Data_Sheet_1_DNA Methylation-Based Age Prediction and Telomere Length Reveal an Accelerated Aging in Induced Sputum Cells Compared to Blood Leukocytes: A Pilot Study in COPD Patien... by Manuela Campisi (5387129)

“…Data on demographics, life style and occupational exposure, lung function, and clinical and blood parameters were collected. DNAmAge (67.4 ± 5.80 vs. 61.6 ± 5.40 years; p = 0.0003), AgeAcc (−4.5 ± 5.02 vs. −10.8 ± 3.50 years; p = 0.0003), and TL attrition (1.05 ± 0.35 vs. 1.48 ± 0.21 T/S; p = 0.0341) are higher in IS cells than in blood leukocytes in the same patients. …”

Genetic Variation in the <i>Staphylococcus aureus</i> 8325 Strain Lineage Revealed by Whole-Genome Sequencing by Kristoffer T. Bæk (464667)

“…Using an extensive strain pedigree analysis, we discovered that 8325-4 contains 16 single nucleotide polymorphisms (SNP) arising prior to the construction of RN4220. We identified 5 indels in 8325-4 compared with 8325. Three indels correspond to expected Φ11, 12, 13 excisions, one indel is explained by a sequence assembly artifact, and the final indel (Δ63bp) in the <i>spa-sarS</i> intergenic region is common to only a sub-lineage of 8325-4 strains including SH1000. …”

Data_Sheet_1_Dosing Time Matters? Nighttime vs. Daytime Administration of Nifedipine Gastrointestinal Therapeutic System (GITS) or Amlodipine on Non-dipper Hypertension: A Randomiz... by Jing Liu (38537)

“…<p>Background: Non-dipper hypertension is often characterized by a blunted decrease of nocturnal blood pressure (BP) and is associated with increased risk of target organ damage and cardiovascular (CV) events, while the optimal treatment strategy is yet to be established. …”

LDT-623 interferes with the hemozoin formation pathway within the digestive vacuole. by Letícia Tiburcio Ferreira (19964570)

Data_Sheet_1_Frequency-Specific Changes in the Fractional Amplitude of the Low-Frequency Fluctuations in the Default Mode Network in Medication-Free Patients With Bipolar II Depres... by Jun Zhou (6477)

“…Moreover, a positive association was found between the increase in slow 5 fALFF values (follow-up value minus the baseline values) in cluster D and the decrease in HDRS scores (baseline HDRS scores minus follow-up HDRS scores) at follow-up, and the same association between the increase in slow 5 fALFF values and the decrease in HDRS scores was found in cluster E.…”

Data_Sheet_1_Frequency-Specific Changes in the Fractional Amplitude of the Low-Frequency Fluctuations in the Default Mode Network in Medication-Free Patients With Bipolar II Depres... by Jun Zhou (6477)

“…Moreover, a positive association was found between the increase in slow 5 fALFF values (follow-up value minus the baseline values) in cluster D and the decrease in HDRS scores (baseline HDRS scores minus follow-up HDRS scores) at follow-up, and the same association between the increase in slow 5 fALFF values and the decrease in HDRS scores was found in cluster E.…”

table1_Effect of Liraglutide on Cardiometabolic Risk Profile in People with Coronary Artery Disease with or without Type 2 Diabetes: A Systematic Review and Meta-Analysis of Random... by Peyman Nowrouzi-Sohrabi (10489736)

“…Our findings presented as WMD and 95% CI showed a statistical significant decrease in hemoglobin A1c (HbA1c) [−0.36%; −0.47; −0.26, p < 0.001; I² = 0.0% (with 6 RCTs)], body mass index (BMI) [−0.61 kg/m²; −1.21; −0.01, p = 0.047; I² = 72.2% (with five RCTs)], and waist circumference [−2.41 cm; −3.47; −1.36, p < 0.001; I² = 0.0% (with three RCTs)]. …”

Image 1_L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China.tiff by Yanqin Li (499034)

“…RCS curves indicated an L-shaped association between TyG-BMI and self-rated mental health (p for non-linear = 0.033), with an inflection point of 204.3. Below this threshold, each 10-unit increase in TyG-BMI was associated with a 6% decrease in self-rated mental health risk (adjusted hazard ratio [aHR] = 0.94, 95% confidence interval [CI]: 0.90–0.99). …”

Image 2_L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China.tiff by Yanqin Li (499034)

“…RCS curves indicated an L-shaped association between TyG-BMI and self-rated mental health (p for non-linear = 0.033), with an inflection point of 204.3. Below this threshold, each 10-unit increase in TyG-BMI was associated with a 6% decrease in self-rated mental health risk (adjusted hazard ratio [aHR] = 0.94, 95% confidence interval [CI]: 0.90–0.99). …”

FIGURE 6 from D-2-HG Inhibits <i>IDH1^mut</i> Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation by Sean T. Pianka (18237413)

