GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, “GENEREPOL study”: Lack of common variants with large effect sizes by Joe-Elie Salem (4351000)

“…QTc and TpTe increased by 5.5±3.5% and 15±19.6%, respectively, and TAmp decreased by 13.2±15.5%. …”

Supplementary Material for: Design and Baseline Characteristics of the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease Trial by Bakris G.L. (4681903)

“…The study has at least 90% power to detect a 20% reduction in the risk of primary outcome (overall two-sided significance level α = 0.05), the composite of time to first occurrence of kidney failure, a sustained decrease of eGFR ≥40% from baseline over at least 4 weeks, or renal death. …”

Characterization of <i>Pfycf93</i> gene product in <i>Plasmodium falciparum</i>. by Christopher D. Goodman (217718)

“…D) <i>Pf</i>Ycf93 protein partitions into the pellet during Triton X-114 partitioning, and a second band of 35 kDa is apparent. E) Western blotting of the 17.5 kDa band across the 48 hour asexual red blood cell cycle of synchronized parasites demonstrates that <i>Pf</i>ycf93 is not detectable at 0, 4, or 12 hours but begins to be detectable at 16 hours and then increases in abundance from 20 to 40 hours and then decreases again at 44 and 48 hours. …”

QUALIS: The journal ranking system undermining the impact of Brazilian science by RODOLFO JAFFÉ (10364631)

In vivo induction of hepatocellular carcinoma by diethylnitrosoamine and pharmacological intervention in Balb C mice using Bergenia ciliata extracts by K. K. Dar (6274934)

“…The intraperitoneal administration of B. ciliata as a protective agent, produced significant increase in albumin levels with significant decrease in the levels of tumor markers aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alpha feto protein (AFP), gamma glutamyl transferase (Y-GT), 5 nucleotidase (5NT), glucose-6-phosphate dehydrogenase (G6PDH) and bilirubin. …”

In vivo induction of hepatocellular carcinoma by diethylnitrosoamine and pharmacological intervention in Balb C mice using Bergenia ciliata extracts by K. K. Dar (6274934)

“…The intraperitoneal administration of B. ciliata as a protective agent, produced significant increase in albumin levels with significant decrease in the levels of tumor markers aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alpha feto protein (AFP), gamma glutamyl transferase (Y-GT), 5 nucleotidase (5NT), glucose-6-phosphate dehydrogenase (G6PDH) and bilirubin. …”

Ictogenic changes in input correlation and adaptation gains are associated with increased dynamical variability during baseline activity. by Scott Rich (9873638)

“…Normalization is relative to the value of these parameters in the “default” model (bright green, <i>U</i>_<i>e</i> Variance; bright red, <i>U</i>_<i>i</i> Variance and SLE rate). Plots are mean one SD over 25 independent 200 s simulations with <i>c</i> = .5. …”

Figure S1 from PARP Inhibition Induces Synthetic Lethality and Adaptive Immunity in LKB1-Mutant Lung Cancer by Li-Li Long (14963775)

“…Scale bar: 100 µm. n = 5 fields from independent tumors. Error bars represent mean ± SD. …”

Table_1_Estimation of Cerebral Hemodynamics and Oxygenation During Various Intensities of Rowing Exercise: An NIRS Study.docx by Mikio Hiura (12176669)

“…We also aimed to examine the effects of peak pulmonary oxygen consumption (V.O_2peak) on cerebral oxygenation.</p>Methods<p>Eleven rowers, consisting out of six athletes and five recreational rowers [two female; age, 27 ± 9 years; height, 171 ± 7 cm, body mass, 67 ± 9 kg; V.O_2peak, 53.5 ± 6.5 mL min^–1 kg^–1] rowed a 13-min session separated by 10 and 3 min, at 70 (Ex_70%) and 80% of V.O_2peak (Ex_80%), respectively, on a rowing ergometer, followed by three sessions of 1-min supramaximal exercise (ExSp). …”

Inhibition of lung vascular permeability in mice treated with fCB-CD34⁺ cells. by Xiaojia Huang (298132)

