Exposure to Perfluorooctane Sulfonate In Utero Reduces Testosterone Production in Rat Fetal Leydig Cells by Binghai Zhao (509145)

“…<div><p>Background</p><p>Perfluorooctane sulfonate (PFOS) is a synthetic material that has been widely used in industrial applications for decades. …”

Table 6_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…</p>Conclusion<p>HQH mitigates CYP-induced hippocampal neurotoxicity by decreasing oxidative stress, and inflammation, with HSP90AA1 being a key target, providing a novel therapeutic strategy for chemotherapy-associated cognitive impairment.…”

Presentation_1_Heat Stress Altered the Vaginal Microbiome and Metabolome in Rabbits.pdf by Yu Shi (117923)

“…Among them, the endocrine hormone estradiol (E₂) increased in the Heat group and was positively associated with a number of metabolites such as linolelaidic acid (C18:2N6T), N-acetylsphingosine, N-oleoyl glycine, trans-petroselinic acid, syringic acid, 2-(1-adamantyl)-1-morpholinoethan-1-one, 5-OxoETE, and 16-heptadecyne-1,2,4-triol. …”

Long-Term Trends of Per- and Polyfluoroalkyl Substances (PFAS) in Suspended Particular Matter from German Rivers Using the Direct Total Oxidizable Precursor (dTOP) Assay by Bernd Göckener (7527578)

“…Trends based on target analysis (∑PFCA_target: −10.0%, ∑PFSA_target: −8.2%) were more pronounced than in the dTOP analysis (∑PFCA_dTOP: −4.2%; ∑PFSA_dTOP: −5.3%), suggesting that conventional target analysis overestimated actual decreases as precursors are not considered. …”

Image_1_Heat Stress Altered the Vaginal Microbiome and Metabolome in Rabbits.TIF by Yu Shi (117923)

“…Among them, the endocrine hormone estradiol (E₂) increased in the Heat group and was positively associated with a number of metabolites such as linolelaidic acid (C18:2N6T), N-acetylsphingosine, N-oleoyl glycine, trans-petroselinic acid, syringic acid, 2-(1-adamantyl)-1-morpholinoethan-1-one, 5-OxoETE, and 16-heptadecyne-1,2,4-triol. …”

Table_2_Heat Stress Altered the Vaginal Microbiome and Metabolome in Rabbits.xls by Yu Shi (117923)

“…Among them, the endocrine hormone estradiol (E₂) increased in the Heat group and was positively associated with a number of metabolites such as linolelaidic acid (C18:2N6T), N-acetylsphingosine, N-oleoyl glycine, trans-petroselinic acid, syringic acid, 2-(1-adamantyl)-1-morpholinoethan-1-one, 5-OxoETE, and 16-heptadecyne-1,2,4-triol. …”

Data_Sheet_1_Inhibition of phosphorus removal performance in activated sludge by Fe(III) exposure: transitions in dominant metabolic pathways.docx by Yiyihui Hong (18812251)

“…</p>Results<p>Experimental results revealed that prolonged Fe(III) exposure induced a transition in the dominant phosphorus removal mechanism within activated sludge, resulting in a diminished availability of phosphorus for bio-metabolism. …”

DataSheet1_Glacier Runoff Variation Since 1981 in the Upper Naryn River Catchments, Central Tien Shan.zip by Tomas Saks (10861360)

“…The basins contain more than 1,000 glaciers, which cover a total area of 776 km². We model the mass balance and runoff contribution of all glaciers with a simplified energy balance melt model and distributed accumulation model driven by ERA5 LAND re-analysis data for the time period of 1981–2019. …”

Table 1_Dose-dependent effects of testosterone on proteins related to nitric oxide signaling pathway and trophic factors in the spinal cord of adolescent trained rats.docx by Katarzyna Nierwińska (6321125)

“…</p>Methods<p>Adult male Wistar rats were trained using a motor-driven treadmill for 6 weeks (40–60 min, 5 times per week) and/or were treated for 6 weeks with two doses of testosterone (i.m.; 8 mg/kg or 80 mg/kg body weight). …”

Supplementary Material for: Plasma Xanthine Oxidase Activity Is Predictive of Cardiovascular Disease in Patients with Chronic Kidney Disease, Independently of Uric Acid Levels by Gondouin B. (4157221)