“…<b>C,</b> Decreased <i>ATF5</i> mRNA m6A content detected by <i>ATF5</i> qRT-PCR in the same <i>IDH1^mut</i> gliomas (<i>P</i> ≤ 0.008). …”

Presenting symptoms. by Tamrat Petros Elias (18536434)

“…Systematic random sampling was used to select a total of 400 patients. A structured questionnaire developed from the case report form for PACS of the World Health Organization (WHO) was used. …”

Comorbidity pattern of patients. by Tamrat Petros Elias (18536434)

“…Systematic random sampling was used to select a total of 400 patients. A structured questionnaire developed from the case report form for PACS of the World Health Organization (WHO) was used. …”

Patient selection for this study. by Tamrat Petros Elias (18536434)

“…Systematic random sampling was used to select a total of 400 patients. A structured questionnaire developed from the case report form for PACS of the World Health Organization (WHO) was used. …”

Treatment consequence and adverse events of cyclin-dependent kinase 4/6 inhibitors on patients with hormone receptor-positive, HER2-negative metastatic breast cancer: a systematic... by Hsiang-Ying Wu (22212274)

“…The meta-analysis followed PRISMA guidelines and used RevMan 5.3 to conduct the analysis.</p> <p>Eleven clinical trials published between 2015 and 2022 were included in our meta-analysis, with a total of 5572 eligible patients. …”

Table_1_Impact of Elevated CO2 and Reducing the Source-Sink Ratio by Partial Defoliation on Rice Grain Quality – A 3-Year Free-Air CO2 Enrichment Study.DOCX by Bo Gao (106513)

“…Markedly, eCO₂ increased peak viscosity (+ 2.9%) and minimum viscosity (+ 3.8%) but decreased setback (−96.1%) of powder rice and increased the appearance (+ 4.5%), stickiness (+ 3.5%) and balance degree (+ 4.8%) of cooked rice, while decreasing the hardness (−6.7%), resulting in better palatability (+ 4.0%). …”

Data_Sheet_1_Age- and Sex-Related Cortical Gray Matter Volume Differences in Adolescent Cannabis Users: A Systematic Review and Meta-Analysis of Voxel-Based Morphometry Studies.doc... by Aliyah Allick (11774372)

“…Recent imaging studies have identified neuroanatomical differences between adult cannabis users and controls that are more prominent in early-onset users. Other studies point to sex-dependent effects of cannabis.</p><p>Methods: A systematic review following PRISMA guidelines and subsequent effect-size seed-based d mapping (SDM) meta-analyses were conducted to investigate relationships between age (across the 12-to-21-year-old developmental window), sex, and gray matter volume (GMV) differences between cannabis using (CU) and typically developing (TD) youth.…”

Drive-up INR testing and phone-based consultations service during COVID-19 pandemic in a pharmacist-lead anticoagulation clinic in Qatar: Monitoring, clinical, resource utilization... by Alhmoud, Eman N.

“…Methods: The study comprised of two components: a retrospective cohort study of all eligible patients who attended anticoagulation clinic over 1-year period (6 months before and 6 months after service transition) and a cross-sectional survey of eligible patients who agreed to provide data about their satisfaction with the new service. …”
Get full text
Get full text
Get full text

Data_Sheet_1_Bone and Lean Mass Loss and Cognitive Impairment for Healthy Elder Adults: Analysis of the Nutrition and Health Survey in Taiwan 2013–2016 and a Validation Study With... by Sheng-Feng Lin (9591995)

“…With increasing in the severity of cognitive impairment, the bone marrow density and lean mass consistently showed the trend of decreasing values. In the GLMMs, a significant association existed between the decrease of the bone mineral density (BMD) and the Mini-Mental State Examination (MMSE) (β = 5.819 scores per g/cm² decrease, p = 0.0305) with adjustment of the age, sex, and physical activity. …”

Data_Sheet_1_Bone and Lean Mass Loss and Cognitive Impairment for Healthy Elder Adults: Analysis of the Nutrition and Health Survey in Taiwan 2013–2016 and a Validation Study With... by Sheng-Feng Lin (9591995)

“…With increasing in the severity of cognitive impairment, the bone marrow density and lean mass consistently showed the trend of decreasing values. In the GLMMs, a significant association existed between the decrease of the bone mineral density (BMD) and the Mini-Mental State Examination (MMSE) (β = 5.819 scores per g/cm² decrease, p = 0.0305) with adjustment of the age, sex, and physical activity. …”

Data_Sheet_1_Fenofibrate enhances lipid deposition via modulating PPARγ, SREBP-1c, and gut microbiota in ob/ob mice fed a high-fat diet.ZIP by Ying Zhang (40767)

“…As a PPARα agonist, fenofibrate intervention significantly increased the expression of PPARα protein in the liver by 46.3% and enhanced the expression of LDLR protein by 3.7-fold. …”