“…<p>(<b>A</b>) FACS analysis demonstrating greater than 95% purity of CD34⁺ cells. …”

ZnT1, MT and ZnT4 are all involved in the activation process of TNAP. by Shigeyuki Fujimoto (473814)

“…<p>(<b>A</b>) TNAP activity decreased in DT40 cells deficient in genes coding for c<i>ZnT1</i>, c<i>MT</i> and/or c<i>ZnT4</i> (<i>upper panel</i>). …”

DAF-16 contributes to inhibition of <i>mec-4d</i>–dependent AVM degeneration associated with reduced IIS signaling. by Andrea Calixto (16070)

“…Scale bar, 5 µm. (F–G) <i>mec-4d</i> worms were treated from the time of hatching with the ROS scavenger trolox (100 µm) and ascorbic acid (AA, 50 mM); after 72 hours both somas (F) and axons (G) were protected several fold compared to control nematodes (mean value for each category is shown; error bars [<1%] not included; N = 3 of 30 worms each per group; *p<0.005 by Student's t test compared with control for the SoW and AxW category).…”

Blocked NF-κB activation inhibits cytokine-upregulated IgSF molecules expression, and MSC modulates cytokine-induced NF-κB nuclear translocation. by Li Wen (169316)

“…<p>A to C shows FCM analysis of HCE-T cells treated with BMS-345541 (5 µM), a NF-κB pathway inhibitor, significantly inhibited IFN-γ (100 U/ml) and TNF (100 U/ml) induced ICAM-1 (A), HLA-ABC (B), and HLA-DR (C) expression. …”

Applied anatomy of round window and adjacent structures of tympanum related to cochlear implantation by Shraddha Jain (12814967)

“…Maximum height of the round window in our study ranged from 0.51-1.27 mm (mean of 0.69 ± 0.25 mm). Maximum width of round window ranged from 0.51 to 2.04 mm (mean of 1.16 ± 0.47 mm). …”

Impact of Transcatheter Aortic Valve Implantation on Kidney Function by Rita Calça (7888694)

“…<div><p>Abstract Background: Chronic kidney disease (CKD) is frequently present in patients with aortic valve disease. Decreased kidney perfusion as a consequence of reduced cardiac output may contribute to renal dysfunction in this setting. …”

Impact of Transcatheter Aortic Valve Implantation on Kidney Function by Rita Calça (7888694)

“…<div><p>Abstract Background: Chronic kidney disease (CKD) is frequently present in patients with aortic valve disease. Decreased kidney perfusion as a consequence of reduced cardiac output may contribute to renal dysfunction in this setting. …”

TIME SERIES TRENDS OF STREAMFLOW AND RAINFALL IN THE SANTO ANTÔNIO RIVER BASIN, BRAZIL by Fernanda L. V. Ferreira (10383961)

Pairwise variant allele frequency (VAF) histograms for virtual primary tumors. by Ruping Sun (10319284)

“…Variants were classified as public (gray), shared (green, subclonal variants shared in the two regions in comparison), or region specific (blue) on the basis of their presence in the virtual multi-region sequencing (5 regions in total) [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008838#pcbi.1008838.ref018" target="_blank">18</a>]. …”

Ni-Assisted Transformation of Graphene Flakes to Fullerenes by Irina V. Lebedeva (347621)

“…The Ni clusters are shown to reduce the activation energy for the graphene–fullerene transformation from 4.0 eV to 1.5–1.9 eV, providing the decrease of the minimal temperature at which such a transformation can be observed experimentally from about 1400 K for free graphene flakes to about 700–800 K. …”

Ni-Assisted Transformation of Graphene Flakes to Fullerenes by Irina V. Lebedeva (347621)

“…The Ni clusters are shown to reduce the activation energy for the graphene–fullerene transformation from 4.0 eV to 1.5–1.9 eV, providing the decrease of the minimal temperature at which such a transformation can be observed experimentally from about 1400 K for free graphene flakes to about 700–800 K. …”