Edge time series, computed as the element-wise product of two z-scored calcium time series, measures instantaneous co-fluctuation between pairs of nodes pre- (left) and post- (righ... by Douglas Blackiston (234987)

“…In pre- puncture networks there is no clear pattern in co-fluctuations across the organoids, though in post- puncture networks there is a general decrease from strong co-fluctuations and amplitudes to some baseline levels.…”

Time-course of mRNA expression of IGF-system genes and the activation levels of signalling mediators in the E18.8 cochlea. by Hortensia Sanchez-Calderon (186893)

“…<p>(<b>A–D</b>) mRNA expression levels of <i>Igf1</i>, <i>Igf1r</i>, <i>Igfbp2</i> and <i>Igfbp3</i> were analyzed by qRT-PCR in <i>Igf1^+/+</i> (open circles) and <i>Igf1^−/−</i> (closed circles) mice at E15.5 and E18.5 (n = 8), P5, P15, P30, P60 and P90 (n = 6). …”

Polyglutamine Induced Misfolding of Huntingtin Exon1 is Modulated by the Flanking Sequences by Vinal V. Lakhani (249536)

Guanine metabolism. by Patricia Kuzaj (635687)

“…(d) Metabolic pathway of purine breakdown of guanine, including enzymatic steps of guanine deaminases (GDA) and xanthine oxidoreductases (XOR) with formation of reactive oxygen species (ROS). Arrows point to the comparison of patients and healthy controls: red (significantly increased), green (significantly decreased), light green (decreased, by trend), yellow (unchanged).…”

Growth inhibition of BT474 cells by targeting Y211 phosphorylation of PCNA. by Huajun Zhao (189292)

“…</b> DNA synthesis activity in the treated cells was determined by a colorimetric BrdU-incorporation analysis. For each data point, the amount of incorporated BrdU was normalized to the percentage of viable cells, as determined by a side-by-side MTT assay. …”

Paclitaxel induced polyneuropathy can be detected with the Catwalk method. by Petra Huehnchen (470721)

“…The swing phase (squares, long dashed line) increases, while the stance phase (open triangles, dotted line) and the duty cycle (circles, solid line) decreases. Duty cycle expresses the stance phase as a percentage of the entire step cycle (stand + swing). …”

Fig 2 - by Azam Shahvaroughi-Farahani (10924390)

“…<i>(</i><b><i>b</i></b><i>) Experiment 2 (Arm length estimate−Tactile/proprioceptive approach)</i>: Participants seated with eyes closed while estimating the length of their right/left arm (plus hand) on the table by using a tactile starting point. The participant then was instructed to move the right index finger on the table towards the right to indicate the length of his/her right/left arm (plus hand).…”

GSNO reduces fibrin branchpoint density, but does not alter the fiber density/branchpoint ratio. by Ryon M. Bateman (141170)

“…Panels A,B,C show a multiphoton image with three branch points (B1,B2,B3) and their corresponding contour map and surface plots, respectively. …”

ITDs and azimuthal head-turn angle. by Laura Hausmann (257760)

“…<p>(A) The azimuthal head-turn angles were pooled for stimulation with individualized HRTFs (dotted, owls H and S), responses to owl 39 normal (black, all three owls) and to owl 39 ruffcut (blue, all three owls). …”

Site-specific mutagenesis of MAEL HMG-box domain. by Pavol Genzor (711322)

“…(C-F) Mutation of individual arginines (R) results in the complete loss of binding to DNA 4WJ suggesting that they are essential for complex formation. The R8A mutant fold appears to be affected (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0120268#pone.0120268.s002" target="_blank">S2B Fig.…”

The influence of MTA1 expression on the malignant phenotypes of 1E8 cells. by Hongyan Wang (41596)

“…<p>(A) Treatment with MTA1 siRNA decreased MTA1 expression efficiently and enhanced E-cadherin expression. …”

Cohesin Is Limiting for the Suppression of DNA Damage–Induced Recombination between Homologous Chromosomes by Shay Covo (246428)

“…The decreased survival reflected a reduction in DSB repair. …”

Synthesis and Structure of 3,3-Dimethylindoline Squaraine Rotaxanes by Tia S. Jarvis (4039019)

“…One of the new rotaxanes emits an orange light (560–650 nm), and there is a 10-fold enhancement in the squaraine fluorescence quantum yield upon encapsulation as a rotaxane. …”

BRMS1 suppressed OPN expression in HCC cells. by Yanhua Wu (141984)

“…A positive log₂-transformed fold change value indicates higher expression levels in tumorous specimens compared to the non-tumorous specimens while a negative value indicates decreased relative mRNA levels.…”

Probing musculoskeletal control. by Andrew C. Murphy (4778547)

“…The plot is numbered as follows, corresponding to <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2002811#pbio.2002811.t005" target="_blank">Table 5</a>: thumb (1), index finger (2), middle finger (3), hand (4), all fingers (5), wrist (6), elbow (7). …”

Baroreflex and non-baroreflex function determined by three methods. by Dan Sapoznikov (162802)

“…The modal class (the maximal, most frequent HR-SBP histogram value) was taken as a set point of spontaneous activity. The SBP-HR pair classes in quadrant 1 (low SBP associated with high HR values) and in quadrant 3 (high SBP associated with low HR values) are representative of baroreflex episodes, while quadrants 2 (low SBP with low HR) and 4 (high SBP with high HR) represent non-baroreflex episodes. …”

SNP Detection in mRNA in Living Cells Using Allele Specific FRET Probes by Liya Dahan (456368)

“…As determined by an Acceptor Photobleaching method, FRET levels were higher in cells transfected with perfect match FRET probes whereas a single mismatch showed decreased FRET signal. …”

Fig 2 - by Li-Li Li (1800595)

“…<p><b>Change in competition behaviors over time in the 2-tray Phase I (A) and 1-tray Phase II (B).</b> Each point represents the frequency of a competition behavior in each session. …”

Supplementary Material for: Oral Glucose Loading Modulates Plasma β-Amyloid Level in Alzheimer’s Disease Patients: Potential Diagnostic Method for Alzheimer’s Disease by Takeda S. (4133011)

Halauxifen-Methyl+Diclosulam: New Option to Control Conyza spp. Prior Soybean Sowing by F.H. KRENCHINSKI (5054456)