Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

Subjects:

MAP-2 decrease follows the early PSA-NCAM reduction induced by glutamate exposure. by María Fernanda Podestá (639243)

“…<p>Hippocampal neurons in culture (DIV 12–13) were briefly exposed to 5 µM glutamate and evaluated 1, 3, 6 and 12 h later. …”

MMP-2 production is decreased following ALK5 inhibition. by Rebecca A. Scott (488956)

EGFR/ERK signaling activity decreases throughout LEC elimination with endocytic activity dependency. by Kevin Yuswan (19845885)

Insulin ICV injection (14 mU) decreases olfactory detection in fasted rats. by Pascaline Aimé (293920)

“…Before the conditioning, during the last day of habituation (Hab.), both tubes were filled with pure water, and during the first day of aversion acquisition (Av.), both tubes were filled with ISO 10⁻⁵. A repeated measure ANOVA revealed a significant effect of the aversive conditioning (p<0.0001). …”

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(F)</b> qPCR analysis for cholesterogenic genes from NIH3T3 cells exposed to cholesterol (50 μm) or 25-hydroxycholesterol (10 μm) under 5% or 1% CO₂ for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, ***<i>P</i> < 0.001, nonsignificant (ns), two-way ANOVA with Bonferroni’s multiple comparisons test). …”

Nasal mucociliary clearance was decreased in <i>Ttll1</i>^−/− mice. by Toshiyuki Iwata (419270)

“…<p>(A) Tosufloxacin (50 mg/kg) was administered to <i>Ttll1</i>^−/− mice with rhinosinusitis to inhibit cough for 7 days. …”

KCl treatment increases Elk1 SUMOylation and decreases katanin-p60 expression. by Ece Selçuk (436963)

PDGF-BB-induced NR4A1 expression is decreased after treatment with the NF-κB inhibitor BAY11-7082. by Glenda Eger (636934)

A C5a-Immunoglobulin complex in chronic lymphocytic leukemia patients is associated with decreased complement activity by Regina Michelis (2889092)

“…In patients with abnormal C5, basal levels of sC5b-9 and C5a were increased while activities of the CP and of the CP C5-convertase, the immediate C5-upstream complex, were decreased compared to NC and to patients with normal C5. …”

L665W decreased AR5A binding to H77/JFH1 particles and to the E1/E2 complex in H77/JFH1 infected cells, but did not alter receptor dependency. by Rodrigo Velázquez-Moctezuma (3776023)

Flies decrease the level of aggression as the availability of food resource increases. by Rod S. Lim (622045)

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…However, how global land use changes impact soil N supply and potential N loss remains elusive. By compiling a global data set of 1,782 paired observations from 185 publications, we show that land use conversion from natural to managed ecosystems significantly reduced NNM by 7.5% (−11.5, −2.8%) and increased NN by 150% (86, 194%), indicating decreasing N availability while increasing potential N loss through denitrification and nitrate leaching. …”

Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant by Ittipat Meewan (7455041)

“…Hepatitis C virus (HCV) is a human pathogen with high morbidity. The HCV NS3/4A protease is essential for viral replication and is one of the top three drug targets. …”

CsA reduces Flk1 protein expression and significantly decreases the percentages of Flk1+ cells. by Seung-Cheol Choi (686982)

Decrease of SMAD3 protein, but not SMAD2 in DBA iPSCs. by Jingping Ge (636557)

“…The nuclear p-SMAD2 decreased in <i>RPL5</i> mutant and corrected lines. …”

CD107a-, IFNγ- and MIP 1β-producing Vγ9Vδ2 T-cell subsets decrease in HIV+ patients. by Rita Casetti (608635)

Foxo1 decreases <i>SCN5a</i> promoter activity. by Weike Mao (181121)

Nicotine decreased Wnt5a expressions in SK-BR-3 cells. by Masanori A. Murayama (5774585)

A decrease in circulating CXCR5+CD4+ Tfh cells is associated with HCC progression, and CXCR5+CD4+ Tfh cells are decreased in tumor regions. by Yiqiong Jia (692871)

“…<p>(A) The prevalence of CXCR5+CD4+ Tfh cells decreases with progressive stages in HCC. …”