Image1_Silibinin Therapy Improves Cholangiocarcinoma Outcomes by Regulating ERK/Mitochondrial Pathway.TIF by Yang Bai (198601)

“…</p><p>Results: Inhibition of the ERK protein by silibinin led to a significant decrease in mitochondrial membrane potential, which, in turn, caused Cytochrome C to be released from the mitochondria. …”

Radiolabeling of MSP1₁₉, the final processed fragment of MSP1, showing that it remains attached to the parasite after merozoite invasion of erythrocytes, and that it per... by Anton R. Dluzewski (53352)

“…<p><i>P. falciparum</i> schizonts were radiolabeled with ³⁵S Met/Cys at 45 hours post-invasion for 1.5 hour and a proportion of these parasites were harvested (S, schizonts). …”

Long-term psychological outcome after discharge from intensive care by Sara Pereira (778345)

“…No differences were found between the six-month and five-year follow-ups regarding EQ-5-D and EQ VAS. …”

S4 Table - by Rachita Saha (16985854)

“…<div><p>Globally, traditional knowledge systems are a powerhouse of information which can revolutionise the world, if decoded accurately and logically. …”

Accidental pharmacological poisonings in young children: population-based study in three settings by Jane C. Bell (4767096)

“…Rates (per 10,000 children) of PIC calls declined from 220 to 178; ED presentations were stable (∼22–24), with a decrease in emergency cases offset by an increase in semi- or non-urgent presentations; hospital admissions declined (8–5). …”

Table_1_Cardiomyocyte Protection by Hibernating Brown Bear Serum: Toward the Identification of New Protective Molecules Against Myocardial Infarction.pdf by Lucas Givre (11143575)

“…This cardioprotective effect was lost at 0.1%, became toxic above 5%, and was specific to the bear. Our results showed that bear serum exerts a therapeutic effect with an efficacy threshold, an optimal dose, and a toxic effect on cardiomyocyte viability after hypoxia–reoxygenation. …”

Supplementary file 1_Global burden and trends of adverse effects of medical treatment, 1990–2021: an analysis from the global burden of disease study 2021.docx by Keqing Zhang (326894)

“…Both age-standardized mortality (ASMR) and DALYs rates (ASDR) showed a gradual decline during the study period, but they still carried a heavy burden in the low SDI regions (2021 ASDR: 3.71 [95% UI: 2.90 to 5.68] per 100,000 persons-year; 2021 ASR for DALYs: 150.37 [95% UI: 109.08 to 215.24] per 100,000 persons-year). …”

Atlas of tissue- and developmental stage specific gene expression for the bovine insulin-like growth factor (IGF) system by Mani Ghanipoor-Samami (103349)

“…The stronger decrease in expression of lncRNAs (average ―16-fold) and ligands (average ―12.1-fold) compared to receptors (average ―5.7-fold) and binding proteins (average ―4.3-fold) is consistent with known functions of IGF peptides and supports important roles of lncRNAs in prenatal development. …”

Antibodies used for western blot. by Chenyi Xia (11283023)

“…Our results showed elevated H₂O₂ levels and monoamine oxidase (MAO) activity, and conversely, a decrease in the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in the hippocampus of AD rats. …”

Data_Sheet_1_Alterations of GABAergic Neuron-Associated Extracellular Matrix and Synaptic Responses in Gad1-Heterozygous Mice Subjected to Prenatal Stress.docx by Tianying Wang (695344)

“…To elucidate pathophysiological changes in ECM induced by the gene–environment interaction, we examined heterozygous GAD67-GFP (Knock-In KI; GAD67^+/GFP) mice subjected to PS from embryonic day 15.0 to 17.5. Consistent with our previous study, we confirmed a decrease in the density of PV neurons in the mPFC of postnatal GAD67^+/GFP mice with PS, which was concurrent with a decrease in density of PV neurons surrounded by perineuronal nets (PNNs), a specialized ECM important for the maturation, synaptic stabilization and plasticity of PV neurons. …”

Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification by Eva Gravesen (4740069)

“…Uremia and alfacalcidol resulted in an increase in aortic expression of genes related to fibrosis, osteogenic transformation and extracellular matrix calcification, and the BMP7 treatment resulted in a decrease in the expression of profibrotic genes. …”

KCASP1Tg and KIL-18Tg(+) mice showed emaciation and altered lipid metabolism in addition to dermatitis. by Keiichi Yamanaka (110955)

“…<p><b>A</b>) KCASP1Tg mice had erosive dermatitis at week 8, which spread across the entire face and trunk when mice were 5-months old. …”

Parathyroid Hormone Induces Bone Cell Motility and Loss of Mature Osteocyte Phenotype through L-Calcium Channel Dependent and Independent Mechanisms by Matthew Prideaux (323913)

“…PTH treatment resulted in an increase in some osteoblast and early osteocyte markers and a decrease in mature osteocyte marker expression. …”

Data_Sheet_1_The Association of CSF sTREM2 With Cognitive Decline and Its Dynamic Change in Parkinson's Disease: Analysis of the PPMI Cohort.docx by Qixiong Qin (12882533)

“…However, higher baseline CSF sTREM2 predicted greater global cognitive decline in patients with PD (β = −0.585, p = 0.039). Moreover, after a mean follow-up of 5.51 ± 1.31 years, baseline CSF sTREM2 that elevated in the middle tertile (HR = 2.426, 95% CI: 1.023–5.754, p = 0.044) and highest tertile (HR = 2.833, 95% CI: 1.226–6.547, p = 0.015) were associated with a future high risk of cognitive decline. …”

Supplementary Material for: Comparison of Postoperative Neurocognitive Function in Older Adult Patients with and without Diabetes Mellitus by vanZuylen M.L. (12761705)

“…Repeated measures ANOVA showed that mean DM patient TICS-M scores decreased 30 days postoperative (<i>F</i>(2, 200) = 4.0, <i>p</i> = 0.02), with subsequent recovery 6-month postoperative, compared to stable TICS-M scores in non-DM patients. …”

Effects on gastric mucosa induced by dental bleaching – an experimental study with 6% hydrogen peroxide in rats by Anabela Baptista PAULA (12833308)

“…There was a decrease in body weight in animals of groups handled during the study period, which was most pronounced in IV and VA groups. …”

Heat release rate (HRR) of the composites. by Rizwan Ahmed Malik (20846202)

“…The results of cone calorimetry highlighted a decrease of 11.73% in the peak values of heat release rate (HRR) which is a sign of enhancement in fire retardancy. …”

Role of <i>B. burgdorferi</i> GAG- and Fn-binding protein BBK32 in spirochete-microvascular interactions <i>in vivo</i>. by M. Ursula Norman (70618)

“…Proteinase K treatment resulted in a dramatic decrease in the level of P66 in both the infectious and non-infectious strains used here. …”

Total heat released (THR) by the composites. by Rizwan Ahmed Malik (20846202)

“…The results of cone calorimetry highlighted a decrease of 11.73% in the peak values of heat release rate (HRR) which is a sign of enhancement in fire retardancy. …”

Ileitis-induced dysbiosis is associated with increased bacteria and clonal proliferation of adherent invasive <i>E. coli</i> (AIEC). by Melanie Craven (148451)

“…Mild pathology (T4, G14) induces a decrease. (b) Moderate to severe ileitis (T8, HDI) induces <i>E. coli</i> proliferation (<i>E. coli uidA</i> quantification by real-time PCR). …”