Silencing of Ribosomal Protein S9 Elicits a Multitude of Cellular Responses Inhibiting the Growth of Cancer Cells Subsequent to p53 Activation by Mikael S. Lindström (110158)

“…<div><h3>Background</h3><p>Disruption of the nucleolus often leads to activation of the p53 tumor suppressor pathway through inhibition of MDM2 that is mediated by a limited set of ribosomal proteins including RPL11 and RPL5. …”

Supplementary Material for: Pre- and post-operative Exercise and Nutrition Therapy in Patients with Esophageal Cancer Undergoing Esophagectomy: A Prospective Interventional Study by figshare admin karger (2628495)

Table 1_Early identification of sarcopenia in patients with diabetes mellitus combined with osteoporosis: development and validation of a gender-specific nomogram.docx by Mingzhong Yu (21215879)

“…In female patients, body mass index and creatine kinase were associated with a decreased risk of sarcopenia, while age, weight-adjusted waist index, and low-density lipoprotein cholesterol were associated with an increased risk. …”

Supplementary Data from HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy by Michael F. Emmons (14935638)

“…S1) HDAC expression levels in melanoma cells S2) Cell lines that are resistant to BRAF inhibitors have upregulated c-Jun protein expression S3) Inhibiting HDAC6 does not resensitize BRAF/MEK resistant cells to BRAF inhibitors S4) BRAF/MEK inhibitor withdrawal decreases HDAC8 expression over time S5) Knocking down or elevating HDAC8 levels does not change cell proliferation S6) Expression of HDAC8 increased ERK activity and resistance upon treatment with BRAF-MEK inhibitors S7) Knocking down HDAC8 in BRAFi naïve cells increased apoptosis and BIM expression while decreasing ERK activity after BRAFi activity. …”

A standardized extract of Centella asiatica (ECa 233) prevents temporomandibular joint osteoarthritis by modulating the expression of local inflammatory mediators in mice by Nattapon ROTPENPIAN (10409963)

“…Methodology A mouse model was induced by analyzing the CFA-injected TMJ on days 7, 14, and 21. …”

Simvastatin treatment reduces the cholesterol content of membrane/lipid rafts, implicating the N -methyl-D-aspartate receptor in anxiety: a literature review by Júlia Niehues da Cruz (12847682)

DataSheet1_Real-World Management and Clinical Outcomes of Stroke Survivors With Atrial Fibrillation: A Population-Based Cohort in Spain.docx by Clara L. Rodríguez-Bernal (11829377)

“…Regarding temporal trends, management with OAC increased by 20%, with a decrease of 50% for APT during the study period. …”

Image 2_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.tif by Chang Liu (35901)

“…Background<p>Sleep deprivation (SD) has been associated with cognitive deficits, mediated by mechanisms such as neuroinflammation and oxidative stress. Acupuncture, a core component of traditional Chinese medicine, has shown promise in mitigating SD-induced cognitive impairment. …”

Table_2_Preoperative Oral Gabapentin in the Management of Postoperative Catheter-Related Bladder Discomfort in Adults: A Systematic Review and Meta-Analysis.docx by Yu-Ting Wang (166811)

“…</p><p>Conclusion: Preoperative oral gabapentin as an adjunct to surgery is effective in decreasing the risk and severity of CRBD over a short time after surgery, and it can decrease postoperative pain without significant side effects. …”

Image 1_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.tif by Chang Liu (35901)

“…Background<p>Sleep deprivation (SD) has been associated with cognitive deficits, mediated by mechanisms such as neuroinflammation and oxidative stress. Acupuncture, a core component of traditional Chinese medicine, has shown promise in mitigating SD-induced cognitive impairment. …”

Table_1_Preoperative Oral Gabapentin in the Management of Postoperative Catheter-Related Bladder Discomfort in Adults: A Systematic Review and Meta-Analysis.docx by Yu-Ting Wang (166811)

“…</p><p>Conclusion: Preoperative oral gabapentin as an adjunct to surgery is effective in decreasing the risk and severity of CRBD over a short time after surgery, and it can decrease postoperative pain without significant side effects. …”

