Table 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.docx by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Table 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Vesicular zinc storage is modified by mutants that affect tyrosine-mediated ZnT3 oligomer formation. by Gloria Salazar (179015)

“…A) PC12 cells non transfected (NT) and cells expressing mouse ZnT3HA or myc-tag human ZnT1, 3, 4, 5 and 7 were stained with zinquin and fluorescence analyzed by flow cytometry, results are express as mean±SD in three independent experiments for human ZnTs. hZnT1: 112±26.5, hZnT3: 241±51.3, hZnT4: 169±9.7, hZnT5 227±20.3, hZnT7: 124±4.19. …”

The potential mechanism for the elevated ROS levels. by Weimin Wang (145168)

“…(D) Gene expression of NOX2 and NOX4 in the control and Ara-C groups. (E) The mean increase/decrease of mitochondrial ROS and total ROS in Ara-C cells treated with DPI or Mito-Tempo. …”

UV-C light intensity measured within the array. by Eric Schnell (302252)

“…<p>A. Schematic demonstrating array dimensions and axes. …”

Effects of chronic clenbuterol treatment on intact muscle contractile properties. by Pascal Sirvent (589813)

“…<p><b>A,</b> Effects of clenbuterol (CLB) treatment for 21 days on EDL maximal isometric tension. …”

Inhibition of cell invasion by silencing endogenous ANO1 in transwell assay. by Linghan Jia (787391)

“…Data are expressed as mean ± s.e.m.</p>…”

Significant reduction in gene and protein expression of proinflammatory cytokines in BV-2 cells treated with DAPT+LPS and LiCl+LPS, respectively. by Qiong Cao (531973)

“…<p>Bar graphs (A, B, C, D) show expression changes of IL-1β, IL-6, iNOS and TNF-α in different treatments. …”

The inhibitor of miR-21 inhibited miR-21-inducing expression of HIF-1α and VEGF, activation of AKT and ERK1/2, and angiogenesis. by Ling-Zhi Liu (20849)

“…(E) The number of blood vessels were counted from replicate experiments, and normalized to that of the control group as relative angiogenesis. The data are the mean ±SD from 6 replicate experiments. ##, indicates the significant decrease when compared to that of the control (<i>p</i><0.01).…”

Selective cytotoxicity of AQHAR in human cancer cells. by Kejuan Li (2580184)

“…<p>(A) Cell viability of human cancer and normal cells treated with indicated doses of AQHAR. …”

Effect of signaling pathway inhibitors on ox-LDL-induced Klotho downregulation in proximal tubular cells. by Cristina Sastre (503532)

“…<p>Pretreatment of MCT with parthenolide (1 µM) or PD098059 (50 µM) for 1 hour attenuates the decrease in Klotho mRNA (<b>A</b>) and protein (<b>B</b>) induced by ox-LDL (25 µg/mL). …”

rAd-p53 induced apoptosis was reverted by Fbxw7-specific siRNA. by Kangsheng Tu (428934)

“…C) The percentage of apoptotic Hep3B cells infected with rAd-p53 was decreased by Fbxw7-specific siRNA. Values are mean±standard error, n=3. * <i>P</i><0.05 <i>vs</i> control; ** <i>P</i><0.05 <i>vs</i> Fbxw7 siRNA; *** <i>P</i><0.05 <i>vs</i> rAd-p53.…”

Impaired myogenic differentiation in myotubes from SMA patients. by Nicole Hellbach (5562965)

“…<p>Representative fluorescence microscopy showing myotubes stained for MYOG, MYH1E and TNNT as well as cell nuclei (Hoechst) and quantification of the positively stained cells showing significant decrease of the later developmental markers in SMA Type 1 cells (A). …”

BV modulates GSK3β-mediated suppression of Foxp3⁺ Treg cells <i>in vitro</i>. by Ran Fu (434520)

“…<p>(A), Representative flow cytometric results of Foxp³⁺ Treg cells in cultured splenocytes after incubation with BV or transfection with GSK3β siRNA for 72 h. …”

Dramatic reduction of Dystrophin Dp71 expression in detached retina. by Abdoulaye Sene (258556)

“…<p>A: Western blot analysis of Dp71 and β-Actin total protein levels in control and detached retina 24 h and 7 days after experimental retinal detachment. …”

Analysis of rhodopsin level in LIRD mice treated with (±)-RPE65-61. by Yuhong Wang (85102)

“…(A) Expression levels of opsin in the retinas of control and LIRD mice were measured using anti-rhodopsin (1D4) antibody. …”

Differential effects of E2 on the functional coupling of C6 and F98 cells. by Zahra Moinfar (2504494)

“…<p>a) Significant decrease of coupling of C6 cells and b) Significant increase of coupling of F98 cells after E2 treatment. …”

Co-cultures of RGCs and Müller cells. by Xandra Pereiro (3924971)

“…The data represent the mean ± SEM. Scale bar = 100 μm, *p<0.05.</p>…”

Comparing inter-rater agreement for IQ dimensions in terms of motivation by assessors’ groups. by Marko Poženel (14019907)

“…The figure depicts all IQ dimensions and the mean value of the aforementioned dimensions. ICC values above the identity line (i.e. the dotted diagonal) represent an increase in ICC, while values below represent a decrease in ICC, when comparing unmotivated (Q4) and motivated (Q1) groups.…”

Developmentally regulated promoter-switch transcriptionally controls function during embryonic hematopoiesis-2 by Amir Pozner (78042)

“…Following FACS analysis an equal number (1 × 10) of E15.5 WT or P2Annexin V negative thymocytes were incubated with TPA (20 ng/ml) and ConA (5 μg/ml) for 48 h. …”