Transducer mechanisms activated by D1-like receptors. by Catalina Valdés-Baizabal (701863)

“…The use of H89 in the intracellular solution decreased the inhibitory effect of A-68930 from 29 ± 4% to 16 ± 5% at −10 mV (<i>P</i> = 0.08). …”

Evolutionary Consequences of Altered Atmospheric Oxygen in <em>Drosophila melanogaster</em> by Marc Charette (198776)

“…<div><p>Twelve replicate populations of <em>Drosophila melanogaster</em>, all derived from a common ancestor, were independently evolved for 34+ generations in one of three treatment environments of varying PO₂: hypoxia (5.0–10.1 kPa), normoxia (21.3 kPa), and hyperoxia (40.5 kPa). …”

Treatment of landfill leachate using Fenton Processes and Photo-Fenton Solar by Fábio Moraes da Costa (5376350)

“…These conditions led to a decrease in the toxicity of leachates' coefficient values to a degree equal to 50 % - for Aliivibrio fischeri greater than 50% - indicating a more suitable leachate for further biological treatment.…”

<i>Def6</i> RNA rescues the <i>def6</i> MO-induced phenotype. by Katerina Goudevenou (199855)

“…ANOVA single factor and two-tailed Student's <i>t</i>-tests showed a significant (p<0.001; three asterisks) increase in the angle after injection of 2.5 ng <i>def6</i> MO and a significant (p<0.001; three asterisks) decrease in the angle after addition of <i>def6</i> RNA. …”

Reconsolidation and extinction after different strengths of training. by Remus Osan (3639754)

“…Bars indicate freezing in vehicle (dark blue) and anisomycin (light blue) groups before (left set) and after (right set) reexposure with <i>t</i> = 4 (mean ± S.E.M. of 100 simulations). As occurs in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0023113#pone-0023113-g003" target="_blank">Figure 3C</a>, freezing is decreased by anisomycin administration, indicating reconsolidation blockade. …”

Activation of the UPR can override the inhibition of NF-κB by IKK inhibitors in cancer cells with elevated IKK activity. by Arvin B. Tam (124164)

“…A reduction in P-IκBα and increase in total IκBα were seen corresponding to a decrease in IKK activity. …”

Apocynin restores vasorelaxation of the diabetic aorta. by Sachin Gupte (363123)

“…</b> Diabetes did not alter the response to SNAP (a nitric oxide donor). Values are mean±SEM of 5 animals. * p<.05 compared to Wistar.…”

Penguin ease of transport for real vs. fully-compensated travel vectors relative to the ground during the return journey with respect to depth use and prey acquisition. by Richard M. Gunner (12652026)

“…<p><b>(a)</b> Mean ease of e of transport (±1 SE, in m/J) is shown across the proportion of the return distance to the colony for the real penguin travel vector in any direction towards the colony (orange), the real penguin travel vector along the line-of-sight to the colony (purple), and the fully-compensated travel vector (cyan). …”

Pre-seeded scaffolds promote more effective tissue regeneration. by Paul P. Bonvallet (708039)

“…*Represents p<0.01 for all treatment groups that are significantly different from each other within the same time point. Also, all treatment groups significantly decreased over time (p<0.001).…”

Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability-0 by Andreas Peth (85734)

“…Whereas the anti-CSN5 antibody revealed a reduction to 23% as compared to the control, there was no decrease of the CSN complex observed with the anti-CSN8 antibody. …”

Supplementary Material for: Lobar Quantification by Ventilation/Perfusion SPECT/CT in Patients with Severe Emphysema Undergoing Lung Volume Reduction with Endobronchial Valves by Kristiansen J.F. (6802865)

“…V/Q SPECT/CT-assessed volume of the targeted lobe decreased by a mean of –395 mL and a relative mean of –26.8%, whilst ventilation and perfusion decreased by a relative mean of –37.1 and –25.7%. …”

The effect of dopamine on Δψ_m and [Ca²⁺]_c in midbrain neurons and astrocytes. by Sonia Gandhi (49260)