“…Oxidative stress seems to play a pivotal role in this process, and purine metabolism may be involved in CKD-related oxidative stress. …”

DataSheet1_Glacier Runoff Variation Since 1981 in the Upper Naryn River Catchments, Central Tien Shan.zip by Tomas Saks (10861360)

“…The basins contain more than 1,000 glaciers, which cover a total area of 776 km². We model the mass balance and runoff contribution of all glaciers with a simplified energy balance melt model and distributed accumulation model driven by ERA5 LAND re-analysis data for the time period of 1981–2019. …”

Data Sheet 1_Shengxian decoction alleviates cyclophosphamide-induced immunosuppression via improving B cell-mediated immune responses.docx by Chengyu Yang (10223976)

“…Background<p>Chemotherapy is a prevalent and extensively utilized cancer treatment modality. …”

Supplementary Material for: Resveratrol Inhibits Proliferation and Induces Apoptosis through the Hedgehog Signaling Pathway in Pancreatic Cancer Cell by Mo W. (4478518)

“…The expression of downstream target genes of the Hedgehog pathway such as Gli1, Ptc1, CCND1 and BCL-2 were significantly decreased after 12.5 µ<i>M</i> resveratrol treatment, which demonstrated a similar change of gene expression when Gli1 was knocked down by the RNAi technique in PANC-1 cells. …”

Table 3_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…</p>Conclusion<p>HQH mitigates CYP-induced hippocampal neurotoxicity by decreasing oxidative stress, and inflammation, with HSP90AA1 being a key target, providing a novel therapeutic strategy for chemotherapy-associated cognitive impairment.…”

Table_1_Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1.DOCX by Shuai Mao (1627021)

“…<p>Left ventricular (LV) adverse remodeling and the concomitant functional deterioration contributes to the poor prognosis of patients with myocardial infarction (MI). Thus, a more effective treatment strategy is needed. …”

Table 1_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…</p>Conclusion<p>HQH mitigates CYP-induced hippocampal neurotoxicity by decreasing oxidative stress, and inflammation, with HSP90AA1 being a key target, providing a novel therapeutic strategy for chemotherapy-associated cognitive impairment.…”

Percentages of dividing lymphocytes 72 hours after mitogenic stimulation. by Fanny Gaignier (541785)

“…(<b>B</b>) Percentages of dividing CD3⁺ T cells, CD3⁺CD8⁺ Tc cells and CD3⁺CD4⁺ Th cells in response to ConA. No significant difference was obtained for dividing T cells despite the decreases observed for the HU group compared to C mice.…”

Whole-Body Counter(WBC) and food radiocesium contamination surveys in Namie, Fukushima Prefecture by Yoichiro Hosokawa (339409)

“…Moreover, the radioactivity of seven items in these 10 items decreased from fiscal 2012 to fiscal 2015. Mushrooms had high radioactivity and were produced over a wide area.…”

Dendritic Cells Regulate Treg-Th17 Axis in Obstructive Phase of Bile Duct Injury in Murine Biliary Atresia by Yong-jun Liu (5660170)

“…The proportion of Th17 cells at 7 days post-infection was decreased if Treg cells isolated from normal adult mice, but not Treg cells from the livers of mice with BA, were intraperitoneally transferred on day 5 of life. …”

Data_Sheet_1_Acupuncture With deqi Modulates the Hemodynamic Response and Functional Connectivity of the Prefrontal-Motor Cortical Network.pdf by Xiaopeng Si (11276703)

“…Results showed that: (1) acupuncture manipulation caused significantly increased acupuncture behavioral deqi performance compared with tactile controls. (2) The bilateral prefrontal cortex (PFC) and motor cortex were significantly inhibited during acupuncture manipulation than controls, which was evidenced by the decreased power of oxygenated hemoglobin (HbO) concentration. (3) The bilateral PFC’s hemodynamic responses showed a positive correlation trend with acupuncture behavioral performance. (4) The network connections with bilateral PFC as nodes showed significantly increased functional connectivity during acupuncture manipulation compared with controls. (5) Meanwhile, the network’s efficiency was improved by acupuncture manipulation, evidenced by the increased global efficiency and decreased shortest path length. …”