Stably Integrating an Inducible CRISPR-Cas9 to Aug- ment the Mammalian Immune System to Protect Against Viral Infections by Indeever Madireddy (12513346)

Supplementary Material for: Topo-Proteomic in situ Analysis of Psoriatic Plaque under Efalizumab Treatment by Bonnekoh B. (4106116)

“…The treatment was well tolerated. Five of these patients proved to be responders with an average decrease in psoriasis area and severity index (PASI) from 21.3 ± 5.4 (day 0) to 3.9 ± 0.6 (week 12). …”

Altered A-to-I RNA Editing in Human Embryogenesis by Ronit Shtrichman (145914)

“…Overall, our data suggest that A-to-I RNA editing plays a critical role during early human development.…”

Mean and SD of zinc in tissues from control and inoculated gerbils with two isolates of <i>Giardia intestinalis</i>: WB and HGINV. by Angélica González Maciel (18946369)

Egg-laying pattern in relation to provisioning order of prey observed in <i>Isodontia harmandi</i> nests. by Yui Imasaki (12562704)

Percentage of adverse drug reactions (ADRs) for pharmacogene-associated medications. by Emma F. Magavern (20947928)

Inhibition of proliferation and cell-cycle progression of keratinocytes by DCE and CS. by Claudia Scarponi (205759)

Analgesic prescriptions received by patients before commencing the BOA model of care for osteoarthritis: a Swedish national registry study with matched reference and clinical guide... by Allan Abbott (6032138)

“…Since guideline publication, the proportion of the OA cohort having no dispensed prescription analgesics prior to non-pharmacological primary care intervention concordantly increased by 5.0% (95% CI 4.2–5.9). Furthermore, dispensed prescriptions concordantly decreased for non-selective NSAIDs –8.6% (CI –9.6 to –7.6), weak opioids –6.8% (CI –7.7 to –5.9), glucosamine –9.5% (CI –9.8 to –8.8). and hyaluronic acid –1.6% (CI –1.8 to –1.5) but discordantly increased for strong opioids 2.8% (CI 2.1–3.4) and glucocorticoid intra-articular injection for hip OA 2.1% (CI 1.0–3.1).…”

Impact of Gemin5 in protein synthesis: phosphoresidues of the dimerization domain regulate ribosome binding by Salvador Abellan (19499424)

“…In addition, ribosome binding decreased when Ser/Thr 847 and 852–854 are substituted by a non-phosphorylatable residue, consistent with decreased protein stability, and reduced number of associated factors. …”

Curcumin affects the brain amyloid deposition histology patterns as a function of <i>Drosophila</i> genotype. by Ina Caesar (185701)

“…DAPI staining from regions with widespread p-FTAA-positive aggregates were decreased. (K–O) Aβ_{1–42 E22G} expressing flies at day 0, day 5, and day 10, showed a spot-like staining from both p-FTAA and the Aβ specific antibody, but a weaker p-FTAA staining was apparent (c.f. …”

Effect of Suramin, STI571 and mPPIg5 treatment on FL PrP^Sc levels by James M. McCarthy (277504)

“…The % difference in PrP^Sc content between therapeutically treated and mock treated cells at each time point was calculated for each drug (STI571, Suramin and mPPIg5) and the decrease in FL PrP^Sc over time plotted. …”

Fiber cell ultrastructure near the bow region up to a depth of 300 μm. by M. Joseph Costello (3043893)

Dose-response relationships of rhubarb extract to both normal and model rats, as represented by a factor plot. by Jia-bo Wang (124500)

“…By contrast, the alteration pattern in the model rat groups assumed a parabolic shape with increasing dosages. The factor 1 values decreased in the MD₁ and MD₂ groups but decreased to a small degree when the dosage was further increased. …”

Supplementary Material for: The Clinical Characteristics and Risk Factors of Severe COVID-19 by Hu J. (3808027)

“…In addition, abnormal laboratory findings revealing organ dysfunctions were frequently observed in the severe cases, including decrease in albumin (43%, 95% CI = 24–63%) and increase in aspartate aminotransferase (47%, 95% CI = 38–56%), alanine aminotransferase (28%, 95% CI = 16–39%), troponin I/troponin T (TnI/TnT; 29%, 95% CI = 13–45%), and serum Cr (SCr; 10%, 95% CI = 5–15%). …”

Data_Sheet_2_A Multitubular Kidney-on-Chip to Decipher Pathophysiological Mechanisms in Renal Cystic Diseases.PDF by Sarah Myram (10877844)

“…While no significant tube dilation over time was observed with Madin-Darby Canine Kidney (MDCK) cells, wild-type mouse proximal tubule (PCT) cells, or with PCT Pkd1^+/- cells (with only one functional Pkd1 allele), we observed a typical 1.5-fold increase in tube diameter with isogenic PCT Pkd1^-/- cells, an ADPKD cellular model. …”

Data_Sheet_1_A Multitubular Kidney-on-Chip to Decipher Pathophysiological Mechanisms in Renal Cystic Diseases.DOCX by Sarah Myram (10877844)

“…While no significant tube dilation over time was observed with Madin-Darby Canine Kidney (MDCK) cells, wild-type mouse proximal tubule (PCT) cells, or with PCT Pkd1^+/- cells (with only one functional Pkd1 allele), we observed a typical 1.5-fold increase in tube diameter with isogenic PCT Pkd1^-/- cells, an ADPKD cellular model. …”

HP1a protein levels are reduced and its localization pattern is altered by over-expression of CHD1. by Lakshmi Bugga (393594)

“…(D) Western blot analysis reveals that over-expression of CHD1 results in a 5-fold decrease in chromatin-bound HP1a (as measured as a ratio of HP1a to H3 to account for changes in endoreplication or salivary gland size).…”

Incident infection following acute kidney injury with recovery to baseline creatinine: A propensity score matched analysis by Benjamin R. Griffin (5798075)

“…</p><p>Results</p><p>AKI followed by return to baseline creatinine was associated with a 4.5-fold increased odds ratio for infection (odds ratio 4.53 [95% CI, 2.43–8.45]; p<0.0001) within 30 days following discharge. …”

PERK and GCN2 co-operatively regulate spontaneous differentiation in NOKs. by Deo R. Singh (4784112)

Table 1_Zinc transporter ZIP10 supports zinc homeostasis and myoglobin biosynthesis in differentiating C2C12 myoblasts.docx by Geonu Shim (22644404)

“…Among the 14 Zip and 10 ZnT genes profiled, Zip10 showed the largest fold increase in response to zinc depletion. Zip10 knockdown had minimal effects under zinc-sufficient conditions but further decreased Mb expression in zinc-deficient myoblasts without altering viability or major myogenic transcription factors. …”