Ethanol exposure significantly reduced the number of proliferating cells compared to untreated controls in O2 neuromasts of Brn3c GFP-larvae. by Phillip M. Uribe (285454)

“…<p>(A) Under untreated control conditions, proliferating cell nuclear antigen (PCNA)-labeled cells (arrowhead) are primarily non-sensory supporting cells and mantle cells in the neuromast (area demarked by white dotted line). …”

Compared to C57BL/6 mice, chronically CCl₄ injured <i>Pdgfrα^WT/nGFP</i> mice have reduced transcription of fibrotic genes. by Brian J. Hayes (542810)

“…<p>Livers from <i>Pdgfrα^WT/nGFP</i> and C57BL/6 mice that were either uninjured (controls) or treated for 4 weeks with CCl₄ were used to prepare total liver RNA. A) Compared to C57BL/6 mice, expression of <i>Pdgfrα</i> is decreased in <i>Pdgfrα^WT/nGFP</i> mice in uninjured mice and after chronic CCl₄. …”

Fig 1 - by M. Latorre (8840546)

“…<p>Fully developed, mechanobiologically equilibrated, axisymmetric dilatations of an initially cylindrical aortic segment caused by a mild (first column) or severe (second column) localized (via the respective parameter <i>ϑ</i>_{<i>central</i>} in Eq (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008273#pcbi.1008273.e024" target="_blank">9</a>)) loss of elastic fiber integrity (first row, parameter <i>c</i>^<i>e</i>, mild 32% and severe 62% reduction), decrease in collagen cross-linking (second row, parameter , mild 9%, severe 23% reduction), loss of smooth muscle contractility (third row, parameter <i>T</i>_<i>max</i>, mild 60%, severe 100% reduction), compromised mechanosensing (fourth row, parameter <i>δ</i>, mild 7.5%, severe 18.5%, absolute), or compromised mechanoregulation (fifth row, parameter <i>G</i>^<i>c</i>, mild 0.4%, severe 1.2%, relative change), with the risk factors of hypertension (third column, 50% increase in blood pressure) and aortic aging (fourth column, uniform 30% loss of elastic fiber integrity) superimposed on the mild insults. …”

Image_2_Pharmacological Preconditioning Using Diazoxide Regulates Store-Operated Ca2 + Channels in Adult Rat Cardiomyocytes.JPEG by Raúl Sampieri (8297634)

“…Previously, we reported that pharmacological preconditioning (PPC) leads to a decrease in the amplitude of L-type calcium channel current in the heart. …”

Image_1_Liver-Specific Knockdown of Class IIa HDACs Has Limited Efficacy on Glucose Metabolism but Entails Severe Organ Side Effects in Mice.TIF by Nicole Ziegler (6893297)

“…For that, siRNAs selectively targeting HDAC4, 5 and 7 were selected and used to achieve a combinatorial knockdown of these three class IIa HDAC isoforms. …”

Macro-regions of Brazil. by Arnauld Kaufman (12731976)

“…Our results demonstrated a significant increase in the AAPC in Brazil’s less than 1-year-old age group and a decrease in children from 5 to 19 years old. …”

Data Sheet 1_Large scale atmospheric conditions favoring storm surges in the North and Baltic Seas and possible future changes.docx by Nils H. Schade (21676022)

“…Towards the end of the 21st century, the CMIP6 ensemble projects a significant increase in the frequency of westerly effective winds for Cuxhaven under the scenarios SSP3-7.0 and SSP5-8.5. …”

Table_1_Skin-to-blood pH shift triggers metabolome and proteome global remodelling in Staphylococcus epidermidis.XLSX by Luis Gafeira Gonçalves (13873508)

“…Here we studied the impact of pH conditions, mimicking the skin pH (5.5) and blood pH (7.4), in a S. epidermidis commensal strain by means of next-generation proteomics and ¹H NMR-based metabolomics. …”

Table_1_Liver-Specific Knockdown of Class IIa HDACs Has Limited Efficacy on Glucose Metabolism but Entails Severe Organ Side Effects in Mice.docx by Nicole Ziegler (6893297)

