IRE1 depletion decreases heterochromatin, DNA and H3K9me3 methylation, and UHRF1. by Iratxe Zuazo-Gaztelu (21071939)

Statins Decrease Neuroinflammation and Prevent Cognitive Impairment after Cerebral Malaria by Patricia A. Reis (109310)

“…<div><p>Cerebral malaria (CM) is the most severe manifestation of <em>Plasmodium falciparum</em> infection in children and non-immune adults. Previous work has documented a persistent cognitive impairment in children who survive an episode of CM that is mimicked in animal models of the disease. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Ariadne is a non-hallucinogenic analog in the phenylalkylamine chemical class of psychedelics that is closely related to an established synthetic hallucinogen, 2,5-dimethoxy-4-methyl-amphetamine (DOM), differing only by one methylene group in the α-position to the amine. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Ariadne is a non-hallucinogenic analog in the phenylalkylamine chemical class of psychedelics that is closely related to an established synthetic hallucinogen, 2,5-dimethoxy-4-methyl-amphetamine (DOM), differing only by one methylene group in the α-position to the amine. …”

Resveratrol decreased tumor latency in <i>Sirt1^Y/+</i> mice. by Katherine V. Clark-Knowles (368164)

Glu58 and Arg87 minimal distance decreases upon activation. by Maxime Louet (150102)

The functional half-life of WNV decreases in the presence of virus-specific antibody. by Kimberly A. Dowd (129927)

Eltrombopag markedly decreases levels of ROS in MOLM14 cells. by Anna Kalota (7415)

“…B) Graphic presentation of ROS levels measured by flow cytometry in cells treated with E (5 μM) or DPI (25 μM), an inhibitor of NADPH oxidase known to decrease an intracellular level of ROS, or untreated (CTR) cells. …”

A R13A point mutation in C4 attenuates CLCuMuV infection. by Asigul Ismayil (5698946)

“…<b>(C)</b> The mutant CLCuMuV carrying C4^R13A (CLCuMuV-C4^R13A), which contains a R13A mutation in <i>C4</i>, showed the decreased viral symptom compared to wild type CLCuMuV. …”

Time course of best-corrected visual acuity (BCVA) in recurrence and non-recurrence groups. by Yasuyuki Sotani (20114144)

“…In the non-recurrence group, CRT improved from 482.5 ± 112.8 to 294.7 ± 65.3, 302.0 ± 68.0, 284.7 ± 55.4, 285.3 ± 70.2, 265.2 ± 65.0, and 266.1 ± 78.2 μm at 1, 3, 6, 12, 24, and 36 months, respectively (Kruskal-Wallis test, p < 0.001; <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0332941#pone.0332941.g006" target="_blank">Fig 6</a>).…”

Additional behavioral patterns in the 5€, 100€, and 1000€ treatments. by Pablo Brañas-Garza (336425)

Examples of Significant Increase (A), Significant Decrease (B), Non-Significant Change (C) and Unknown (D) population abundance trends. by Anna M. Magera (478098)

Autophagy inhibition decrease LAMP2 levels and survival of neuroendocrine differentiated LNCaP cells. by Cecilia Morell (729630)

Inhibition of SKI-1/S1P enzymatic activity using PF-429242 impairs activation of the SREBP pathway and correlates with a dramatic decrease in lipid droplet number and area. by Anastasia Hyrina (3860455)

Image_5_v1_Systemic Immune Modulation Alters Local Bone Regeneration in a Delayed Treatment Composite Model of Non-Union Extremity Trauma.jpeg by Casey E. Vantucci (10528263)

“…This overall increase correlated with a decrease in bone volume (P = 0.057) at 6 weeks post-treatment and a significant decrease in mechanical strength at 12 weeks post-treatment compared to untreated rats. …”

TRIM5 restriction of HIV-1 has decreased during evolution leading to humans. by Michael Emerman (12304)

“…Original data is found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000301#pbio.1000301-Goldschmidt1" target="_blank">[30]</a> and shows that the antiviral gene TRIM5 restricted HIV-1 better at points in evolution earlier than the chimp–human common ancestor than it does after that. …”

Decreased 5-hmC expression was associated with <i>TET2</i> downregulation. by Xuejiao Shi (1684186)

Growth, ammonium metabolism, and photosynthetic properties of <i>Ulva australis</i> (Chlorophyta) under decreasing pH and ammonium enrichment - Fig 5 by Leah B. Reidenbach (4620856)

“…<p><b>(A) Light saturation point (E</b>_<b>k</b><b>), (B) initial slope of the curve (</b>α<b>), and (C) slope of photoinhibition at high photon flux densities (</b>β<b>) from rapid light curves for <i>Ulva australis</i> grown under ambient and enriched NH</b>_<b>4</b>^<b>+</b> <b>treatments across a range of pH</b>_<b>T</b>. …”

nanoDSF apparent melting points. by Aleksi Sutinen (10039145)

Subjects:

Video_5_Why Does Child Mortality Decrease With Age? Modeling the Age-Associated Decrease in Mortality Rate Using WHO Metadata From 25 Countries.MP4 by Josef Dolejs (5534258)

“…<p>Background: Our previous study analyzed the age trajectory of mortality (ATM) in 14 European countries, while this study aimed at investigating ATM in other continents and in countries with a higher level of mortality. Data from 11 Non-European countries were used.…”