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point decrease » point increase (Expand Search)
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24401
Junctional Adhesion Molecules (JAMs) - New Players in Breast Cancer?
Published 2022“…</p> <p> </p><p> </p><p>Many factors are thought to be responsible for the development of breast cancer. Genetic factors play a vital role in the predisposition to breast cancer, with mutations of <em><em>BRCA1 </em></em>and <em><em>BRCA2 </em></em>genes accounting for 5–10% of breast cancer cases and being responsible for 80% of inherited breast cancers (Nathanson <em><em>et al</em></em>., 2001). …”
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24402
Supplementary Material for: Osteoporosis-Pseudoglioma Syndrome: Three Novel Mutations in the <i>LRP5 </i>Gene and Response to Bisphosphonate Treatment
Published 2012“…Mutation screening for <i>LRP5</i> revealed homozygous nonsense R1002X mutation in the first patient and homozygous missense mutations V336M and G507S in the second and third patient, respectively. …”
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24403
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24404
Data_Sheet_1_Dynamic Modulation of Mouse Locus Coeruleus Neurons by Vasopressin 1a and 1b Receptors.PDF
Published 2018“…Finally, exposing animals to acute stress increased V1b, but not V1a receptor expression, whilst decreasing AVP immunoreactivity. …”
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24405
5-FU induces major changes in cell morphology in smooth muscle cell cultures.
Published 2013“…<p>Phase contrast microscopy shows that cells treated with 1 or 10 mM of 5-FU (C-H) display a spindle-shaped morphology as compared to untreated cells (A and B). …”
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24406
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24407
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24408
Restoring CDK4 rescues RelA induced proliferation arrest.
Published 2015“…The MTS values were normalized to the Dox- samples for each cell line. Standard error of a triplicate experiment is shown. Dox dependent decrease in proliferation of Hkd-CDK4 was statistically significant compared to Hkd-C cells (p-value: 0.001). …”
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24409
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24410
Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
Published 2013“…Using this approach, a total of 47 proteins showed at least 1.5 fold change between lean and obese subjects. …”
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24411
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24412
Evaluation of various enzymatic assays for glucose dehydrogenase activity of GDH1E5.
Published 2014“…</p><p>All enzyme assays were carried out using purified GDH1E5 over 5 min at 35°C and 75 mM glucose as a substrate. …”
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24413
Intraplantar injection of 0.01% capsaicin or 5 µg CGRP induced heat hyperalgesia.
Published 2014“…(C, D) Paw withdrawal latency was decreased within 5 min of injection (arrow) of CGRP, but not PBS in females and males of both genotypes. …”
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24414
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24415
WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism
Published 2021“…</p> <p><b>Abbreviations</b>: ATF6: activating transcription factor 6; ATG5: autophagy related 5; ATG12: autophagy related 12; ATG16L1: autophagy related 16 like 1; ATP2A1/SERCA1: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1; BALF: bronchoalveolar lavage fluid; BFA: brefeldin A; BMDC: bone marrow-derived dendritic cell; CALR: calreticulin; CANX: calnexin; CCL2/MCP-1: C-C motif chemokine ligand 2; CNS: central nervous system; CT: C-terminal domain; DTT: dithiothreitol; DNAJB9/ERDJ4: DnaJ heat shock protein family (Hsp40) member B9; EAE: experimental autoimmune encephalomyelitis; EIF2A/eIF2α: eukaryotic translation initiation factor 2A; EIF2AK3/PERK: eukaryotic translation initiation factor 2 alpha kinase 3; ERN1/IRE1: endoplasmic reticulum (ER) to nucleus signaling 1; GFP: green fluorescent protein; HSPA5/GRP78/BiP: heat shock protein A5; IFNA: interferon alpha; IFNAR1: interferon alpha and beta receptor subunit 1; IFNB: interferon beta; IFNG/INFγ: interferon gamma; IFNGR2: interferon gamma receptor 2; IL6: interleukin 6; IL10: interleukin 10; IL12A: interleukin 12A; IL23A: interleukin 23 subunit alpha; ITGAX/CD11c: integrin subunit alpha X; ITPR1/InsP3R1: inositol 1,4,5-trisphosphate receptor type 1; MAP1LC3B/LC3B: microtubule associated protein 1 light chain 3 beta; OVA: ovalbumin; PIK3C3/VPS34: phosphatidylinositol 3-kinase catalytic subunit type 3; PLF: predicted lipocalin fold; PPP1R15A/GADD34: protein phosphatase 1 regulatory subunit 15A; RYR1/RyanR1: ryanodine receptor 1, skeletal muscle; SD: signal domain; TGFB/TGF-β: transforming growth factor beta family; Th1: T helper cell type 1; Th17: T helper cell type 17; TM: tunicamycin; TNF/TNF-α: tumor necrosis factor; UPR: unfolded protein response; WLS/wntless: WNT ligand secretion mediator.…”
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24416
Multifunctional Resistive-Heating and Color-Changing Monofilaments Produced by a Single-Step Coaxial Melt-Spinning Process
Published 2012“…Exceptional thermal output levels were reached, with a temperature rising up to over 100 °C at voltages above 110 V. …”
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24417
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24418
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24419
Jacobian determinant maps quantitatively illustrate mutant mouse differences.
Published 2015“…For <i>Dll4</i> mice, statistically significant differences are visible at all time points, including the 17–20 somite stage (A-C). Two different sagittal sections (A, B) and a coronal section (C) through the autoflurorescence image reveal that <i>Dll4</i> mutants have generalized, whole-heart volume increases (red shading). …”
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24420
CNNM4 but not SLC41A1 stimulates TRPM7-mediated divalent cation entry.
Published 2021“…Shown are images taken at a time point between 5 and 10 minutes after application of 30 μM ZnCl<sub>2</sub>. …”