QC, including cluster size thresholding and declumping, improves precision, sometimes at the expense of recall, for images with lower SNR values. by Jenny M. Vo-Phamhi (11250803)

“…<b>(C)</b> Thresholding clusters by the number of annotations in the cluster and by the fraction of unique workers who contribute multiple times to the cluster improved recall by 17%, while decreasing precision by 11% on average, in an experiment with nine images with 50, 100, and 150 spots; mean SNR = 5, 10, and 15; and average nearest neighbor distance (NND) ≈ 11.5, 15, and 20.5.…”

BIG1 is required for the survival of deep layer neurons, neuronal polarity, and the formation of axonal tracts between the thalamus and neocortex in developing brain by Jia-Jie Teoh (3929852)

“…<i>In vitro</i>, BIG1-deficient neurons showed a delay in neuronal polarization. BIG1-deficient neurons were also hypersensitive to low dose glutamate (5 μM), and died via apoptosis. …”

Lowering oxygen exposure reduces oxidative stress, DNA damage and genomic instability in thymus. by Ho Joong Sung (221317)

“…Data shown as mean ± SEM, with n = 5. <b>C.</b> Representative images of decreased oxidative DNA damage detected by avidin-FITC (Av-FITC) staining for 8-oxoG in thymus tissue from <i>p53−/−</i> mouse exposed to 10% versus 21% oxygen for 2 to 4 wk. …”

IPF fibroblasts are desensitized to collagen rich matrix induced cell death in the presence of 3MA or CQ. by Richard Seonghun Nho (54078)

“…All assays were performed in three separate experiments to measure fibroblast viability or their proliferation using IPF cells in lane 5 and control fibroblasts in lane 3 in an upper panel in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0094616#pone-0094616-g001" target="_blank">Fig 1A</a>.…”

Table_1_Mesenchymal Stromal Cell-Derived Extracellular Vesicles Attenuate Dendritic Cell Maturation and Function.xlsx by Monica Reis (5947445)

“…MiR-21-5p mimic transfected DCs showed a clear trend of reduced CCR7 expression and a significantly decreased migratory ability toward the CCL21. …”

Data_Sheet_1_Mesenchymal Stromal Cell-Derived Extracellular Vesicles Attenuate Dendritic Cell Maturation and Function.docx by Monica Reis (5947445)

“…MiR-21-5p mimic transfected DCs showed a clear trend of reduced CCR7 expression and a significantly decreased migratory ability toward the CCL21. …”

Expression of ectopic APE1^WT protein confers cells protection to genotoxic damage but not to FAs-induced cytotoxicity. by Laura Cesaratto (446418)

“…After exposure to 2.5 mM H₂O₂ no significant decrease in cell viability was detected for APE1^WT clone compared to empty and APE1^NΔ33 cell clones. …”

Related to Fig 4. <i>NDUFS7</i> depletion in neurons lowers the failure rate of neurotransmission at very low calcium concentrations. by Bhagaban Mallik (12459375)

“…The number of failures was counted per hundred trials in each genotype. There is a marked decrease in failure rate in motor neurons driving <i>UAS-NDUFS7[RNAi]</i>. …”

SCI alters the mRNA expression of canonical Wnt signalling components. by Carmen María Fernández-Martos (5649061)

“…SCI did not alter the transcription of the <i>LRP5/6</i> co-receptors, although there was a striking increase in <i>GSK3-β</i> expression that coincided with that of the <i>Dkk</i> inhibitors, as well as a mild up-regulation of <i>β-catenin</i> after 6 hours that gradually decreased until the end of the study. …”

Shannon Diversity Scores. by Brittany E. Goldberg (765746)

“…All tooth samples from patient 12 were from primary teeth, and her average shannon score was decreased relative to the other patients with a value of 5.0. …”

Stimuli and design. by Christopher R. Kelly (36894)

“…The centers of mass for the three clusters, on (V/F/N) coordinates, are: violent clips [44.4, 28.0, 28.8]; fearful clips [13.5, 43.4, 25.1]; neutral clips [2.5, 3.3, 25.1]. …”

DataSheet1_Long-Term Variation in Wintertime Atmospheric Diffusion Conditions Over the Sichuan Basin.docx by Guoyin Wang (10939987)

“…Both V_E and ASI reveal a decrease tendency of atmospheric diffusion condition from the northwestern portion of the basin to the southeast. …”

Mathematical Modeling Reveals Kinetics of Lymphocyte Recirculation in the Whole Organism by Vitaly V. Ganusov (142019)

“…The model also predicts a relatively short average residence time of TDLs in the spleen (2.5 hours) and a longer average residence time of TDLs in major lymph nodes and Peyer's patches (10 hours). …”

Adhesion test with Caco2 cells on senescent HPMC monolayer. by Danilo Ranieri (297480)

“…<p>A) HPMCs from the #062 peritoneal wash were cultured at P2 and P4 as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057659#pone-0057659-g005" target="_blank">figure 5</a>. …”

Electrical hearing thresholds. by Verena Scheper (538613)

“…<p>EABR thresholds in AP+ES treated animals (A) increased in 3 and decreased in 3 individuals. …”

Distinct CLP migratory groups persist under low serum conditions. by Joël Beyeler (652358)

“…<p>The graphs show the RWC in scratch wound assays at 24 h in 0.3% FCS/DMEM (*p<0.05, **p<0.01, ***p<0.001). (A) Despite a general decrease of the RWC, “fast” and “intermediate” CLP groups could still be distinguished under low-serum conditions. …”

Data_Sheet_1_Little Impact of NaCl Reduction in Swiss-Type Cheese.docx by Valérie Gagnaire (783586)

“…Casein hydrolysis in vitro was similar or higher at pH 5.2, i.e., cheese pH, compared to pH 7.5, and slightly decreased at the highest salt concentrations (3.0 and 4.4%). …”

Table 1_Trends in the disease burden of maternal sepsis and other maternal infections attributable to iron deficiency from 1990 to 2021 and its projection until 2050.docx by Chunfeng Zhu (327990)

“…The ASMR and age-standardized DALY rate of MSMIs attributable to iron deficiency were negatively correlated with SDI. Projections indicated a continued decrease in the burden of MSMIs attributable to iron deficiency by 2050.…”

Do psychosocial factors modify the negative association between disability and life satisfaction in old age? by Thomas Puvill (726017)

“…The impact of (I)ADL disabilities on life satisfaction was strongest at age 50 and gradually decreased with increasing age (p trend < 0.001). Mental health explained more variance; 5.75% for depressive symptoms and 2.50% for loneliness and for social resources this ranged from 0.09% to 0.47% (all p < 0.001). …”

Fatigue indices and perceived exertion highlight ergometer specificity for repeated sprint ability testing by Hugo Kerhervé (618369)

“…During recovery, RPE was consistently higher on NMT at 1, 3 and 5 min postexercise compared to CE. These findings indicate that RSA performed on NMT induces greater fatigue and physiological load than CE, which originated in the lower resistive torque typically used on NMT compared to CE, resulting in a frontloaded power output profile from the greater acceleration and cadence. …”