R848 mediated RANTES, but not TNF-α production, is significantly decreased in TRAM^−/− iBMDMs. by Enda Shevlin (628477)

Binding affinity determination of ACE2 variants with SARS-CoV-2 Spike. by Stuart A. MacGowan (11326845)

PNNs decrease after EE. (A–D₁) PNNs, stained by WFA (red), enwrap DCN projection neurons, labeled by SMI32 antibodies (blue). by Simona Foscarin (231429)

Genomic inactivation of the <i>PIWI</i> gene in <i>L. infantum</i> and <i>L. major</i> strains leads to a decrease in amastigote growth and disease pathology. by Prasad K. Padmanabhan (85254)

The 10 most highly regulated genes in sputum and blood from microarray analysis; a positive fold change  =  increase in frequent exacerbators compared to zero exacerbators, a negative fold change  =  decrease in frequent exacerbators compared to zero exacerbators. by Dave Singh (114223)

“…</p><p>The 10 most highly regulated genes in sputum and blood from microarray analysis; a positive fold change  =  increase in frequent exacerbators compared to zero exacerbators, a negative fold change  =  decrease in frequent exacerbators compared to zero exacerbators.…”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC₅₀ value of 61 nM compared to that of Tamoxifen (IC₅₀ value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. Interestingly, <b>4f</b> showed remarkable PI3K/AKT/mTOR inhibitory activity with 0.18-, 0.27-, and 0.39-fold decrease in their concentration (reduction in controls from 6.64, 45.39, and 86.39 ng/mL to 1.24, 12.35, and 34.36 ng/mL, respectively). …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC₅₀ value of 61 nM compared to that of Tamoxifen (IC₅₀ value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. Interestingly, <b>4f</b> showed remarkable PI3K/AKT/mTOR inhibitory activity with 0.18-, 0.27-, and 0.39-fold decrease in their concentration (reduction in controls from 6.64, 45.39, and 86.39 ng/mL to 1.24, 12.35, and 34.36 ng/mL, respectively). …”

DnaK inhibits protein synthesis in vivo and in vitro. by Carissa Chan (18310140)

S5 Fig - by Cynthia Alsayyah (18452506)

“…This indicates that inhibiting the entry of citrate into mitochondria induces the same effects as inhibiting the synthesis of peroxisomal citrate (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002602#pbio.3002602.g005" target="_blank">Fig 5E</a>). …”

DnaK’s ATPase activity is stimulated by ribosomes and required to reduce protein synthesis. by Carissa Chan (18310140)

Intravital 2-photon microscopy imaging of acute <i>C</i>. <i>albicans</i> infections of the kidney in real time in a living host. by Fitz Gerald S. Silao (9384713)

DnaK associates with intact ribosomes and not with dismantled ribosomes. by Carissa Chan (18310140)

Trigger factor hinders DnaK-mediated reduction of protein synthesis. by Carissa Chan (18310140)

Preparations of DnaK protein are pure. by Carissa Chan (18310140)

Viral loads in serum at day 3 post-EBOV infection. by Olivier Reynard (354756)

DnaK does not refold heat-denatured luciferase when incubated in the presence of ribosomes. by Carissa Chan (18310140)

Comparative analysis of the antimicrobial activity of hGRNL, bNK2A, and pNKL against O157 strain EDL933 in Müeller-Hinton broth (MHB) or sodium phosphate buffer (NaPB). by Erika N. Biernbaum (12647386)

HPV16 PsV infection decreases following SLPI treatment or anti-annexin A2 antibody inhibition of A2t. by Andrew W. Woodham (140650)

Table_1_Staple line lockstitch reinforcement decreases clinically relevant pancreatic fistula following distal pancreatectomy: Results of a propensity score matched retrospective a... by Feng Tian (121350)

“…</p>Methods<p>This retrospective study enrolled consecutive patients scheduled to undergo distal pancreatectomy at a large tertiary hospital. A comparison was conducted between lockstitch reinforcement and non-reinforcement for remnant closure during distal pancreatectomies from August 2016 to February 2021. …”

Monitoring of the weight of guinea pigs treated with anti-EBOV IgGs. by Olivier Reynard (354756)