Stereoselective Alkali-Metal Catalysts for Highly Isotactic Poly(<i>rac</i>-lactide) Synthesis by Yangyang Sun (1446925)

“…The isoselective mechanism is chain-end control through the analysis of the stereoerrors in the microstructure of a final polymer; thus, isotactic multiblock structure polymers are obtained, and the highest melt point can reach 192.5 °C. …”

Standard and FPG-modified alkaline comet assay. by Elisa Coluzzi (651262)

“…DNA damage increases in a dose dependent manner after 1 hr treatment. We observed a time-dependent decrease of genomic damage to the control value 15 and 24 hrs after treatment. …”

Synergistic activity of proinflammatory cytokines on inhibition of KDM expression by NHEK. by Hanitriniaina Rabeony (596171)

“…Quantitative RT-PCR analysis was carried out on total RNA from 4 independent NHEK cultures. mRNA expression levels for cytokeratin 10 (CK10), cytokeratin 1 (CK1), desmoglein 1 (DSG1), desmocollin 1 (DSC1), fatty acid binding protein 5 (FABP5), calmodulin-like skin protein (CLSP), loricrin (LOR) and filaggrin (FLG) were normalized using GAPDH housekeeping gene and expressed as the fold decrease under unstimulated cultures. …”

BriX clustering statistics. by Lies Baeten (46413)

“…<p>(A) Effect of increasing RMSD threshold. Shown is the number of BriX classes (circles) and the percentage of classified fragments (squares) in function of the RMSD threshold (0.5–1.0 Angstrom) used during the clustering for fragments containing 7 residues. …”

Effects of variation in pDC number and activation status. by Gennady Bocharov (67777)

“…<p>(A) Virus kinetics in spleen following infection with low (5×10¹ pfu), intermediate (5×10³ pfu) and high (5×10⁵ pfu) dose infections under conditions of varying pDC numbers per spleen. …”

RDP delivers plasmid pVAX-BDNF into the brain and gene expression. by Ailing Fu (396429)

“…The mice were intravenously injected with 40 µg complexes of DNA and plasmid, and the BDNF levels were detected on day 0. 1, 3, 5, 7 after injection. (E), Transient decrease of BDNF level in the brain. …”

Prevalence of <i>S</i>. <i>haematobium</i> infection and heavy infection (dashed) by treatment over time (9–12 year-old-cross section only) and by study arm with 95% CI. by Anna E. Phillips (4050331)

“…Prevalence and heavy infection levels decrease over time in all arms, with the exception of arm 3 and 5 following two consecutive holiday years where infection levels appear to increase where communities were not treated for a two year period.…”

Difference and Equilibrium spectra and modelling of the putative R and M absorption spectra. by Ludovic S. Mure (262696)

“…Consistent with typical difference spectra of invertebrates, the response function (5-degree polynomial, R² = 0.91) shows two domains: a decrease in the response between 400–515 nm (min = 466 nm) and an increase in constriction for longer wavelengths (515–650 nm, max = 592 nm). …”

Indirect Restoration Thickness and Time after Light-Activation Effects on Degree of Conversion of Resin Cement by Ana Paula Almeida Ayres (12791726)

“…Four thicknesses (0.5, 1.0, 1.5 or 2.0 mm) of each indirect material were analyzed, and the light-activation was performed using a blue LED light. …”

Mice lacking RPMs exhibit wild type infection kinetics. by Charles C. Kim (123878)

“…Days depicted in blue and orange represent a 1.5-fold decrease or increase, respectively, in Ly6c^lo monocyte frequencies in blood and spleen of mice infected with <i>P. chabaudi</i>. …”

Over-expression and inhibition of miR-221 and miR-222 result in modulation of p27. by Beatrice Cardinali (120407)

“…<p>Western blot analysis of p27 in myotubes derived from (A) QMb-ts and primary QMb and (B) C2C12, L6C5 and MSC myoblasts transfected with control siGFP (siGFP), miR-221 (221), miR-222 (222) or both (221+222) duplex RNAs and allowed to differentiate for two days. p27 expression in (C) QMb-ts myotubes transfected with antisense inhibitors to GFP (aGFP), used as control, miR-221 (a221), miR-222 (a222) or both (a221+a222) and shifted to 35°C for 24 hours and in (D) C2C12 myoblasts transfected with the same duplexes in GM and analysed 24 hours. …”

CHD8 depletion by RNAi is detrimental to B-ALL cells <i>in vitro</i> and <i>in vivo</i>. by Jennifer R. Shingleton (829013)

“…An increase in the percentage of GFP+ cells indicates positive selection conferred by shRNA expression, while a decrease indicates negative selection. <b>(B)</b> Western blot showing decreased CHD8 expression in B-ALL cells conferred by both shRNAs (4 days following retroviral infection). …”

Primer pairs for RT-qPCR. by Yoichi Kurokawa (22290520)

“…Conversely, exposure to endogenous prooxidants (dopamine and adrenaline), certain food-derived polyphenols (chrysin and 3-<i><i>O</i></i>-methylquercetin), or 1,2-naphthoquinone led to a significant decrease (<0.5-fold) in Rmst expression. …”

RT-qPCR data tables. by Yoichi Kurokawa (22290520)

“…Conversely, exposure to endogenous prooxidants (dopamine and adrenaline), certain food-derived polyphenols (chrysin and 3-<i><i>O</i></i>-methylquercetin), or 1,2-naphthoquinone led to a significant decrease (<0.5-fold) in Rmst expression. …”

2-AA down-regulates the transcription of many genes involved in the translational capacity of the cell. by Yok-Ai Que (70055)

“…Exogenously added 2-AA decreases polysomes levels. Ribosomal extracts from PA14 cells grown in the absence (left panel) or presence (right panel) of exogenously added 2-AA were separated in a 25% to 5% sucrose density gradient. …”

Regulation of spine neck resistance does not generate robust changes in synaptic efficacy. by Allan T. Gulledge (325673)

“…Following a 20-fold decrease in spine neck resistance, the same synaptic conductance generates a 1.14 mV EPSP at the spine head, and a 0.77 mV EPSP in the dendritic shaft: a boost of synaptic efficacy (“LTP") of 7.1%. …”

Assessing mitochondrial function. by Ana Sofia Rodrigues (491559)

“…Cells were incubated in a medium without glucose and ECAR was accessed during consumption of Glucose (added at the third time point at a final concentration of 5mM) and in the presence of oligomycin (1μM added at the sixth point) and 2DG (10mM at the ninth point). …”

Simulated models of motion can be differentiated based on Heteromotility features. by Jacob C. Kimmel (4768185)

“…(D) The Confusion Matrix of a representative Random Forest classifier trained to distinguish four simulated models of motion shown in (A), mean accuracy of 99.8% (5-fold CV). …”

Time course of changes in global background synaptic conductances during perfusion with bicuculline. by Stuart David Greenhill (509476)

“…The time course of changes in I∶E ratio show that this occurred more rapidly in L5 than L3 but reached a similar end-point whereas that in L2 never reached the same level as that in either of the deeper layers.…”

File S1 - <i>Lactobacillus gasseri</i> SF1183 Affects Intestinal Epithelial Cell Survival and Growth by Blanda Di Luccia (407048)

“…Figure S4, enlargment of part of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0069102#pone-0069102-g005" target="_blank">Fig. 5</a> showing the output of the FACS analysis.…”