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point decrease » point increase (Expand Search)
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44141
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44142
The association between previous and future severe exacerbations of chronic obstructive pulmonary disease: Updating the literature using robust statistical methodology
Published 2018“…<div><p>Background</p><p>There is minimal evidence on the extent to which the occurrence of a severe acute exacerbation of COPD that results in hospitalization affects the subsequent disease course. …”
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44143
Core–Shell {Mn<sub>7</sub>⊂(Mn,Cd)<sub>12</sub>} Assembled from Core {Mn<sub>7</sub>} Disc
Published 2017“…HR-ESI-MS was even more precise by revealing three prominent molecular species, Mn<sub>13</sub>Cd<sub>6</sub>, Mn<sub>14</sub>Cd<sub>5</sub> and Mn<sub>15</sub>Cd<sub>4</sub>, having a distribution of metals. …”
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44144
Genetic Polymorphisms in XRCC1, CD3EAP, PPP1R13L, XPB, XPC, and XPF and the Risk of Chronic Benzene Poisoning in a Chinese Occupational Population
Published 2015“…However, the T allele in PPP1R13L rs1005165 (P<0.05) and the GA allele in CD3EAP rs967591 (OR = 0.162; 95% CI: 0039~0.666; <i>P</i> = 0.037) decreased the risk of CBP in men. The haplotype analysis of XRCC1 indicated that XRCC1 rs25487<sup>A</sup>, rs25489<sup>G</sup> and rs1799782<sup>T</sup> (OR = 15.469; 95% CI: 5.536–43.225; <i>P</i><0.001) were associated with a high risk of CBP.…”
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44145
Efficacy and safety of saxagliptin in combination with insulin in Japanese patients with type 2 diabetes mellitus: a 16-week double-blind randomized controlled trial with a 36-week...
Published 2017“…</p> <p><b>Research design and methods</b>: We randomized 240 patients with type 2 diabetes mellitus on insulin monotherapy to 5-mg saxagliptin or placebo as add-on therapy for a 16-week, double-blind period. …”
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44146
Aqueous humor VEGF-A concentration in the pre-IVR and post-IVR NVG eyes.
Published 2016“…Each point represents a measurement from a single patient.…”
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44147
Growth and B12 uptake of <i>C. reinhardtii</i> metE7 in axenic cultures containing <i>7.5×10<sup>−14</sup> mol</i>/<i>mL</i> B12 (i.e. <i>100 ng</i>/<i>L</i>).
Published 2021“…<p>(A) Growth of <i>C</i>. <i>reinhardtii</i> metE7 in Tris minimal medium + 7.5×10<sup>−14</sup> <i>mol</i>/<i>mL</i> B<sub>12</sub> measured by counting cell density using a Z2 particle count analyser (Beckman Coulter Ltd). …”
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44148
An idealized view of the opportunity provided by a comparative and integrated oncology drug development path.
Published 2013“…Factoring in additional costs for comparative studies with this approach of US$150,000 for studies conducted in the preclinical setting, US$250,000 for studies conducted before or during Phases I–II human trials and US$1 million for studies conducted before Phases II–III studies, the total cost of development is estimated at US$2.07 billion. The result may be a decrease in average clinical trial costs per approved drug from US$290 million to US$173 million <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000161#pmed.1000161-Adams1" target="_blank">[5]</a>.…”
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44149
Several VPS-II genes are upregulated in a Δ<i>zur</i> mutant.
Published 2021“…Black circles represent putative Zur binding sites and lines correspond to likely operons. (<b>E</b>) Log 2-fold expression changes for all VSP-II genes (<i>vc0490-vc0516</i>) are shown alongside a schematic of VSP-II open reading frames. …”
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44150
Vision x diagnosis interactions for COP (Panel A) and DFA-ML (Panel B).
Published 2013“…<p>Each participant's data is represented by a single data point in the eyes-open and eyes-closed condition in each panel. …”
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44151
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44152
Diabetes, Drug Treatment and Mortality in COVID-19: A Multinational Retrospective Cohort Study
Published 2021“…Use of DPP-4 inhibitors was associated with a reduction in respiratory complications (24.0% vs 29.2%; RR, 0.82 [95% CI, 0.74-0.90]; <i>P</i> <.001), and continued use of DPP-4 inhibitors after hospitalization was associated with a decrease in mortality compared with those who discontinued use (9% vs 19%; RR, 0.45 [95% CI, 0.28-0.72]; <i>P</i> <.001). …”
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44153
Data_Sheet_1_Expression of vitamin D receptor, CYP24A1, and CYP27B1 in normal and inflamed canine pancreases.DOCX
Published 2023“…This study showed that VDR expression decreased in inflamed pancreases and demonstrated CYP24A1 and CYP27B1 expression in the canine pancreas for the first time. …”
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44154
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44155
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44156
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44157
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44158
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44159
Classical Galactosemia: Insight into Molecular Pathomechanisms by Differential Membrane Proteomics of Fibroblasts under Galactose Stress
Published 2017“…A series of proteins showed opposite fold-changes in the two cell models, whereas others fluctuated in only one of the two models.…”
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44160