NOTCH1 Gain of Function in Germ Cells Causes Failure of Spermatogenesis in Male Mice by Zaohua Huang (439674)

“…Spermatogenesis in these mutants was progressively affected with age, resulting in decreased testis weight and sperm count. Analysis of downstream target genes of NOTCH1 signaling showed an increased expression of <i>Hes5</i>, with a reduction of the spermatogonial differentiation marker, <i>Neurog3</i> expression in the mutant testis. …”

Summary of different review. by Biniam Alemayehu (22530422)

“…Results show that the proposed method reduces active power losses by 72.064%, decreases voltage deviation from 24.63% to 4.5% and improves the minimum bus voltage from 0.7537 pu to 0.9550 pu. …”

Phytochemical analysis and fungicide potential of Pouteria ramiflora against Lasiodiplodia theobromae by Ademir Kleber M Oliveira (4771896)

“…The experimental design was completely randomized with five replications, and the treatments were constituted of a factorial of seven extracts/fractions and six concentrations. …”

Table_3_The Effects of Temperature Acclimation on Swimming Performance in the Pelagic Mahi-Mahi (Coryphaena hippurus).docx by Rachael M. Heuer (4623886)

“…Aerobic scope and U_crit were highest in 28°C-acclimated fish. 20°C-acclimated mahi experienced significantly decreased aerobic scope and U_crit relative to 28°C-acclimated fish (57 and 28% declines, respectively). 32°C-acclimated mahi experienced increased mortality and a significant 23% decline in U_crit, and a trend for a 26% decline in factorial aerobic scope relative to 28°C-acclimated fish. …”

Depletion of the Chromatin Looping Proteins CTCF and Cohesin Causes Chromatin Compaction: Insight into Chromatin Folding by Polymer Modelling by Mariliis Tark-Dame (641719)

“…PLoS ONE 5: e12218.). We show that compaction can be explained by selectively decreasing the number of short-range loops, leaving long-range looping unchanged. …”

Data Sheet 1_Role of RGS17 in cisplatin-induced cochlear inflammation and ototoxicity via caspase-3 activation.zip by Raheem F. H. Al Aameri (14951800)

“…C57BL/6J mice treated with two cycles of cisplatin (3.5 mg/kg) showed a significant elevation in ABR thresholds, along with loss of outer hair cells and inner hair cells synapse. …”

Dataset: Global oyster reef restoration and recovery by Deevesh Ashley Hemraj (9058922)

“…We found that whilst restoration initiates a rapid increase in biodiversity and abundance of 2- to 5-fold relative to unrestored habitat, recovery rate decreases substantially within a few years post-restoration and accumulated global recovery debt persists at >35% per annum. …”

Data_Sheet_1_Rufomycin Exhibits Dual Effects Against Mycobacterium abscessus Infection by Inducing Host Defense and Antimicrobial Activities.doc by Cho Rong Park (11253450)

“…This study shows that the rufomycins 4/5/6/7 (Rufomycin 4–7), which targets ClpC1 as a subunit of caseinolytic protein complex ClpC1/ClpP1/ClpP2 of mycobacteria, exhibits a dual effect in host innate defense and in vivo antimicrobial activities against a rough morphotype of Mycobacterium abscessus (Mabs-R), a clinically severe morphotype that causes hyperinflammation. …”

Table_1_The Effects of Temperature Acclimation on Swimming Performance in the Pelagic Mahi-Mahi (Coryphaena hippurus).docx by Rachael M. Heuer (4623886)

“…Aerobic scope and U_crit were highest in 28°C-acclimated fish. 20°C-acclimated mahi experienced significantly decreased aerobic scope and U_crit relative to 28°C-acclimated fish (57 and 28% declines, respectively). 32°C-acclimated mahi experienced increased mortality and a significant 23% decline in U_crit, and a trend for a 26% decline in factorial aerobic scope relative to 28°C-acclimated fish. …”

Size and temporal dynamics of EPS digestion. by Sammy Pontrelli (10744534)

