Discovery of Triazolyl Derivatives of Cucurbitacin B Targeting IGF2BP1 against Non-Small Cell Lung Cancer by Fan-Fan Shang (16953264)

Subjects:

Data Sheet 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf by Wei Gong (112494)

“…This study investigates the role of the long non-coding RNA GPRC5D-AS1 in the development and progression of sarcopenia through its regulation of SLC7A11. …”

Supplementary file 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf by Wei Gong (112494)

“…This study investigates the role of the long non-coding RNA GPRC5D-AS1 in the development and progression of sarcopenia through its regulation of SLC7A11. …”

Predicted metabolite levels for each reaction intermediate shown in Figure 7 under conditions in which the NAD+:NADH ratio is 31 (Bennett et al. [26]), or decreased by either 0.1-f... by William R. Cannon (608586)

Influence of Acidic pH on Hydrogen and Acetate Production by an Electrosynthetic Microbiome by Edward V. LaBelle (608387)

“…Cyclic voltammetry revealed a 250 mV decrease in hydrogen overpotential and a maximum current density of 12.2 mA/cm² at −765 mV (0.065 mA/cm² sterile control at −800 mV) by the <i>Acetobacterium</i>-dominated community. …”

Freezing test of acclimated and non-acclimated Col-0, <i>gun5</i> and <i>cch</i> plants. by Peter Kindgren (795049)

Effect of anthocyanin extract administration on colon myeloperoxidase activity and expression as compared with 5-ASA, in TNBS-induced colitis. by Sónia R. Pereira (3854467)

Table_5_Sub-Inhibitory Concentrations of Chlorhexidine Induce Resistance to Chlorhexidine and Decrease Antibiotic Susceptibility in Neisseria gonorrhoeae.DOCX by Jolein G. E. Laumen (11754755)

ND-75^KD flies have reduced mobility, seizures and decreased lifespan. by Lucy Granat (5570813)

Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors by Maris A. Cinelli (1309419)

“…We previously developed a class of membrane-permeable 2-aminoquinoline inhibitors and later rearranged the scaffold to decrease off-target binding. …”

HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching. by Michael Anthony Ruiz (726055)

“…However, transfection of SUZ12 siRNA significantly reduced endothelial branching compared to HG+control siRNA. [NG+control siRNA = 5mM D-glucose + 100nM control siRNA, HG+control siRNA = 25mM D-glucose + 100nM control siRNA, HG+EZH2 siRNA = 25mM D-glucose + 100nM EZH2 siRNA, HG+SUZ12 siRNA = 25mM + 100nM SUZ12 siRNA; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to U6 or β-actin and expressed as a fold change of NG+control siRNA].…”

Antibody response elicited by SARS-CoV-2 vaccines. by Chris Davis (647632)

MBOAT7 rs641738 (C>T) is associated with NAFLD progression and decreased ASCVD risk in elder Chinese population by Zhang jing (14062485)

Relative expression (fold-change) of immune genes in mitogen-stimulated splenic lymphocytes. by Chaiwat Monmai (6377270)

Gene silencing of <i>nectin-2</i> decreases GIC susceptibility to NKL cell-mediated cell death. by Fabian Wolpert (803768)

Heparin (GAG-hed) inhibits LCR activity of Human Papillomavirus type 18 by decreasing AP1 binding-5 by Rita Villanueva (65963)

“…Nuclear extracts obtained from HeLa cells were exposed to GAG-hed at indicated concentrations for 10 min before labelled probe addition (Panels B and D). On panel A and C, complex specificity is denoted by competition assays with a 100 fold excess of indicated oligonucleotide competitor. …”

A summary of the included study characteristics. by Zahra Tajik (20752452)

“…The results show that one month after the NSPT, there was no significant difference in the mean visfatin level of GCF (SMD: -3.91, 95%CI: -9.83, 2.01, p = 0.195, I-square, 96.6%, random effect model, n = 2) and serum (SMD: -0.33, 95%CI: -0.98, 0.33, p = 0.332, fixed effect model, n = 1), but 2, 3 and 6 months after NSPT, the mean visfatin level of GCF and serum decreased significantly. There is no significant difference one month after NSPT in diabetic patients (SMD: -5.83, 95%CI: -15.5, 3.83, p = 0.237, I-square, 97.4%, random effects model, n = 2), but three (SMD: -2.44, 95%CI: -3.37, -1.15, p = 0.001, I-square, 75.9%, random effects model, n = 3) and six months (SMD: -2.41, 95%CI: -3.81, -1.01, p = 0.001, I-square, 78.7%, random effects model, n = 2) after the treatment, a significant decrease is observed in the mean GCF visfatin level. …”

Met decreases MYH1/2 and p21 expression and increases Myf5 and MyoD levels in myotubes. by Eleonora Maniscalco (14599854)

Decreasing HIV viral loads across subdistricts in KwaZulu-Natal province, South Africa, between 2018 and 2022. by Lilishia Gounder (15240167)

LOH unlinks 189R/R from a stop codon with masking effects on phenotype. by Pétra Vande Zande (17628246)