Data_Sheet_1_Chronic Δ9-tetrahydrocannabinol impact on plasticity, and differential activation requirement for CB1-dependent long-term depression in ventral tegmental area GABA neu... by Isaac Ostlund (14349531)

“…In young mice, VTA GABA cells exhibit a form of synaptic plasticity known as long-term depression (LTD) that is dependent on cannabinoid 1 (CB1) receptors preceded by metabotropic glutamate receptor 5 (mGluR5) signaling to induce endocannabinoid production. …”

Image_1_Identification of Immune-Related Gene Signature and Prediction of CeRNA Network in Active Ulcerative Colitis.tif by Mengmeng Xu (1696420)

“…RT-PCR revealed that andrographolide (AGP) significantly inhibited the expression of hub genes. Finally, we identified XIST and three miRNAs (miR-9-5p, miR-129-5p, and miR-340-5p) as therapeutic targets.…”

Data_Sheet_1_Identification of Biologically Active Ganoderma lucidum Compounds and Synthesis of Improved Derivatives That Confer Anti-cancer Activities in vitro.docx by Michelle M. Martínez-Montemayor (383853)

“…Three of the seven compounds (ergosterol, 5,6-dehydroergosterol and ergosterol peroxide) exhibited significant in vitro anti-cancer activities, while we report for the first time the structure elucidation of 5,6-dehydroergosterol from Ganoderma lucidum. …”

Overlap of epigenetic signatures and Hi-C contacts. by Ittai E. Eres (7010684)

“…<p>(A) Hi-C loci that do not make contact with promoters are ranked in order of decreasing DC FDR (x-axis). …”

Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis by Lorena Fernandez-Mosquera (5077820)

“…</p> <p><b>Abbreviation</b>: ΔΨ_m: mitochondrial transmembrane potential; AMP: adenosine monophosphate; AMPK: AMP-activated protein kinase; ATG5: autophagy related 5; ATP: adenosine triphosphate; ATP6V0A1: ATPase, H+ transporting, lysosomal, V0 subbunit A1; ATP6V1A: ATPase, H+ transporting, lysosomal, V0 subbunit A; BSA: bovine serum albumin; CCCP: carbonyl cyanide-m-chlorophenylhydrazone; CREB1: cAMP response element binding protein 1; CTSD: cathepsin D; CTSF: cathepsin F; DMEM: Dulbecco’s modified Eagle’s medium; DMSO: dimethyl sulfoxide; EBSS: Earl’s balanced salt solution; ER: endoplasmic reticulum; FBS: fetal bovine serum; FCCP: carbonyl cyanide-p-trifluoromethoxyphenolhydrazone; GFP: green fluorescent protein; GPN: glycyl-L-phenylalanine 2-naphthylamide; LAMP1: lysosomal associated membrane protein 1; MAP1LC3B/LC3B: microtubule associated protein 1 light chain 3 beta; MCOLN1/TRPML1: mucolipin 1; MEF: mouse embryonic fibroblast; MITF: melanocyte inducing transcription factor; ML1N*2-GFP: probe used to detect PtdIns(3,5)P₂ based on the transmembrane domain of MCOLN1; MTORC1: mechanistic target of rapamycin kinase complex 1; NDUFS4: NADH:ubiquinone oxidoreductase subunit S4; OCR: oxygen consumption rate; PBS: phosphate-buffered saline; pcDNA: plasmid cytomegalovirus promoter DNA; PCR: polymerase chain reaction; PtdIns3P: phosphatidylinositol-3-phosphate; PtdIns(3,5)P₂: phosphatidylinositol-3,5-bisphosphate; PIKFYVE: phosphoinositide kinase, FYVE-type zinc finger containing; P/S: penicillin-streptomycin; PVDF: polyvinylidene fluoride; qPCR: quantitative real time polymerase chain reaction; RFP: red fluorescent protein; RNA: ribonucleic acid; SDS-PAGE: sodium dodecyl sulfate polyacrylamide gel electrophoresis; shRNA: short hairpin RNA; siRNA: small interfering RNA; TFEB: transcription factor EB; TFE3: transcription factor binding to IGHM enhancer 3; TMRM: tetramethylrhodamine, methyl ester, perchlorate; ULK1: unc-51 like autophagy activating kinase 1; ULK2: unc-51 like autophagy activating kinase 2; UQCRC1: ubiquinol-cytochrome c reductase core protein 1; v-ATPase: vacuolar-type H+-translocating ATPase; WT: wild-type</p>…”

NDPK stimulates growth in liquid medium. by Sarah J. Annesley (202479)

“…<p>The generation time for wild type and NDPK transformants was measured in three independent experiments and the mean for each transformant was plotted against the NDPK expression index (defined as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0026024#pone-0026024-g005" target="_blank">Fig. 5</a>). …”

Loss of Circulating CD4 T Cells with B Cell Helper Function during Chronic HIV Infection by Kristin L. Boswell (517523)

“…In co-culture experiments we confirmed CXCR5+ cells from HIV-uninfected donors provide help to B cells and more specifically, we identified a CCR7^highCXCR5^highCCR6^highPD-1^high CD4 T cell population that secretes IL-21 and enhances isotype-switched immunoglobulin production. …”

