Showing 1,141 - 1,160 results of 101,123 for search '(( 5 ((nn decrease) OR (a decrease)) ) OR ( 5 ((w decrease) OR (we decrease)) ))', query time: 1.62s Refine Results
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    SIRT5 is a proviral factor. by Marius Walter (13775591)

    Published 2022
    “…<b>E</b>. Decrease in cell-associated viral mRNA levels in A549-ACE2 cells infected with SARS-Cov-2 for 3 days at MOI = 0.1, and treated with SIRT5 and SIRT1 inhibitors Sirt5-i and Ex-527, as shown by RT-qPCR. …”
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    TUDCA decreases MPO with improved mitochondrial biogenesis, mitochondria-ER contact, and alveolar formation of HOX neonatal rat lungs. by Kirkwood A. Pritchard Jr. (13449794)

    Published 2022
    “…The increased RAC (7.3±0.8 <i>vs</i>. 4.6±0.6) and secondary septation (34.5±3.0 <i>vs</i>. 24.8±1.1) with decreased MLI (65.1±2.9 μm <i>vs</i>. 82.3±8.4 μm) and increased capillary area (12.9±1.2% <i>vs</i>. 10.5±0.9%) demonstrate a protective effect of TUDCA to the HOX neonatal lungs (n = 6, p<0.05, 3 for each sex). *: p<0.05.…”
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    Image_5_GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.png by Jan Nagenborg (14771194)

    Published 2023
    “…</p>Methods and results<p>Here, we demonstrate reciprocal expression regulation of STAT5A and STAT5B in human atherosclerotic lesions. …”
  15. 1155

    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

    Published 2021
    “…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

    Published 2021
    “…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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    The 5’-nucleotidase S5nA is dispensable for evasion of phagocytosis and biofilm formation in <i>Streptococcus pyogenes</i> by Marcel-Lino Dangel (6281693)

    Published 2019
    “…Here we show that deletion of the S5nA gene does not significantly affect growth in human blood, evasion of phagocytosis by neutrophils, formation of biofilms and virulence in an infection model with larvae of the greater wax moth <i>Galleria mellonella</i> in <i>S</i>. …”