Data_Sheet_1_Provenance Differences in Water-Use Efficiency Among Sessile Oak Populations Grown in a Mesic Common Garden.docx by Arivoara Rabarijaona (12984509)

“…In response to severe drought, populations with a higher increase in WUE_i showed a lower decrease in GI. …”

Identification of <em>Orch3</em>, a Locus Controlling Dominant Resistance to Autoimmune Orchitis, as Kinesin Family Member 1C by Roxana del Rio (108216)

“…These findings may provide mechanistic insight into how polymorphism in other kinesins such as <em>KIF21B</em> and <em>KIF5A</em> influence susceptibility and resistance to human autoimmune diseases.…”

Study on the Multimodal Anticancer Mechanism of Ru(II)/Ir(III) Complexes Bearing a Poly(ADP-ribose) Polymerase 1 Inhibitor by Yuliang Yang (1954498)

“…A series of novel ruthenium­(II) and iridium­(III) complexes (<b>Ru1</b>–<b>Ru3</b> and <b>Ir1</b>–<b>Ir3</b>) with different ancillary ligands and a PARP-1-inhibitory chelating ligand 2-(2,3-dibromo-4,5-dimethoxybenzylidene)­hydrazine-1-carbothioamide (<b>L1</b>) were designed and prepared. …”

Table2_Preclinical Evidence of Paeoniflorin Effectiveness for the Management of Cerebral Ischemia/Reperfusion Injury: A Systematic Review and Meta-Analysis.DOCX by Anzhu Wang (5501090)

“…Paeonia lactiflora Pall. is a commonly used for ischemic stroke management in traditional Chinese medicine; its main active ingredient is paeoniflorin (PF). …”

Study on the Multimodal Anticancer Mechanism of Ru(II)/Ir(III) Complexes Bearing a Poly(ADP-ribose) Polymerase 1 Inhibitor by Yuliang Yang (1954498)

“…A series of novel ruthenium­(II) and iridium­(III) complexes (<b>Ru1</b>–<b>Ru3</b> and <b>Ir1</b>–<b>Ir3</b>) with different ancillary ligands and a PARP-1-inhibitory chelating ligand 2-(2,3-dibromo-4,5-dimethoxybenzylidene)­hydrazine-1-carbothioamide (<b>L1</b>) were designed and prepared. …”

Study on the Multimodal Anticancer Mechanism of Ru(II)/Ir(III) Complexes Bearing a Poly(ADP-ribose) Polymerase 1 Inhibitor by Yuliang Yang (1954498)

“…A series of novel ruthenium­(II) and iridium­(III) complexes (<b>Ru1</b>–<b>Ru3</b> and <b>Ir1</b>–<b>Ir3</b>) with different ancillary ligands and a PARP-1-inhibitory chelating ligand 2-(2,3-dibromo-4,5-dimethoxybenzylidene)­hydrazine-1-carbothioamide (<b>L1</b>) were designed and prepared. …”

Data_Sheet_1_A Novel Promazine Derivative Shows High in vitro and in vivo Antimicrobial Activity Against Staphylococcus aureus.docx by Troels Ronco (414344)

“…Surprisingly, in vitro studies showed that the novel compound, JBC 1847 exhibited highly increased antimicrobial activity against eight Gram-positive pathogens (MIC, 0.5–2 mg/L), whereas a disc diffusion assay indicated that the properties as an adjuvant were lost. …”

Is circumferential urethral mobilization an overdo? A prospective outcome analysis of dorsal onlay and dorso - lateral onlay BMGU for anterior urethral strictures by Gaurav Prakash (5137481)

Study on the Multimodal Anticancer Mechanism of Ru(II)/Ir(III) Complexes Bearing a Poly(ADP-ribose) Polymerase 1 Inhibitor by Yuliang Yang (1954498)

“…A series of novel ruthenium­(II) and iridium­(III) complexes (<b>Ru1</b>–<b>Ru3</b> and <b>Ir1</b>–<b>Ir3</b>) with different ancillary ligands and a PARP-1-inhibitory chelating ligand 2-(2,3-dibromo-4,5-dimethoxybenzylidene)­hydrazine-1-carbothioamide (<b>L1</b>) were designed and prepared. …”