Increased podocytes death and reduced podocytes adhesion cultured with conditioned medium of mesangial cells exposed to cIgA1 from IgAN patients (IgAN-HMCM) and rhTGF-β1 together w... by Li Zhu (67404)

“…The decreased podocyte adhesion, induced by IgAN-HMCM or rhTGF-β1 (2ng/ml) together with rhCXCL1 (2ng/ml) could be partially rescued by simultaneous incubation with 0.5ug/ml blocking antibody against CXCR2 (symbol # represented p<0.05 compared to without CXCR2 blocking antibody).…”

Gross images of P1 urogenital blocks and histological sections of P1 kidneys from control (A–D, H, I) and <i>PRR</i>^UB−/− (E–L, J–M) mice. by Renfang Song (582909)

Supplementary Material for: Enhanced Neuroprotective Effects of Combination Therapy with Bone Marrow-Derived Mesenchymal Stem Cells and <b><i>Ginkgo biloba</i></b> Extract (EGb761)... by Hao F. (4155400)

<b>Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional </b><b><i>WFS1</i></b><b> varian... by Silvia Torchio (611349)

Data_Sheet_1_Anti-drug Antibodies Against a Novel Humanized Anti-CD20 Antibody Impair Its Therapeutic Effect on Primary Biliary Cholangitis in Human CD20- and FcγR-Expressing Mice.... by Yuki Moritoki (706165)

“…Accompanying these changes was a dramatic reduction in anti-mitochondrial antibodies (AMAs), interleukin (IL)-12p40 and IL-5, and elevated levels of the anti-inflammatory chemokine CXCL1/KC. …”

Table 1_Short-term caloric restriction or resveratrol supplementation alters large-scale brain network connectivity in male and female rats.docx by Judith R. A. van Rooij (20655404)

“…Furthermore, we found that both CR or Rsv supplementation induce a female-specific decrease of FC between the subcortical network and hippocampal network, and between the subcortical network and lateral cortical network. …”

c-Myc Represses Tumor-Suppressive microRNAs, let-7a, miR-16 and miR-29b, and Induces Cyclin D2-Mediated Cell Proliferation in Ewing’s Sarcoma Cell Line by Masanori Kawano (798368)

“…We also demonstrated that c-Myc-siRNA treatment of ES cells was associated with the decreased expression of CCND2 as a down-stream of three miRNAs. …”

Datasheet1_Impact of hypertensive heart disease, risk factors, and age-period-cohort models across 204 nations and regions from 1990 to 2019: a global perspective from the 2019 glo... by Guoliang Gao (2910503)

“…The APC model revealed an association between mortality rates and age, with a decreasing mortality risk over time and improved survival rates for a later birth cohort.…”

Age-period-cohort analysis of global rabies incidence (1990-2021). by Chenxuan Yang (8667693)

Image_2_The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-depe... by James E. Blevins (11405813)

“…We hypothesized that GEP44 reduces energy intake and BW primarily through a GLP-1R dependent mechanism. To test this hypothesis, GLP-1R^+/+ mice and GLP-1R null (GLP-1R^-/-) mice were fed a high fat diet for 4 months to elicit diet-induced obesity prior to undergoing a sequential 3-day vehicle period, 3-day drug treatment (5, 10, 20 or 50 nmol/kg; GEP44 vs the selective GLP-1R agonist, exendin-4) and a 3-day washout. …”

Image_1_The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-depe... by James E. Blevins (11405813)

“…We hypothesized that GEP44 reduces energy intake and BW primarily through a GLP-1R dependent mechanism. To test this hypothesis, GLP-1R^+/+ mice and GLP-1R null (GLP-1R^-/-) mice were fed a high fat diet for 4 months to elicit diet-induced obesity prior to undergoing a sequential 3-day vehicle period, 3-day drug treatment (5, 10, 20 or 50 nmol/kg; GEP44 vs the selective GLP-1R agonist, exendin-4) and a 3-day washout. …”

High-throughput screening and <i>in vitro</i> evaluation of CSB-0914; a novel small molecule NF-κB inhibitor attenuating inflammatory responses through NF-κB, Nrf2 and HO-1 cross-t... by Mesfer Al Shahrani (13774273)

Mean values of heart rate (upper panel) and mean blood pressure (lower panel) at 5 sec intervals in the supine position, during early head-up tilt (HUT), and during tilt-induced (p... by Christoph Schroeder (341105)

Increase in Red Blood Cell-Nitric Oxide Synthase Dependent Nitric Oxide Production during Red Blood Cell Aging in Health and Disease: A Study on Age Dependent Changes of Rheologic... by Daniel Alexander Bizjak (728303)

Table_1_The non-linear link between non-high-density lipoprotein to high-density lipoprotein ratio and the risk of stroke in middle-aged and older adults in Chinese: a prospective... by Lanbo Wang (4473781)

“…Employing a two-piece Cox proportional hazards regression model and a recursive algorithm, we determined an inflection point of 2.685 for the non-HDL-c/HDL-c ratio. …”

Inhibition of <i>RPL22B</i> splicing by Rpl22p in the nucleus can be reproduced <i>in vitro</i> and may involve a repression of the co-transcriptional U1 snRNP recruitment <i>in</i... by Jason Gabunilas (550398)

“…<i>SCR1</i> was used as a loading control. <b>B.</b> Northern blot analysis of the <i>mex67-5</i> strain similar to panel A with the addition of the genetic inactivation of <i>RRP6</i>. …”

(A) Location of the study site, sea ice extent and GPS tracks from (B) 2012 and (C) 2014 and (D) 75% kernel contours of resting and foraging positions in 2012 (green), and 2014 (pi... by Françoise Amélineau (3149880)

“…<p>1A: General map situating Ukaleqarteq (red dot) and the location of the studied area (red rectangle) represented in Figs 1B, 1C, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0157764#pone.0157764.g005" target="_blank">5A</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0157764#pone.0157764.s001" target="_blank">S1</a>. 1B and 1C: GPS tracks: red dots correspond to foraging or resting (speed <10 km.h^-1) and black dots to travelling (speed >10 km.h^-1). …”

Data_Sheet_1_Comparison of Postnatal Growth Charts of Singleton Preterm and Term Infants Using World Health Organization Standards at 40–160 Weeks Postmenstrual Age: A Chinese Sing... by Li Zhang (8200)

“…This retrospective cohort study, conducted in the First Affiliated Hospital of Shandong First Medical University in Jinan China, aimed to compare the postnatal growth charts of singleton preterm and term infants using WHO standards at 40–160 weeks postmenstrual age (PMA). A total of 5,459 and 15,185 sets of longitudinal measurements [length/height, weight, head circumference (HC), and body mass index (BMI)] from birth to 160 weeks PMA were used to construct growth charts for 559 singleton preterm (mean PMA at birth, 33.84 weeks) and 1,596 singleton term infants (born at 40 weeks PMA), respectively, using the Generalized Additive Models for Location, Scale, and Shape (GAMLSS) method. …”

<b>Data supporting the findings of Tian et al. (2024) </b><b>Multi-ecosystem services</b><b> differently affected by over-canopy and understory nitrogen additions in a typical subt... by yang tian (17858954)

Synthesis, Crystal Structure and Magnetic Characterization of a Series of Cu^II–Ln^III Heterometallic [Ln = La, Ce, Pr, Nd and Sm) Metal–Organic Compounds with... by Pau Díaz-Gallifa (1791856)

“…This phase transition is accompanied by a compression of the crystallographic <i>b</i>-axis in the range 2.4 to 2.8 Å with the consequent decrease of the unit cell volume from 9.5% to 12%. …”