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70561
Mitochondrial Complex IV Remodeling after miR-181c Treatment.
Published 2014“…(D) Western blot shows the changes of other isoforms of mitochondrial respiratory chain complex IV. We have observed a significant decrease in the protein content of COX VIIa in the miR-181c overexpression groups, but no effect on COX 5A and COX 5B. α-tubulin was used as the loading control. …”
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70562
The effects of different modes of neurogenesis on OB structure and function.
Published 2022“…The guided addition mode (green) had the strongest effect, leading to an average relative reduction of 23.4% (SEM = 0.0078, bottom panel), with 94.9% of all odor pairs having a net decrease in correlation (SEM = 0.0130). Meanwhile, the control mode (gray) produced little change in the relative reduction (mean = 2.5%, SEM = 0.0180), with 45.4% of odor pairs experiencing net decorrelation (SEM = 0.0548), about what one would expect from chance. …”
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70563
Table_1_Prevalence and WGS-based characteristics of MRSA isolates in hospitals in Shanghai, China.XLS
Published 2022“…<p>Methicillin-resistant Staphylococcus aureus (MRSA) isolates remain a serious threat to global health despite a decrease in MRSA infections since 2005. …”
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70564
The influence of health policy on early diagnosis and surgical incidence of developmental dysplasia of the hip
Published 2018“…The results suggest that the health promotion policy is associated with an increase in early diagnosis and subsequently a decrease in surgeries for DDH.</p></div>…”
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70565
Risk factors for mortality of children with zoonotic visceral leishmaniasis in Central Tunisia
Published 2017“…The risk factors for in-hospital death identified by a multivariate analysis were: bleeding at admission (OR = 25.5, 95% CI: 2.26–287.4; p = 0.009), white cell count less than 4000/mm3 (OR = 5.66, 95% CI: 1.16–27.6; p = 0.032), cytolysis (OR = 28.13, 95% CI: 4.55–173.6; p < 0.001), and delay between onset of symptoms and admission ≥ 15 days (OR = 11, 95% CI: 1.68–72; p = 0.012).…”
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70566
ScTx modulates AP frequency, duration, and spike amplitude.
Published 2016“…(C) Mean AP spike amplitude increase from 42.87±5.07 mV to 53.25±3.78 mV (<i>p</i> ≤ 0.05) in D15 tissue (<i>n</i> = 6) and from 45.5±4.96 mV to 56.21±3.37 mV in D18 tissue (<i>n</i> = 6). …”
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70567
DataSheet_1_Clonal evolution in tyrosine kinase inhibitor-resistance: lessons from in vitro-models.pdf
Published 2023“…(Gln61Lys) variant provided a strong benefit for CML cells under TKI exposure visible by increased cell number (6.2-fold, p < 0.001) and decreased apoptosis (-25%, p < 0.001), proving the functionality of our approach. …”
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70568
Table_1_Clonal evolution in tyrosine kinase inhibitor-resistance: lessons from in vitro-models.xlsx
Published 2023“…(Gln61Lys) variant provided a strong benefit for CML cells under TKI exposure visible by increased cell number (6.2-fold, p < 0.001) and decreased apoptosis (-25%, p < 0.001), proving the functionality of our approach. …”
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70569
Roadmap toward energy-positive upfront nitrogen removal process in baseload LNG plant
Published 2022“…The results show that UNrem of 87.5% from the NG feed can reduce the total power requirements by 0.24%, increase the production flow rate by 4.4%, and decrease the exergy losses by 0.23% compared with the base case. …”
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70570
Local Infusion of Insulin Restores AMPH-Evoked DA Release in Striatum of STZ-Treated Rats
Published 2013“…<p>Summary data for HSCA (<i>n</i> = 5–7). When measured in the dorsal striatum and compared to saline-treated control subjects, STZ-induced depletion of insulin (STZ) resulted in a significant reduction in the rate of DA efflux in response to local injection of AMPH (400 μM/125 nl; (A) as well as a decrease in the maximum amount of released DA (B) and the rate of DA clearance (C) with respect to control. …”
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70571
<i>mecR2</i> is essential for the optimal expression of β-lactam resistance in strains with functional <i>mecI-mecR1</i> regulatory locus.