“…For that, siRNAs selectively targeting HDAC4, 5 and 7 were selected and used to achieve a combinatorial knockdown of these three class IIa HDAC isoforms. …”

Dissecting the Epstein–Barr virus entry pathway into astrocytes: unfolding the involvement of endosomal trafficking by Annu Rani (11223925)

“…</p> <p>EBV internalization decreased upon depletion of the lipid rafts.</p> <p>The dynamin protein plays a crucial role in EBV entry into astrocytes, and its depletion indicates a decrease in EBV entry.…”

Image_2_Liver-Specific Knockdown of Class IIa HDACs Has Limited Efficacy on Glucose Metabolism but Entails Severe Organ Side Effects in Mice.TIF by Nicole Ziegler (6893297)

“…For that, siRNAs selectively targeting HDAC4, 5 and 7 were selected and used to achieve a combinatorial knockdown of these three class IIa HDAC isoforms. …”

ICD-10 version 2015. by Arnauld Kaufman (12731976)

“…Our results demonstrated a significant increase in the AAPC in Brazil’s less than 1-year-old age group and a decrease in children from 5 to 19 years old. …”

CKDMR in Brazil. by Arnauld Kaufman (12731976)

“…Our results demonstrated a significant increase in the AAPC in Brazil’s less than 1-year-old age group and a decrease in children from 5 to 19 years old. …”

Image_1_Pharmacological Preconditioning Using Diazoxide Regulates Store-Operated Ca2 + Channels in Adult Rat Cardiomyocytes.JPEG by Raúl Sampieri (8297634)

“…Previously, we reported that pharmacological preconditioning (PPC) leads to a decrease in the amplitude of L-type calcium channel current in the heart. …”

Image_1_Skin-to-blood pH shift triggers metabolome and proteome global remodelling in Staphylococcus epidermidis.pdf by Luis Gafeira Gonçalves (13873508)

“…Here we studied the impact of pH conditions, mimicking the skin pH (5.5) and blood pH (7.4), in a S. epidermidis commensal strain by means of next-generation proteomics and ¹H NMR-based metabolomics. …”

Real-Time Cytotoxicity Assay for Rapid and Sensitive Detection of Ricin from Complex Matrices by Diana Pauly (170378)

“…Upon incubation with toxin the cell status and the cytotoxic effect were visualized using a characteristic cell index–time profile. For ricin, tested in concentrations of 0.06 ng/mL or above, a concentration-dependent decrease of cell index correlating with cytotoxicity was recorded between 3.5 h and 60 h. …”

DataSheet1_Real-time simulation of the transplanted tooth using model order reduction.DOCX by Pierre Lahoud (13931149)

“…The use of MOR reduced the time for delivering the root stresses by a mean 5.9 h. The biomechanical behavior of a transplanted tooth simulated by FE models was accurately captured with a significant decrease of computing time. …”

Data_Sheet_1_Impact of Alcohol Outlet Density on Reported Cases of Child Maltreatment in Japan: Fixed Effects Analysis.docx by Yuna Koyama (7462883)

“…Also, a negative association was observed between a change in the incidence of total child maltreatment by father and a change in alcohol outlet density (coefficient = −3.03, 95% confidence interval: −5.78, −0.28).…”

() Equilibria for the M1 RNA-catalyzed processing reaction in the presence of constant Zn as the catalytic cofactor and varying concentrations of Sr that activate the reaction at l... by Simona Cuzic (8015)

“…I(a) = Sr ion that activates processing by decreasing to α; I = inhibitory Sr ion that inhibits cleavage chemistry but also decreases to β. () Dixon plot of the M1 RNA-catalyzed ptRNA cleavage rate at 37°C as a function of [Sr] in the presence of four different fixed Zn concentrations and 5 μM M1 RNA,…”

Table_1_“I Want to Create So Much Stimulus That Adaptation Goes Through the Roof”: High-Performance Strength Coaches' Perceptions of Planned Overreaching.pdf by Lee Bell (12486250)

“…Short-term decreased performance capacity, both during and in the days to weeks following training, was an anticipated by-product of POR, and at times used as a benchmark to confirm that training demand was sufficiently challenging. …”