DataSheet1_Ultrasound-induced cavitation renders prostate cancer cells susceptible to hyperthermia: Analysis of potential cellular and molecular mechanisms.ZIP by Shaonan Hu (10728498)

“…Immunofluorescence microscopy and flow cytometry were performed to determine the distribution and expression of 5α-reductase (SRD5A).</p><p>Results: Short FUS shots with cavitation (FUS-Cav) in combination with HT resulted in, respectively, a 2.2, 2.3, and 2.8-fold decrease (LNCap) and a 2.0, 1.5, and 1.6-fold decrease (PC-3) in the clonogenic survival, cell invasiveness and metabolic activity of prostate cancer cells when compared to HT alone. …”

Cellular stress response-associated RNA changes and inferred signaling pathways. by Renée Deehan (326438)

“…<p>(<b>A</b>) Biologic processes associated with the cellular stress response inferred to increase or decrease upon treatment with aleglitazar, tesaglitazar or Pio/Feno. …”

Effect of selection pressure, group size, interaction between groups and learning costs on the mean number of cultural traits per individual. by Carolin Vegvari (516405)

“…Results are grouped according to selection differential (x-axis). a, b: Higher selection pressure can increase the number of traits per individual up to a certain point (selection differential 0.5), but can lead to a decrease if it is too high (1.0). …”

Antiviral therapies and viral strain affect COVID-19 severity. by Chrysovalantis Voutouri (612840)

“…K_in values estimated to correspond to current antivirals are shown in the plot. Fold-decrease in antibody affinity for the virus is on horizontal axis, and values thought to correspond to currently known variants (all omicron variants from BA.1 to BA 4/5) are listed for reference. …”

Maternal levels of endocrine disrupting chemicals in the first trimester of pregnancy are associated with infant cord blood DNA methylation by Luke Montrose (5116049)

“…For example, urinary BPA exposure was associated with a 1.35 (95%CI: −2.69, −0.01) percentage point decrease in <i>IGF2</i> methylation and a 1.22 (95%CI: −2.27, −0.16) percentage point decrease in <i>PPARA</i> methylation in females only. …”

The effect of protein concentration on background and detection limits by Brian B Haab (3321)

“…</p><p>Copyright © 2001 BioMed Central Ltd</p> Six antigen mixes were added to fetal calf serum (FCS) solutions to produce a 10-fold and 100-fold increase in total protein concentration and a corresponding decrease in partial concentration of the antigens. …”

Metabolic profiling by tandem mass spectrometry reveals distinct metabolite signatures of cells exposed to pro-inflammatory cytokines vs. the apoptotic inducer camptothecin. by J. Jason Collier (130356)

“…Metabolite concentration was measured by mass spectrometry with values displayed as fold change relative to control. The represent values given in log₂, so that “3.00” is a minimum of an 8-fold increase, while “−3.00” is a minimum of an 8-fold decrease. …”

PIN1 endocytosis is inhibited in the lobe region by the ROP2 pathway in PCs. by Shingo Nagawa (173932)

“…Coexpressing CA-ROP2 suppressed both vesicle formation and decrease of PM signal in <i>rop4 R2i</i> cells (<i>n</i> = 5). …”

Validation of host-specific proteins involved in regulating Mtb infection. by Shilpi Jayaswal (250300)

“…Panel B shows a scatter plot comparing the fold deviation of the mean values for the individual points in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000839#ppat-1000839-g001" target="_blank">Figure 1A</a>, relative to SD of the mean CFU values for the corresponding controls.…”

Distribution of altered Gene ontology (GO) terms in the hippocampus after BCCAO. by Jihye Bang (439682)

“…<p>(A) Differentially-expressed genes with a 2-fold increase and decrease at each time point after BCCAO were subjected to analysis using GoMiner. …”

List of 36 potential BAT genes identified by the combinatorial approach. by George S. Hussey (110417)

“…<p>Despite minor changes in total RNA levels, the target mRNAs display a >5 fold increase in polyribosome association in NMuMG cells post TGFβ treatment compared to E1KD cells where the target mRNAs display constitutive translational activation. …”

Downregulation of detoxification genes in villi lacking functional pRb and/or E2F1-2-3 proteins. by Maria Teresa Sáenz Robles (201330)

“…Samples were normalized against an endogenous control (Adh and/or Rpl5). c) Cyp3A protein levels decrease in samples lacking pRb. …”

High-resolution SEM analysis of tip links. by Kateri J. Spinelli (293686)

“…(e, f) Bundles treated with 5 mM EGTA for 5 min showed a marked decrease in bundle Fluo-4 fluorescence and a significant reduction in the number of tip links (g, h). …”

Data Sheet 1_Amyloid-induced mitochondrial network disruption in neurons monitored by STED super-resolution imaging.pdf by Iuliia Golovynska (18880049)

“…As a result, the volume and surface area per mitochondrion decrease by 6-fold and 4-fold, respectively. …”

Timed data for onset and survival. by Alexandre Henriques (359791)

“…(A) Onset of weight decrease was defined as a drop of 5% of the mouse maximal weight. …”

Change in LRAGG in response to IFN Treatment in patients with liver fibrosis. by Anne Lamontagne (418004)

“…(B) In contrast, those patients who responded to IFN and cleared their HCV and started had greater than 5-fold increase over normal at the start of treatment show a significant decrease following treatment (P<0.05) (C). …”

Results from RNAi screen against 1920 <i>Drosophila</i> gene products. by Adam Peltan (112024)

“…Green shading indicates hits that caused a significant increase in phagocytosis. Red shading indicates hits that caused a significant decrease in phagocytosis. …”

Loss of Myoferlin Redirects Breast Cancer Cell Motility towards Collective Migration by Leonithas I. Volakis (155515)

“…MDA-231^MYOF-KD cells exhibited a 2-fold decrease in cell stiffness, a 2-fold increase in cell-substrate adhesion and a 1.5-fold decrease in traction force generation. …”

AZ2.0 by Binay Panda (768771)

“…The updated genome assembly (v2.0) yielded 3- and 3.5-fold increase in N50 and N75, <br>respectively; 2.6-fold decrease in the total number of scaffolds; 1.25-fold increase in the number of <br>valid transcriptome alignments; 13.4-fold less mis-assembly and 1.85-fold increase in the <br>percentage repeat, resulted due to removal of mis-assembly and closure of gaps fromover the earlier <br>assembly (v1.0). …”

Intracellular LF82 multiplication requires stress responses. by Gaëlle Demarre (249248)

“…Horizontal lines indicate viability decrease by 2, 5 and 10 fold compared to WT LF82. Data were analyzed using a Student’s <i>t</i> test: * <i>P</i> <0.05, ** <i>P</i> <0.01, *** <i>P</i> <0.001, **** <i>P</i> <0.0001 (black stars correspond to mutant vs WT, blue stars correspond to mutant vs its complementation).…”