Differential sensitivity to PI3K/AKT pathway regulation is lost in isolated cancer cells. by Maria Laura Polo (364546)

“…Proliferation assay (³H-thymidine incorporation) in primary C4-HD (left) or C4-HI (right) cells incubated during the last 48 hrs with 0.01 µM MPA and 5, 10 and 20 µM PD98059 or LY294002. For the combined treatment, the inhibitor was used at a dose of 10 µM. …”

<i>In-silico</i> identification of fingerprint of pyrazolyl sulfonamide responsible for inhibition of <i>N</i>-myristoyltransferase using Monte Carlo method with index of ideality... by Ashwani Kumar (55732)

“…One QSAR model with best <math><msubsup><mrow><mi>R</mi></mrow><mrow><mi>calibration</mi></mrow><mrow><mn>2</mn></mrow></msubsup></math> = 0.8638 for split 2 was considered as the leading model. A greater value of cRp² <i>i.e.</i> 0.5 for all models in Y-randomization test showed the robustness of developed models. …”

Effect of SPARC on the modulation of ECM proteins in proliferating C2C12 cells. by Aicha Melouane (4530787)

“…Addition of SPARC induced collagen 1a1 expression, however, SPARC inhibition decreased it. …”

Single-Beat Noninvasive Imaging of Ventricular Endocardial and Epicardial Activation in Patients Undergoing CRT by Thomas Berger (72614)

“…Left ventricular propagation velocities were significantly decreased in CHF patients as compared to the control group (1.6±0.4 versus 2.1±0.5 m/sec; p<0.05). …”

Table_1_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.docx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

DataSheet_1_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.xlsx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

Estrogen Receptor inhibition prevents estradiol-17ß-d-glucuronide (E17G)-induced endocytic internalization of Abcb11 and Abcc2 in perfused rat liver. by Ismael R. Barosso (116985)

“…ICI (0.5 µM, 15 min previous to E17G) prevented the internalization of canalicular transporters, as illustrated by a control-like pattern of Abcb11 and Abcc2 distribution. …”

Clinical Cysticercosis epidemiology in Spain based on the hospital discharge database: What's new? by Zaida Herrador (635669)

“…From 1998 to 2008, an increasing trend in the number of CC hospitalizations was observed, decreasing afterwards, in parallel with a decrease in the external migration rate. …”

Table1_Left ventricular structure and function following renal sympathetic denervation in patients with HFpEF: an echocardiographic 9-year long-term follow-up.docx by Alexander Vogt (375813)

“…We found a significant reduction of the HFA-PEFF score from 5.48 ± 0.51 points at baseline to 4.33 ± 1.53 points at the 9-year follow-up (P < 0.01). …”

Image_1_Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells.tif by Nunzia Mollo (6891068)

“…These effects, together with a significant increase of basal ATP content and oxygen consumption rate, and a significant decrease of reactive oxygen species (ROS) production, provide strong evidence of an overall improvement of mitochondria bioenergetics in trisomic cells. …”

BMI and Lifetime Changes in BMI and Cancer Mortality Risk by Niloofar Taghizadeh (724983)

“…Both short-term annual increase and decrease in BMI were associated with a lower mortality risk from any cancer [all subjects: (0.67 (0.47-0.94)) and (0.73 (0.55-0.97)), respectively]. …”

Table_1_Fish kills and insecticides: historical water quality patterns in 10 agricultural watersheds in Prince Edward Island, Canada (2002–2022).PDF by Miranda Crawford (14683993)

“…The changing climate significantly adds to the complexity of monitoring these systems as the regional rate of change is exceptionally high (e.g., a 0.70°C to 1.14°C increase in air temperature and 5–8% decrease in precipitation in the last 3 decades). …”

Image_1_Protein Kinase C-Dependent Effects of Neurosteroids on Synaptic GABAA Receptor Inhibition Require the δ-Subunit.pdf by Erica L. Littlejohn (10832151)

“…Although Allo did not influence GABAergic neurotransmission during initial application (5–20 min), a TTX-insensitive prolongment of decay time and increase in frequency of GABAergic currents was established after Allo was removed from the bath for at least 30 min (LtAllo). …”

Illinois agility test [22]. by Rıdvan Ergin (22265431)

“…At the same time, it has been noted that a decrease in age increases agility performance, while an increase in age enhances jump height. …”

DataSheet_2_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.xlsx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

DataSheet_1_Herbaceous peony PlACLB2 positively regulates red petal formation by promoting anthocyanin accumulation.doc by Yuting Luan (13873364)

“…On the one hand, silencing PlACLB2 in P. lactiflora red outer-petal resulted in lighter petal color and decreased acetyl-CoA accumulation, and quantitative analysis detected that PlACLB2-silenced petals lost more anthocyanins than the control groups with a decrease of 31.0%, and the main pigment component cyanidin-3,5-O-diglucoside was reduced by 31.9%. …”

Datasheet1_Left ventricular structure and function following renal sympathetic denervation in patients with HFpEF: an echocardiographic 9-year long-term follow-up.docx by Alexander Vogt (375813)

“…We found a significant reduction of the HFA-PEFF score from 5.48 ± 0.51 points at baseline to 4.33 ± 1.53 points at the 9-year follow-up (P < 0.01). …”

Neural timescales increase with cognitive demands. by Isabel Raposo (21615517)

“…The individual values for panel B and D are included in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003232#pbio.3003232.s005" target="_blank">S2 Data</a>, Experiment 5 sheet and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003232#pbio.3003232.s007" target="_blank">S4 Data</a>, respectively.…”

Table_1_Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells.docx by Nunzia Mollo (6891068)

“…These effects, together with a significant increase of basal ATP content and oxygen consumption rate, and a significant decrease of reactive oxygen species (ROS) production, provide strong evidence of an overall improvement of mitochondria bioenergetics in trisomic cells. …”

VCP Inhibition by DBeQ effectively controls H1299 proliferation and migration while inducing apoptosis. by Kyla Walworth (3150936)

“…Data indicates that DBeQ treatment leads to a more significant (p<0.001) decrease in cell proliferation, as compared to NMS-873. …”