Dual Inhibition of Topoisomerase II and Tyrosine Kinases by the Novel Bis-Fluoroquinolone Chalcone-Like Derivative HMNE3 in Human Pancreatic Cancer Cells by Yong-Chao Ma (174419)

“…The viabilities of 6 different cancer cell lines treated with a range of HMNE3 doses were detected using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. …”

Fluoxetine inhibits the differentiation of hypothalamic neuroprogenitor cells. by Lígia Sousa-Ferreira (221509)

“…Representative confocal photomicrographs for mature neurons marker Neu-N (green) (<b>A</b>). Fluoxetine decreases the percentage of Neu-N positive cells and the incubation with Trk receptors inhibitor K252a (24 h) partially reverses this effect (<b>B</b>). …”

Influence of HF diet on hepatic Dnmt gene expression and global DNA methylation. by Christoph Dahlhoff (385589)

“…<p>(<b>A–C</b>) Quantification of Dnmt gene expression after 12 weeks of feeding (n = 5–6). …”

Generation of multilayered electrospun vascular scaffolds. by D. Radakovic (4509652)

“…The inset in depicts the mean fluorescence intensity ± standard deviation (SD) in a higher magnification of the indicated region (n = 3).…”

Total leukocyte counts peritoneal lavage fluid (PLF). by Mariana Cardillo Theobaldo (459623)

“…CXCL-1 expression in the groups that receive treatment reduces in relation to CLP group, interesting that the CLP+H group was higher than CLP+S (e). Data shown represent mean ± SEM. * p<0.05 indicates a significant difference with CLP control; # p<0.05 indicates a significant difference with CLP-S.…”

Table_1_Ten-Eleven Translocation (TET) Enzymes Modulate the Activation of Dendritic Cells in Allergic Rhinitis.DOCX by Hang Li (123039)

“…</p><p>Methods: The levels of TETs in peripheral blood mononuclear cells (PBMCs), peripheral myeloid DCs (mDCs), and plasmacytoid DCs (pDCs) from house dust mite (HDM)-sensitive AR patients and healthy volunteers (HC) were evaluated by qPCR and flow cytometry. The levels of 5-hydroxymethylcytosine (5hmC) and 5-methylcytosine (5mC) in PBMCs were determined by DNA-5hmC and DNA-5mC ELISA. …”

The effect of salts, pH and additives in the lysis buffer on the solubility of RGP1. by Ditte Hededam Welner (4099906)

“…Buffers 13 and 19–21, containing 1-2M salt, as well as the low-pH (4.3–5.5) buffers 11,12,15, 22 and 30 decrease the amount of soluble RGP1, while lower salt concentrations as well as several additives increase the amount of soluble RGP1 relative to the standard lysis buffer (std: 50 mM HEPES pH 8.0, 250 mM NaCl, 5 mM MgCl₂). …”

Grid division diagram. by Ming Zhang (9736)

“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”

Model calculation diagram. by Ming Zhang (9736)

“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”

Grid independence verification. by Ming Zhang (9736)

“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”

Spanish real-world experience with fingolimod in relapsing-remitting multiple sclerosis patients: MS NEXT study by Francisco Barrero (8662047)

“…Overall, the ARR significantly decreased to 0.28, 0.22 and 0.17 (74.1%, 79.7% and 83.5% of relative reduction, respectively) after 12, 24 and 36 months of treatment, <i>P</i><0.001. …”

Administration of rIL-22 reduces AHR and airway inflammation. by Christian Taube (35629)

“…<i>Panels D and E:</i> Levels of IL-13 (panel D) and CCL17 (panel E) were measured in BAL fluid by ELISA 48 h after the last challenge. Means±SEM of challenged only mice (chall, <i>n</i> = 5), non-treated sensitized and challenged mice (sens/chall, n = 12), and sensitized and challenged mice treated with 0.1 µg (0.1 µg IL-22, n = 12), 1 µg (1 µg IL-22, n = 12) and 10 µg (10 µg IL-22, n = 12) of rIl-22, respectively. …”

Effectiveness of nutritional intervention in overweight women in Primary Health Care by Nathália Luíza Ferreira (12821193)

Place avoidance parameters in SC and GST-PRW rats. by Jeffrey M. Sequeira (2580553)

Preparation of glycosylated hydrolysate by liquid fermentation with Cordyceps militaris and characterization of its functional properties by Shuang YANG (8618355)

Preparation of glycosylated hydrolysate by liquid fermentation with Cordyceps militaris and characterization of its functional properties by Shuang YANG (8618355)

Table_2_Association of Metabolic Syndrome With Prevalence of Obstructive Sleep Apnea and Remission After Sleeve Gastrectomy.XLSX by Yufei Chen (206648)

“…Then we performed a retrospective study, which was registered at ClinicalTrials.gov (ref. …”

Secondary screening and ‘hit’ validation. by Ilona Tkachyova (343715)

“…Treatment with 1.2 μM of SAHA resulted in a ~ 40% decrease in NDST enzyme activity. Experiments were conducted in triplicates. …”

Table_1_Association of Metabolic Syndrome With Prevalence of Obstructive Sleep Apnea and Remission After Sleeve Gastrectomy.XLSX by Yufei Chen (206648)

“…Then we performed a retrospective study, which was registered at ClinicalTrials.gov (ref. …”

Computational Investigation of the Lewis Acidity in Three-Dimensional and Corresponding Two-Dimensional Zeolites: UTL vs IPC-1P by Ho Viet Thang (1755028)

“…The adsorption and catalytic properties of three-dimensional zeolite UTL were investigated computationally along with properties of its two-dimensional analogue IPC-1P that can be obtained from UTL by a removal of D4R units. Adsorption properties and Lewis acidity of extra-framework Li⁺ sites were investigated for both two- and three-dimensional forms of UTL using the carbon monoxide as a probe molecule. …”