Steady-state and dynamic FRET analysis of TRPV1-Caveolin-1 interaction. by Barbara Storti (193389)

“…(a) Donor (Caveolin-EGFP) emission image; (b) acceptor (TRPV1-RFP) emission image; (c) SE-FRET intensity image (scale bar: 5 μm); (d) zoom of a cellular region where FRET-<i>i</i>MSD analysis is later performed; (e) donor-normalized apparent FRET efficiency <i>E</i><sub><i>D</i>.…”

Image_2_Menthol Flavor in E-Cigarette Vapor Modulates Social Behavior Correlated With Central and Peripheral Changes of Immunometabolic Signalings.TIFF by Zhibin Xu (288627)

“…Multiple sera cytokines including C5, TIMP-1, and CXCL13 were decreased accordingly as per their peripheral immunometabolic responses to menthol flavor in the nicotine vapor. …”

Image_1_Menthol Flavor in E-Cigarette Vapor Modulates Social Behavior Correlated With Central and Peripheral Changes of Immunometabolic Signalings.TIFF by Zhibin Xu (288627)

“…Multiple sera cytokines including C5, TIMP-1, and CXCL13 were decreased accordingly as per their peripheral immunometabolic responses to menthol flavor in the nicotine vapor. …”

The Involvement of Oxytocin in the Subthalamic Nucleus on Relapse to Methamphetamine-Seeking Behaviour by Sarah Jane Baracz (784523)

“…We found that local administration of the highest oxytocin dose (3.6 pmol) into the STh decreased METH-induced reinstatement and desGly-NH2,d(CH2)5[D-Tyr2,Thr4]OVT had a non-specific effect on lever press activity. …”

Image_2_Menthol Flavor in E-Cigarette Vapor Modulates Social Behavior Correlated With Central and Peripheral Changes of Immunometabolic Signalings.TIFF by Zhibin Xu (288627)

“…Multiple sera cytokines including C5, TIMP-1, and CXCL13 were decreased accordingly as per their peripheral immunometabolic responses to menthol flavor in the nicotine vapor. …”

Table_1_Menthol Flavor in E-Cigarette Vapor Modulates Social Behavior Correlated With Central and Peripheral Changes of Immunometabolic Signalings.pdf by Zhibin Xu (288627)

“…Multiple sera cytokines including C5, TIMP-1, and CXCL13 were decreased accordingly as per their peripheral immunometabolic responses to menthol flavor in the nicotine vapor. …”

Table_1_Menthol Flavor in E-Cigarette Vapor Modulates Social Behavior Correlated With Central and Peripheral Changes of Immunometabolic Signalings.pdf by Zhibin Xu (288627)

“…Multiple sera cytokines including C5, TIMP-1, and CXCL13 were decreased accordingly as per their peripheral immunometabolic responses to menthol flavor in the nicotine vapor. …”

Image_1_Menthol Flavor in E-Cigarette Vapor Modulates Social Behavior Correlated With Central and Peripheral Changes of Immunometabolic Signalings.TIFF by Zhibin Xu (288627)

“…Multiple sera cytokines including C5, TIMP-1, and CXCL13 were decreased accordingly as per their peripheral immunometabolic responses to menthol flavor in the nicotine vapor. …”

Pseudo XY bodies containing synapsed axes in wild type embryonic oocytes. by Fabrizia Carofiglio (418861)

“…<p>(A–B) Triple immunostaining with anti-HORMAD1 (red), anti-TEX12 (green) and anti-γH2AX (blue) of oocyte nuclei from E17.5 wild type embryos. …”

N-AChE-S overexpression in AD cortical neurons associates with Tau hyper-phosphorylation. by Debra Toiber (53524)

“…<p>A. <u>Differential fractionation of AChE hydrolytic activity</u>. …”

Diagnostic and prognostic role of protein and ultrastructural alterations at cell–extracellular matrix junctions in neoplastic progression of human oral malignancy by Harsh Nitin Dongre (12252731)

“…TEM analysis in parallel tissues revealed a significant decrease in HD number and increase in the length of basal lamina (BL) in hyperplasia. …”

Wnt/β-catenin reduces <i>MKX</i> and <i>TNMD</i> expressions in <i>SCX</i>-programmed tendon progenitors (hMSC-Scx cells). by Yasuzumi Kishimoto (4282138)

“…Relative expressions of <i>AXIN2</i>, <i>MKX</i>, and <i>TNMD</i> in hMSC-Scx cells treated with 50 ng/ml Wnt3a with or without 5 μM IWR <b>(A)</b>, 0 to 2 μM BIO <b>(B)</b>, or 0 to 20 μM IWR <b>(C)</b> are indicated. …”

AMPKα1 silencing and compound C blocks the inhibitory effects of AICAR on TGF-β1-induced myofibroblast activation. by Kuan-Hsing Chen (166501)

“…Immunoblotting of the cell lysates, showed that the inhibitory effects of AICAR on α-SMA expression were decreased by the treatment with Compound C in a dose-dependent manner. …”