“…Figure bi demonstrates the increase in Rh123 fluorescence at 1 minute, 6 minutes and 12 minutes that reflects mitochondrial membrane depolarisation in PINK1 ko cells. c, d: Single cell traces of PINK1 ko neurons demonstrating that dopamine induced decrease in ΔΨ_m occurs independently of any change in [Ca²⁺]_c in some cells (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037564#pone-0037564-g001" target="_blank">Figure 1c</a>), whereas in other cells dopamine induced decrease in ΔΨ_m co-incides with a rise in [Ca²⁺]_c (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037564#pone-0037564-g001" target="_blank">Figure 1d</a>). e: Incubation with D1/D5 receptor antagonist SCH23390 (20 µM) did not alter the dopamine induced calcium signal or mitochondrial depolarisation in PINK1 ko neurons. f: Dopamine induced mitochondrial depolarisation was prevented by application of the PTP inhibitor 1 µM cyclosporine A.…”

Elimination testing with adapted scoring reduces guessing and anxiety in multiple-choice assessments, but does not increase grade average in comparison with negative marking by Jef Vanderoost (5108072)

“…The comparison is structured around seven hypotheses: in comparison with negative marking, elimination testing with adapted scoring leads to (1) a similar average score (no grade inflation); (2) students expressing their partial knowledge; (3) a decrease in the number of blank answers; (4) no gender bias in the number of blank answers; (5) a reduction in guessing; (6) a decrease in self-reported test anxiety; and finally (7) students preferring elimination testing with adapted scoring over negative marking.…”

Inhibition of autophagy potentiates the response to chemotherapy only in the spheroids sensitive to GDC-0980. by Dario Barbone (111176)

“…<p>(A) M28 and REN spheroids were transfected with ATG5 (left panels) and ATG7 siRNA (right panels) and treated with GDC-0980 (1 μM), bortezomib (25 nM), ammonium chloride (NH₄⁺, 10 mM) or the combination for 6 h. …”

Pial arteriolar dilatory responses to ACh and NMDA are significantly impaired during ECM and can be partially restored by BH4 supplementation. by Peng Kai Ong (424201)

“…<p><b>A</b>: Mean arteriolar vessel diameters before compound superfusion in all studies. …”

Ras transformation affects the circadian clock via MAPK signalling. by Angela Relógio (193817)

“…(<b>B</b>) Western Blot analysis of RAS protein expression for the HaCaT cell lines and its derivatives (HaCaTI7, HaCaTII4, A5RT3), shows clear RAS overexpression measured in A5RT3. …”

Behavioral Logic for Operant Training and Discrimination Testing by Samar B Mehta (274037)

“…As this behavior was established, <i>N</i> was increased from 0.063 s to 1.5 s.</p> <p>(C) Stimulus training. All trials in this stage were initiated by a 1.5-s nose poke. …”

Data Sheet 1_Diagnostic utility of hematological and biochemical markers for cystic echinococcosis in Tibetan patients of Sichuan, China.pdf by Meng Ma (2075878)

“…</p>Results<p>(1) Patients with CE displayed significant abnormalities in blood and biochemical indicators compared to healthy subjects, including increased levels of platelet count, eosinophil percentage, basophil percentage, prothrombin time, fibrinogen, activated partial thromboplastin time, total bilirubin, direct bilirubin, γ-glutamyltransferase, aspartate aminotransferase, and alkaline phosphatase. Conversely, there was a decrease in lymphocyte percentage, hemoglobin concentration, mean corpuscular volume, and hematocrit. (2) Prothrombin time levels were markedly elevated beyond normal reference values, with prolonged prothrombin time identified as a significant predictor for CE. (3) The area under the receiver operating characteristic curve (AUC) for predicting CE based on prothrombin time was 0.969, while the AUC for predicting CE using a combination of prothrombin time and eosinophil percentage was 0.982.…”

Video_1_Robustness and Scalability of Regional Climate Projections Over Europe.mp4 by Dominic Matte (6270914)

“…<p>Climate change projections for Europe consistently indicate a future decrease in summer precipitation over southern Europe and an increase over northern Europe. …”

<i>In vitro</i> effect of c-myc overexpression on <i>EBI3</i> expression level. by Julie Gonin (344703)

“…The expression of <i>EBI3</i> in c-myc-ER transfected cells relative to that measured in control tranfected cells is represented. The percentage of decrease is indicated. A higher concentration of 4-OHT (1 µM) did not result in higher repression of <i>EBI3</i> expression (not shown). …”