Randomised, double-blind, parallel group comparison of Ashitaba (<i>Angelica Keiskei</i>) chalcone effects on visceral fat areas and waist circumference of overweight persons by Norikazu Watanabe (18282327)

“…<p>This randomised, placebo-controlled, double-blind, parallel-group study aimed to determine whether encapsulated Ashitaba chalcone (16 mg comprising 10.1 mg 4-hydroxyderricin and 5.9 mg xanthoangelol) could reduce obesity in 17 men and 25 women with a body mass index (BMI) of 25 to < 30. …”

Table1_Remimazolam Protects Against LPS-Induced Endotoxicity Improving Survival of Endotoxemia Mice.pdf by Xiaolei Liu (104141)

“…We further found that remimazolam not only inhibited the activation of MAPK signal pathway at 15 min after LPS treatment but also disturbed Rab5a related TLR4 expression at cell surface in response to LPS at a later time. …”

ROCK regulates spine morphology through RLC-T18, S19 di-phosphorylation. by Jennifer L. Hodges (207936)

“…Neurons were treated with 100 µM Y-27632 for 2 hours or 20nM calyculin A for 20min or left untreated. <b>D</b>) Y-27632 decreases the levels of spine-associated RLC-PP staining; whereas calyculin A increases it. …”

Imino-oxy Acetic Acid Dealkylation as Evidence for an Inner-Sphere Alcohol Intermediate in the Reaction Catalyzed by Peptidylglycine α-Hydroxylating Monooxygenase by Neil R. McIntyre (2249155)

“…Subsequent dealkylation of the α-hydroxyglycine by another enzyme, peptidylamidoglycolate lyase (PAL. EC 4.3.2.5), yields a bioactive amide and glyoxylate. PHM is a noncoupled, type II dicopper monooxygenase which activates O₂ at only a single copper atom, Cu_M. …”

Irisin ameliorates bone loss in ovariectomized mice by Y. Luo (1398985)

“…Consistently, the OVX mice treated with r-irisin showed a significantly increased number of osteoblasts on the trabecular surface and a significantly decreased number of osteoclasts. …”

Impact of modifications to periplasmic volume around optimal solution of ABC cell at nutrient concentration of 1 nM. by Noele Norris (10826554)

“…<p>To understand why the periplasm inflates as the nutrient concentration decreases to 1 nM, we plot the proportion of bound transport units (A) and effective half-saturation constant, K_M, (B) as we modify the periplasmic volume of the optimal solution for a nutrient concentration of 1 nM. …”

Imino-oxy Acetic Acid Dealkylation as Evidence for an Inner-Sphere Alcohol Intermediate in the Reaction Catalyzed by Peptidylglycine α-Hydroxylating Monooxygenase by Neil R. McIntyre (2249155)

“…Subsequent dealkylation of the α-hydroxyglycine by another enzyme, peptidylamidoglycolate lyase (PAL. EC 4.3.2.5), yields a bioactive amide and glyoxylate. PHM is a noncoupled, type II dicopper monooxygenase which activates O₂ at only a single copper atom, Cu_M. …”

Noble metal -doped graphitic carbon nitride photocatalyst for enhancement photocatalytic decomposition of antibiotic pollutant in wastewater under visible light by Viet N.M.

“…The doping of Ag not only decreased the band-gap energy and particle size, but also enhanced the separation of charge carriers and decreased the electron/hole recombination in the g-C3N4 structure. …”
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Effects of Maternal Exposure to Ultrafine Carbon Black on Brain Perivascular Macrophages and Surrounding Astrocytes in Offspring Mice by Atsuto Onoda (550095)

“…PVM granules were found to be enlarged and the number of PAS-positive PVMs was decreased in UfCB-exposed offspring. These results suggested that in offspring, “normal” PVMs decreased in a wide area of the CNS through maternal UfCB exposure. …”

Soil Organic Carbon Project by Minglong Liu (19558708)

“…From 2000 to 2022, POC increases by 21.8% while MAOC decreases by 5.3%, leading to a net gain of 11.0% in SOC storage and a 29.1% increase in the POC/MAOC ratio. …”

Data_Sheet_1_Species, Spatial-Temporal Distribution, and Contamination Assessment of Trace Metals in Typical Mariculture Area of North China.doc by Dawei Pan (1691827)

“…The concentrations of Cu, Pb, Cd, and Zn decreased from nearshore to offshore, showing a distinctly regional variation. …”

Image_1_Migration, invasion, and metastasis are mediated by P-Rex1 in neuroblastoma.tiff by Jillian C. Jacobson (14271370)

“…Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 (P-Rex1) has been found to stimulate migration, invasion, and metastasis in several adult malignancies. …”

Effects of Local Gains on Shape of Dose Response Curves in the Anti-Stress Gene Regulatory Network in Figure 2 by Qiang Zhang (45005)

“…<div><p>(A) Enhancing local gain <i>r</i>₁ through dimerization or trimerization of transcription factor T increases the superlinearity of Y versus S dose response curve, decreases the superlinearity of T versus S and G versus S dose response curves.…”

UNC-73 (Trio) is required in rectal epithelial cells for the Dar response to infection. by Rachel McMullan (183027)

“…Mutations in <i>unc-73(ce362)</i>, and <i>ect-2(ku427)</i>, but not other RhoGEF's, significantly decreased the percentage of Dar animals (A). The UNC-73 gene contains two RhoGEF domains, one specific for Rac (RhoGEF1) and the other specific for Rho (RhoGEF2) (B). …”

Monocyte to M1 Macrophage Polarization is Blunted Following FGF-9 Treatment. by Dinender K. Singla (462521)

“…<b>P</b>: 2 weeks post-MI, M1 macrophage popoluations are significantly decreased in the MI+FGF-9 group. n = 5 animals/group. …”

datasheet1_Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway.zip by Lihua Cui (298054)

“…<p>Pancreatic fibrosis is a pathological characteristic of chronic pancreatitis (CP) and pancreatic cancer. …”

Effects of DNA topoisomerase catalytic inhibitors on the APH-induced common fragile site breakage. by Laura W. Dillon (457426)

“…All data were averaged from 5–7 replicated experiments. All statistical analyses were performed using a two-tailed Student’s T-test. …”

Generation of Atoh1-LKB1^-/- conditional knockout mice. by Yuqin Men (783410)

“…(B) Western blot analysis of Lkb1 in the cochlea of Atoh1-LKB1^-/- and wild-type mice at P14. A 48.6-kD LKB1 protein was decreased obviously in the cochlea of Atoh1-LKB1^-/- mice compared with the controls. …”

Forced Notch signaling does not affect commissural axons to cross the midline. by Ming Shi (78991)

“…<p>Double immunostaining for GFP and TAG1 was performed after electroporation of empty and NICD vectors. (A–C) In the control, GFP⁺ (A) and TAG1⁺ (B) axons cross the ventral midline normally. …”

National Trends in Utilization and In-Hospital Outcomes of Surgical Aortic Valve Replacements in Spain, 2001-2015 by Rodrigo Jiménez-García (320379)

“…IHM decreased over time (from 8.13% in 2001-05 to 5.39% in 2011-15). …”