Image_4_GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer’s Disease.tif by Jahirul Islam (11280516)

“…Furthermore, TDCA enhanced phagocytosis of Aβ and decreased the number of Aβ plaques in the brains of 5x Familial Alzheimer’s disease (5xFAD) mice. …”

Image_11_GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer’s Disease.tif by Jahirul Islam (11280516)

“…Furthermore, TDCA enhanced phagocytosis of Aβ and decreased the number of Aβ plaques in the brains of 5x Familial Alzheimer’s disease (5xFAD) mice. …”

Image_6_GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer’s Disease.tif by Jahirul Islam (11280516)

“…Furthermore, TDCA enhanced phagocytosis of Aβ and decreased the number of Aβ plaques in the brains of 5x Familial Alzheimer’s disease (5xFAD) mice. …”

Image_10_GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer’s Disease.tif by Jahirul Islam (11280516)

“…Furthermore, TDCA enhanced phagocytosis of Aβ and decreased the number of Aβ plaques in the brains of 5x Familial Alzheimer’s disease (5xFAD) mice. …”

Effect of precipitation frequency on litter decomposition of three annual species (<i>Setaria viridis, Artemisia sacrorum</i>, and <i>Chenopodium acuminatum</i>) in a semi-arid san... by Yongqing Luo (5233820)

“…We hypothesized that low <i>PF</i> would decrease decomposition rates. We performed a litterbag decomposition experiment with litter of three annual species at three depths (aboveground litter, litter at 0–10 and 10–20 cm below the surface). …”

Data Sheet 1_Perspectives in newborn screening for SCID in Japan. Case report: newborn screening identified X-linked severe combined immunodeficiency with a novel IL2RG variant.doc... by Shiro Beppu (20294304)

“…Flow cytometric measurement testing revealed a decrease in γc protein expression in the B lymphocytes and NK lymphocytes. …”

Data_Sheet_1_The correlation between red cell distribution width to albumin ratio and all-cause mortality in critically ill patients with rheumatic diseases: a population-based ret... by Lijuan Yin (764679)

“…The ROC curves demonstrated that an optimal cut-off value of RAR for predicting 90-days mortality was determined to be 5.453, yielding a sensitivity of 61.5% and specificity of 60.3%.…”

Table_1_Changes in Physiological Parameters, Lipid Metabolism, and Expression of MicroRNAs in Genetically Improved Farmed Tilapia (Oreochromis niloticus) With Fatty Liver Induced b... by Yi-Fan Tao (5906243)

“…The transcript levels of hepatic SCD and ELOVL6 were decreased and that of hepatic SRD5A2 was increased in GIFT fed a HFD. …”

Visualization of differentially abundant metabolites in HG-cultured BeWo CT cells. by Zachary J. W. Easton (14808827)

“…<p><b>A</b> volcano plot was constructed to visualize the differentially abundant metabolites in HG-cultured BeWo CT cells ((≥ ±1.5-fold change, p<0.05, n = 5/group). …”

Hematological and biochemical parameters in Spotted Paca (Cuniculus paca) undergoing pharmacological restraint and general anesthesia by R.A.R. Uscategui (5839283)

“…In conclusion, chemical restraint with ketamine/midazolam association causes a slight decrease in blood cellular components. …”

Data_Sheet_1_Global, regional, and national burden and trends analysis of gallbladder and biliary tract cancer from 1990 to 2019 and predictions to 2030: a systematic analysis for... by Jiao Su (560028)

“…</p>Results<p>From 1990 to 2019, the number of incident cases, prevalent cases, deaths, and DALYs worldwide significantly increased by 1.85-fold, 1.92-fold, 1.82-fold, and 1.68-fold, respectively. …”

DataSheet_1_Integrated genomic, transcriptomic, and epigenetic analyses identify a leukotriene synthesis-related M2 macrophage gene signature that predicts prognosis and treatment... by Hang Ji (2432434)

“…Further distilling the pathway members resulted in a leukotriene synthesis-related gene signature (Macro index), including PIK3R5, PIK3R6, ALOX5, ALOX5AP, and ALOX15B, that was primarily expressed by monocytes/macrophages. …”

Table_1_Presenting symptoms as prognostic measures of mental health recovery among service members with concussion.docx by Rosemay A. Remigio-Baker (7864583)

