Curcumin Improves the Tumoricidal Effect of Mitomycin C by Suppressing ABCG2 Expression in Stem Cell-Like Breast Cancer Cells by Qianmei Zhou (787066)

“…Curcumin improved the sensitivity of paclitaxel, cisplatin, and doxorubicin in breast cancer cell lines MCF-7 and MDA-MB-231, as shown by the more than 2-fold decrease in the half-maximal inhibitory concentration of these chemotherapeutic agents. …”

DataSheet_1_Phytoplankton photophysiology varies depending on nitrogen and light availability at the subsurface chlorophyll maximum in the northern Chukchi Sea.docx by Eunho Ko (14004480)

“…This decrease was accompanied by a marked decrease in the fraction of microplankton, which are known to be susceptible to nutrient limitation. …”

Analysis of pSer2 Pol2 intragenic occupancy in response to PULS or CONS after 140 min and 180 min. by Benjamin P. Flynn (11256176)

“…Horizontal bar graph indicates the number of genes enriched by each CORT infused time point. (F) Histogram of tag density distribution -5 kb and +15 kb from the TSS of pSer2 Pol2 differentially regulated genes on the sense strand within coding regions > 10 kb in response to a CORT infused time point. …”

Effects of S1P receptor modulators on uptake of FITC-labeled dextran and PI3K activity. by Lukasz Japtok (299762)

“…Values of the densitometric analysis are expressed as x-fold decrease of p-Akt formation compared to untreated cells ± SEM from three experiments. …”

Intrinsic DNA binding affinity differences for ETS1 and ELF1. by Peter C. Hollenhorst (255761)

“…The K_D of ETS1 and ELF1 for the ETS consensus sequence was 1.7×10⁻⁹ and 1.7×10⁻¹⁰ M, respectively. The fold decrease in affinity due to the A to T change, the C to A change, and the combination of both changes were 1.0, 1.5, and 2.4 for ETS1 and 3.6, 1.9, and 18.3 for ELF1, respectively.…”

PRSS56 activity is required during both the vision-independent and dependent stages of ocular growth. by Seyyedhassan Paylakhi (4951933)

“…(<b>E</b>-<b>G</b>) OCT measurements demonstrate that following tamoxifen injection at P13 (a time point when the eyes are open), <i>Prss56</i>^<i>F/F</i><i>; Ubc-Cre</i>^<i>ERT2</i> mice display a slight but significant decrease in ocular axial length (<b>E</b>) and increase in retinal thickness (<b>F</b>) at P30 and P45. …”

Complete Suppression of Blinking and Reduced Photobleaching in Single MEH-PPV Chains in Solution by Suguru Onda (1281132)

“…Adsorption of the chains onto a substrate in the solution leads to 34% decrease in fluorescence intensity (quantum efficiency), five-fold increase in the rate of photobleaching and appearance of blinking. …”

Supplementary file 3_Impact of iron chelation therapy on mitochondrial function, vascular integrity and inflammation in transfusion-dependent myelodysplastic syndromes.docx by Regina García-Delgado (22589807)

“…</p>Results<p>Chelation therapy was associated with a ~55% decrease in serum ferritin and robust redox recovery: leukocyte H₂O₂ and superoxide decreased ~3.8-fold and ~3.2-fold, respectively (both p<0.0001), intracellular glutathione increased ~3.3-fold (p<0.0001), and mitochondrial membrane potential rose ~2.6-fold (p<0.0001). …”

Supplementary file 1_Impact of iron chelation therapy on mitochondrial function, vascular integrity and inflammation in transfusion-dependent myelodysplastic syndromes.docx by Regina García-Delgado (22589807)

“…</p>Results<p>Chelation therapy was associated with a ~55% decrease in serum ferritin and robust redox recovery: leukocyte H₂O₂ and superoxide decreased ~3.8-fold and ~3.2-fold, respectively (both p<0.0001), intracellular glutathione increased ~3.3-fold (p<0.0001), and mitochondrial membrane potential rose ~2.6-fold (p<0.0001). …”

Supplementary file 2_Impact of iron chelation therapy on mitochondrial function, vascular integrity and inflammation in transfusion-dependent myelodysplastic syndromes.docx by Regina García-Delgado (22589807)