Published 2012“…Note that film was exposed for 4 h whereas in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002816#ppat-1002816-g005" target="_blank">Figure 5A</a> it was exposed for 48 h.…”
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70572
Functional capacity and mental state of patients undergoing cardiac surgery
Published 2017“…Results: This study assessed nine patients (eight males) aged 62.4 ± 6.3 years with a BMI of 29.5 ± 2.3 kg/m2. There was a significant decrease in DASI scores and VO2 from preoperative to postoperative status (p = 0.003 and p = 0.003, respectively). …”
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70573
Changes in Membrane Plasmalogens of <i>Clostridium pasteurianum</i> during Butanol Fermentation as Determined by Lipidomic Analysis
Published 2015“…When butanol is produced by bacterial cells, then the cells are not subjected to severe stress and responded to it by relatively slowly changing the content of fatty acids and plasmalogens, while after a pulse addition of external butanol (to a final non-lethal concentration of 0.5 % v/v) the cells reacted relatively quickly (within a time span of tens of minutes) by increasing the total plasmalogen content.…”
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70574
Association analysis, given linkage, conditional on the top SNP.
Published 2013“…The regression coefficients refer to the estimated change in the phenotype for each dose of the rarer SNP allele.</p>a<p>Since we used a liability threshold model for analysis of the dichotomous trait (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003147#s4" target="_blank">methods</a> section), the direction of effect on EBNA-1 discrete serostatus is opposite of the sign of the regression coefficient, but is in the same direction as the regression coefficient for the quantitative trait (e.g. for SNP rs204999, the minor allele is associated with a decrease in EBNA-1 antibody level and seronegativity).…”
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70575
The SMART Randomised Controlled Trial
Published 2023“…A small change approach may therefore be an appropriate strategy to reduce the 0.5 to 1 kg of average adult weight gain seen each year and may lead to decreased prevalence of overweight and obesity over time. …”
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70576
Hierarchical transformation between consecutive network layers enhances word recognition performance and robustness of the optimal HSNN.
Published 2020“…<p>(<b>a</b>) The average word accuracy at 5 dB SNR systematically increases across network layers for the optimal HSNN (<b>a</b>, blue) whereas the high-resolution HSNN exhibits a systematic reduction in word recognition accuracy (<b>a</b>, red). …”
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70577
Data from: Habitat loss predicts the functional extinction of fish from Amazonian streams during the Anthropocene
Published 2021“…The simulated extinction of vulnerable species led to a decrease in both the mean body size of the community and functional rarity, and culminated in abrupt losses of ecosystem function after 5% and 10% of extinction at local and regional scales. …”
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70578
Length and GC Content Variability of Introns among Teleostean Genomes in the Light of the Metabolic Rate Hypothesis
Published 2014“…<div><p>A comparative analysis of five teleostean genomes, namely zebrafish, medaka, three-spine stickleback, fugu and pufferfish was performed with the aim to highlight the nature of the forces driving both length and base composition of introns (i.e., bpi and GCi). …”
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70579
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70580
Effect of Intramuscular Injection of pH, lactate, ATP, and α,β–meATP on Muscle Withdrawal Threshold.
Published 2015“…<p>Muscle withdrawal threshold was measured before and 30 minutes after injection of physiologic and supraphysiologic concentrations of pH, lactate, ATP, and α,β–meATP. (A) pH dose response curve. Rats were injected with normal saline adjusted to neutral pH (n = 6), pH 4.0 (n = 12), pH 4.5 (n = 6), pH 5.0 (n = 6), and pH 6.0 (n = 6). …”