Bortezomib in combination with the PLK1 inhibitor BI 2536 induces a significant downregulation of the total levels and phosphorylation of Bcr-Abl, a decrease of downstream phosphorylated STAT5 and a caspase-dependent cell death in TKIs-resistant and –sensitive K562 cell lines. by Octavian Bucur (470431)

“…K562 and K562-R cells were treated with 9nM bortezomib and 8nM BI 2536 for 60h, followed by the detection of Bcr-Abl and phosphorylated STAT5. The combined treatment resulted in a marked decrease of the total levels of Bcr-Abl, which correlates with a decrease in the phosphorylation of the downstream STAT5 protein, in both K562 and K562-R cells. β-Actin was used as an internal loading control. …”

RNF5 loss decreases ERK and Akt activation, CDK1 and Smo expression and KSHV lytic replication in PEL cells. by Xiaojuan Li (351842)

TachypleginA treatment causes a decrease in the motor activity of the TgMyoA motor complex. by Aoife T. Heaslip (207534)

Transcriptional and translational markers of syncytialization and biochemical differentiation are significantly decreased by rotenone. by O’Llenecia S. Walker (8486163)

Establishment of HIV latency correlates with elevated amounts of AcH4 and Brd4 but drastically decreased AcH3 content on viral LTR. by Zichong Li (5131241)

PB + PER exposure decreased SYP staining in the hippocampi and cerebral cortices of exposed mice. by Zuchra Zakirova (431614)

Rotenone exposure decreases GSH level in porcine oocytes. by Geun Heo (14185618)

Decrease in PP2A activity increases phosphorylation of p38MAPK, pMAPKAPK2 and Hsp27 in CD133+ cells. by Shih-Pei Lin (117914)

Omega-3 enriched oils dose-dependently decrease macrophage lipid uptake. by Agua Sobrino (368634)

Normal TLR4 and MD2 expression and decreased IL10 secretion and A20 expression by <i>cpdm</i> BMDC. by Zhe Wang (41178)

Spatial distribution of total consumer biomass response types, for the seven considered MEMs forced with GFDL-SSP5-8.5. by Vianney Guibourd de Luzinais (16871842)

Applying an obligate carrier to filtering decreased the number of variants to five, of which the intronic variant in <i>HIVEP3</i>/<i>ENSCAFG00000035604</i> had complete penetrance... by Maria Kaukonen (655106)

Fig 5 - by Evelyn Medawar (9774392)

Figure S1 - Cigarette Smoke Decreases Airway Epithelial FABP5 Expression and Promotes <em>Pseudomonas aeruginosa</em> Infection by Fabienne Gally (260470)

Fig 5 - by Zhen Jiao (135475)

S5 Fig - by Chao Yang (174810)

Potential influence of vFLIP in a short term apoptosis model. by Barbara Ruder (8379354)

Fig 5 - by Yingjie Hu (1579000)

Reduced RAB27A expression in melanocytes significantly decreases the melanin content in the epidermis, resulting in a lighter skin surface color of HSS. by Yasuko Yoshida-Amano (314746)

Barcoding Beetles: A Regional Survey of 1872 Species Reveals High Identification Success and Unusually Deep Interspecific Divergences by Mikko Pentinsaari (634506)

“…Moreover, the sequence divergences between nearest neighbor species were considerably higher than those reported for the only other insect order, Lepidoptera, which has seen intensive analysis (11.99% vs up to 5.80% mean NN divergence). Although maximum intraspecific divergence increased and average divergence between nearest neighbors decreased with increasing sampling effort, these trends rarely hampered identification by DNA barcodes due to deep sequence divergences between most species. …”