sastre (503532)

“…Hyperlipidemia accelerates the progression of renal damage, but the mechanisms of the deleterious effects of hyperlipidemia remain unclear.</p><p>Methods</p><p>We evaluated whether hyperlipidemia modulates Klotho expression in kidneys from C57BL/6 and hyperlipidemic apolipoprotein E knockout (ApoE KO) mice fed with a normal chow diet (ND) or a Western-type high cholesterol-fat diet (HC) for 5 to 10 weeks, respectively.…”

Gramine Derivatives Targeting Ca²⁺ Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases by Rocío Lajarín-Cuesta (1530580)

“…Hence, we propose this multitarget approach as a new and promising strategy for the treatment of neurodegenerative diseases.…”

FEF inactivation decreased ipsilesional and contralesional microsaccade peak velocities, both before and after cue onset. by Tyler R. Peel (2935848)

“…<p>(<b>A</b>) Unilateral (left) FEF inactivation reduced peak velocity for contralesional microsaccades independently of amplitude in our example monkey DZ and also decreased peak velocities for ipsilesional microsaccades. …”

Length-Dependent Convergence and Saturation Behavior of Electrochemical, Linear Optical, Quadratic Nonlinear Optical, and Cubic Nonlinear Optical Properties of Dipolar Alkynylruthe... by Bandar Babgi (2360545)

“…The syntheses of <i>trans</i>-[Ru{4,4′-CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>19</b>), <i>trans</i>-[Ru{4,4′,4′′-CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>20</b>), <i>trans</i>-[Ru{4,4′,4′′,4′′′-CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppe)₂] (<b>21</b>), <i>trans</i>-[Ru{4,4′,4′′,4′′′-CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>22</b>), <i>trans</i>-[Ru{4,4′,4′′,4′′′-CCC₆H₄CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>23</b>), and <i>trans</i>-[Ru{4,4′,4′′,4′′′,4′′′′-CCC₆H₄CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>24</b>) are reported, together with those of precursor alkynes, complexes with the donor−π-bridge−acceptor formulation that affords efficient quadratic and cubic NLO compounds; the identity of <b>19</b> was confirmed by a structural study. …”

S3 Data - by Dwight D. Harris (14484648)

“…Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). …”

S2 Data - by Dwight D. Harris (14484648)

“…Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). …”

S1 Data - by Dwight D. Harris (14484648)

“…Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). …”

S4 Data - by Dwight D. Harris (14484648)

“…Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). …”

Filamentation induced by DTPA is associated with a decrease in Nrg1 protein level, and requires the cAMP-PKA pathway and the kinase Sok1. by Elizabeth J. Polvi (3163500)

DataSheet1_Calmodulin mutations affecting Gly114 impair binding to the NaV1.5 IQ-domain.docx by Malene Brohus (840080)

“…We therefore hypothesized that the G114R variant specifically would interfere with Na_V1.5 binding. …”

Table_1_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.docx by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”

Image_3_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.tif by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”

Image_1_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.tif by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”

Image_2_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.tif by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”

A647D mutation decreases I_Na of WT and P1332L when co-expressed. by Jie Liu (15128)

Supplementary Material for: Clinical Implications of Decreased Computed Tomography Value after Ramucirumab in Advanced Gastric Cancer by Izawa N. (6834062)

“…<b><i>Objectives:</i></b> This study aimed to evaluate whether a decrease of computed tomography (CT) value for tumors serves as a predictive marker in patients with advanced gastric cancer (aGC) who have undergone chemotherapy with vascular epithelial growth factor receptor 2 inhibitor (ramucirumab). …”

Supplementary Material for: Enhanced Recovery after Surgery for Radical Cystectomy Decreases Postoperative Complications at Different Times by Lannes F. (11465377)

“…<b><i>Methods:</i></b> We performed a retrospective monocentric study using prospectively maintained databases including all patients treated by radical cystectomy between January 2015 and July 2019. …”

Data_Sheet_1_Risk of psychological distress by decrease in economic activity, gender, and age due to COVID-19: A multinational study.PDF by Minji Kim (1722313)

“…Moreover, countries with lower HDI showed a higher prevalence of decrease in economic activity, especially at lower education levels.…”

Image_2_EEG 40 Hz Coherence Decreases in REM Sleep and Ketamine Model of Psychosis.TIF by Santiago Castro-Zaballa (6238823)

“…On the contrary, gamma power was relatively high under ketamine, and similar to QW and REM sleep. We conclude that functional interactions between cortical areas in the gamma frequency band decrease in both experimental models of psychosis. …”

Image_1_EEG 40 Hz Coherence Decreases in REM Sleep and Ketamine Model of Psychosis.TIF by Santiago Castro-Zaballa (6238823)

“…On the contrary, gamma power was relatively high under ketamine, and similar to QW and REM sleep. We conclude that functional interactions between cortical areas in the gamma frequency band decrease in both experimental models of psychosis. …”