Search alternatives:
teer decrease » greater decrease (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
teer decrease » greater decrease (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality
Published 2015“…In contrast, for the <i>SLC5A11</i> locus, we found increased levels of <i>myo</i>-inositol in urine whereas mGWAS in blood reported decreased levels for the same genetic variant. …”
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Twenty-two identified and replicated loci and their overlap with associations to metabolic traits and clinical phenotypes.
Published 2015“…<p><sup>a</sup> SNP with the strongest association to targeted metabolic traits (“lead SNP”)</p><p><sup>b</sup> SNP with the strongest association to non-targeted metabolic traits</p><p><sup>c</sup> manually added to the list of most plausible candidate genes derived by evidence-based selection</p><p><sup>d</sup> additional candidates match to other non-targeted traits that also associate with the lead SNP</p><p><sup>e</sup> results from GWAS (<i>P</i> < 5.0×10<sup>−8</sup>)</p><p><sup>f</sup> mutations determined in clinical studies</p><p>For each locus, we selected all variants that displayed genome-wide significant association signals to metabolic traits in the SHIP-0 cohort. …”
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Downregulation of SPHK1 expression decreases the resistance of glioma cells to apoptosis.
Published 2013“…<p>(A) SPHK1 knockdown was achieved by introducing specific shRNAs in glioma cells. α-tubulin was used as a loading control. …”
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