“…<p><b>A)</b> Number of ions in each enzyme digest falling in the decreased, bell-shaped, or increased categories. …”

Image_6_The Effects of Temperature Acclimation on Swimming Performance in the Pelagic Mahi-Mahi (Coryphaena hippurus).pdf by Rachael M. Heuer (4623886)

“…Aerobic scope and U_crit were highest in 28°C-acclimated fish. 20°C-acclimated mahi experienced significantly decreased aerobic scope and U_crit relative to 28°C-acclimated fish (57 and 28% declines, respectively). 32°C-acclimated mahi experienced increased mortality and a significant 23% decline in U_crit, and a trend for a 26% decline in factorial aerobic scope relative to 28°C-acclimated fish. …”

Data_Sheet_1_PhageWeb – Web Interface for Rapid Identification and Characterization of Prophages in Bacterial Genomes.PDF by Ailton Lopes de Sousa (4045322)

“…In the PhageWeb analysis, the Sn index was 86.1% and the PPV was approximately 87%, while the second best tool presented Sn and PPV values of 83.3 and 86.5%, respectively. These numbers allowed us to observe a greater precision in the regions identified by PhageWeb while compared to other prediction tools submitted to the same tests. …”

New Coating TENG with Antiwear and Healing Functions for Energy Harvesting by Xiang Kong (707688)

“…The result shows that when the mesoporous silica is used as a carrier and perfluorooctylethanol is loaded, the short-circuit current (<i>I</i>_sc) and output voltage (<i>V</i>_o) of the coating TENG reach as high as 10 μA and 220 V, respectively, which are 4–5 times higher than those of pure acrylate. …”

Resveratrol Directly Binds to Mitochondrial Complex I and Increases Oxidative Stress in Brain Mitochondria of Aged Mice by Naïg Gueguen (93376)

“…<i>In vitro</i>, using solubilized complex I, we demonstrated a competition between NAD+ and resveratrol. At low doses (<5μM), resveratrol stimulated complex I activity, whereas at high dose (50 μM) it rather decreased it. …”

Convergence property of PSO. by Biniam Alemayehu (22530422)

“…Results show that the proposed method reduces active power losses by 72.064%, decreases voltage deviation from 24.63% to 4.5% and improves the minimum bus voltage from 0.7537 pu to 0.9550 pu. …”

Overall Comparison of all cases. by Biniam Alemayehu (22530422)

“…Results show that the proposed method reduces active power losses by 72.064%, decreases voltage deviation from 24.63% to 4.5% and improves the minimum bus voltage from 0.7537 pu to 0.9550 pu. …”

<i>CABLES1</i> expression is reduced in human subcutaneous adipose tissue in obesity and type 2 diabetes but may not directly impact adipocyte glucose and lipid metabolism by Susanne Hetty (7587506)

“…<p>Cdk5 and Abl enzyme substrate 1 (CABLES1) is a cell cycle regulator that has previously been identified as a candidate gene for obesity-related phenotypes, but little is known about its role in adipose tissue metabolism. …”

Charge Profile Analysis Reveals That Activation of Pro-apoptotic Regulators Bax and Bak Relies on Charge Transfer Mediated Allosteric Regulation by Crina-Maria Ionescu (158447)

“…The network was mediated by a hub of three residues on helix 5 of the hydrophobic core of Bax. …”

Preference-based measure of health-related quality of life and its determinants in sickle cell disease in Nigeria by Adedokun Oluwafemi Ojelabi (7879526)

“…Women had lower utility scores with a small effect size (d = 0.17). Utility score increased with level of education but decreased with age, anxiety, frequency of pain episodes and number of co-morbidities.…”

SGLT2 Inhibition Increases Fasting Glucagon but Does Not Restore the Counterregulatory Hormone Response to Hypoglycemia in Participants with Type 1 Diabetes by Schafer C. Boeder (11741399)

“…Adults with type 1 diabetes (<i>n</i> = 22) were treated with the SGLT2 inhibitor dapagliflozin (5 mg daily) or placebo for 4 weeks in a randomized, double-blind, crossover study. …”