“…The outcomes, clinically-relevant decreases in depressive symptoms (assessed by the 8-item Patient Health Questionnaire, PHQ-8) and PTSD symptoms (assessed by the PTSD Checklist for DSM-5, PCL-5), were defined as a decrease in PHQ-8 > 5 and PCL-5 > 7, respectively. …”

Image_1_Presenting symptoms as prognostic measures of mental health recovery among service members with concussion.pdf by Rosemay A. Remigio-Baker (7864583)

“…The outcomes, clinically-relevant decreases in depressive symptoms (assessed by the 8-item Patient Health Questionnaire, PHQ-8) and PTSD symptoms (assessed by the PTSD Checklist for DSM-5, PCL-5), were defined as a decrease in PHQ-8 > 5 and PCL-5 > 7, respectively. …”

Model-based analysis of diversification rates in Apameini moths. by Emmanuel F. A. Toussaint (147463)

“…<p>Varying-rate model considers all possible bipartitions of tree and finds bipartition giving the highest likelihood when net diversification rates are optimized separately to each partition. Decreasing-rate model assumes that previously recovered (with varying-rate model) shift point node have retained the ancestral diversification rate present at the root node.…”

Data_Sheet_1_Ultrasound-guided anterior iliopsoas muscle space block effectively reduces intraoperative hypotension in elderly adults undergoing hip surgery: A randomised controlle... by Qingyu Teng (14490755)

“…</p>Results<p>Compared to the posterior group, the iliopsoas space block group had a decreased median frequency of IOH [1.09 (0–2. 14) vs. 3 (1.6–4.8), p = 0.001, respectively] along with lower absolute [5 (0–10) min] and relative [minutes below systolic blood pressure of 100 mmHg in % of total anaesthesia time, 6.67 (0–7.65)] duration of IOH compared to the posterior group [35 (10–45) min, p = 0.008; 37.6 (12.99–66.18), p = 0.004, respectively]. …”

Data_Sheet_1_miR-221-3p Drives the Shift of M2-Macrophages to a Pro-Inflammatory Function by Suppressing JAK3/STAT3 Activation.pdf by Lilian Quero (2346979)

“…TLR4-stimulation of M1- and M2-macrophages resulted in downregulation of miR-221-3p, but upregulation of miR-155-5p. M2-macrophages transfected with miR-221-3p mimics secreted less IL-10 and CXCL13 but more IL-6 and IL-8, exhibited downregulation of JAK3 protein and decreased pSTAT3 activation. …”

Data_Sheet_1_Dynamics of Serum Tumor Markers Can Serve as a Prognostic Biomarker for Chinese Advanced Non-small Cell Lung Cancer Patients Treated With Immune Checkpoint Inhibitors.... by Zhibo Zhang (8956400)

“…</p><p>Methods: We initiated a longitudinal prospective study on advanced NSCLC patients treated with PD-1/PD-L1 inhibitors in Chinese PLA general hospital (Beijing, China). …”

Time plots of continuous EE data calculated using the Weir RQ^- method and its correspondence to the standard Weir RQ⁺ method and RQ in a single mouse. by Karl J. Kaiyala (310719)

“…Mean ± 2 SD limits are indicated. (C) RQ. Median, 97.5th and 25th percentiles are indicated. Note that the Δ EE trace indicates remarkably little error between the RQ^- and RQ⁺ equations, but that it tends to rise to its most extreme values as RQ decreases. …”

Data_Sheet_1_The effect of omega-3 fatty acids and its combination with statins on lipid profile in patients with hypertriglyceridemia: A systematic review and meta-analysis of ran... by Yunjiao Yang (4966963)

“…When OM3-FA was used as monotherapy compared with placebo, it significantly decreased TG (MD: −39.81, 95% CI: −54.94 to −24.69; p < 0.001), TC (MD: −2.98, 95% CI: −5.72 to −0.25, p = 0.03), very low-density lipoprotein cholesterol (VLDL-C) (MD: −25.12, 95% CI: −37.09 to −13.14; p < 0.001), and non-high-density lipoprotein cholesterol (non-HDL-C) levels (MD: −5.42, 95% CI: −8.06 to−2.78; p < 0.001), and greatly increased LDL-C (MD: 9.10, 95% CI: 4.27 to 13.94; p < 0.001) and HDL levels (MD: 1.60, 95% CI: 0.06 to 3.15; p = 0.04). …”