“…</p>Results<p>Chelation therapy was associated with a ~55% decrease in serum ferritin and robust redox recovery: leukocyte H₂O₂ and superoxide decreased ~3.8-fold and ~3.2-fold, respectively (both p<0.0001), intracellular glutathione increased ~3.3-fold (p<0.0001), and mitochondrial membrane potential rose ~2.6-fold (p<0.0001). …”

Data Sheet 1_Impact of iron chelation therapy on mitochondrial function, vascular integrity and inflammation in transfusion-dependent myelodysplastic syndromes.pdf by Regina García-Delgado (22589807)

“…</p>Results<p>Chelation therapy was associated with a ~55% decrease in serum ferritin and robust redox recovery: leukocyte H₂O₂ and superoxide decreased ~3.8-fold and ~3.2-fold, respectively (both p<0.0001), intracellular glutathione increased ~3.3-fold (p<0.0001), and mitochondrial membrane potential rose ~2.6-fold (p<0.0001). …”

Calf circumference: clinical validation for evaluation of muscle mass in the elderly by Valéria Pagotto (4830771)

“…Results: The most accurate cut-off points for detecting decreased muscle mass in the elderly were 34 cm for men (sensitivity: 71.5%, specificity: 77.4%) and 33 cm for women (sensitivity: 80.0%; specificity: 84.6%). …”

Predicting alternans in the Ca²⁺-driven model with positive Ca²⁺ to APD coupling during ramp pacing. by Mathieu Lemay (330649)

“…<p><i>A</i>: CL, APD, DI, λ_alt and S_S1S2 during the ramp decrease of CL with superimposed variations (SD = 1 ms). λ_alt and S_S1S2 were estimated every 15 beats using a 2^nd order ARMA model from APDs and CLs in a window spanning the 30 preceding cycles. …”

12-HETE induces phosphorylation of VEGF-R2 and dephosphorylation of protein tyrosine phosphatase (PTP) SHP1 in REC. by Amira Othman (380131)

“…<p>Western blotting analysis (A) demonstrated significant increase in the level of pVEGF-R2 after 5 and 60 minutes from the beginning of treatment with 12-HETE. …”

Depletion of SufT results in reduced OCR and ECAR. by Ashutosh Tripathi (2827796)

“…<p>(A) A change in % oxygen consumption rate (% OCR) and (B) % extra cellular acidification rate (% ECAR) of SufT-KD strain precultured for 72 h in the presence (+ATc) or absence (–ATc) of ATc and was measured after injection of 5 mM glucose (Glc) and 5 μM CCCP indicated by dotted lines. …”

Measured influence and the influence ratio. by Keiji Ota (7352777)

“…We order the sample points for each sample point from 1 (the lowest) to either 5 or 30 (the highest) depending on sample size. …”

Beta cell mass and apoptosis in mice treated with STZ alone, STZ + PPAG or STZ + exendin-4. by Imane Song (811832)

“…One injection of STZ (N = 13) or vehicle (N = 5) was given at time point 0 hour. Thirty hours after STZ injection, beta cell mass (A) was measured. …”

Image1_Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data.JPEG by Athanasios Chamzas (19699780)

“…The proposed titration strategy, with three dose adjustments based on trough levels of tacrolimus, increased the proportion of patients within the target range (10–12 ng/mL) more than 2.5-fold and decreased the proportion of patients outside the therapeutic window by 50% after the first week of treatment.…”

Table2_Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data.DOCX by Athanasios Chamzas (19699780)

“…The proposed titration strategy, with three dose adjustments based on trough levels of tacrolimus, increased the proportion of patients within the target range (10–12 ng/mL) more than 2.5-fold and decreased the proportion of patients outside the therapeutic window by 50% after the first week of treatment.…”

Table1_Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data.DOCX by Athanasios Chamzas (19699780)

“…The proposed titration strategy, with three dose adjustments based on trough levels of tacrolimus, increased the proportion of patients within the target range (10–12 ng/mL) more than 2.5-fold and decreased the proportion of patients outside the therapeutic window by 50% after the first week of treatment.…”